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Posterior Cortical Atrophy

Benson, D. F., Davis, R. J., Snyder, B. D.·1988·Archives of Neurology

Abstract

Five patients had progressive dementia heralded by disorders of higher visual function. All eventually developed alexia, agraphia, visual agnosia, and components of Balint's, Gerstmann's, and transcortical sensory aphasia syndromes. Memory, insight, and judgment were relatively preserved until late in the course. Predominant parieto-occipital atrophy was demonstrated on both computed tomography and magnetic resonance imaging in two of the patients; posterior circulation was normal by angiography in the three studied. To date, no pathologic specimen is available for study; speculations on the underlying pathologic condition include an atypical clinical variant of Alzheimer's disease, a lobar atrophy analogous to Pick's disease, or some previously unrecognized entity.

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Metadata

Authors
Benson, D. F., Davis, R. J., & Snyder, B. D.
Venue
Archives of Neurology
Published
1988-07-01
Volume
45
Issue
7
Pages
789-793
ISSN
0003-9942 (ISSN-L)
OpenAlex
W1994514180
Cited by
748
References
0
FWCI
6.17
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Posterior Cortical Atrophy. https://app.cochat.ai/papers/10.1001/archneur.1988.00520310107024
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Benson, D. F., Davis, R. J., & Snyder, B. D. (1988). Posterior Cortical Atrophy. Archives of Neurology. https://doi.org/10.1001/archneur.1988.00520310107024

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