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Cited by 190

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Therapy for Neurocysticercosis: Comparison Between Albendazole and Praziquantel

Takayanagui, Osvaldo Massaiti·1992·Archives of Neurology

Abstract

Praziquantel and albendazole have been recently described as effective drugs for treatment of intraparenchymal brain cysticercosis. We performed a prospective study comparing the efficacy of these drugs. Twenty-two patients were treated with praziquantel and 21 with albendazole. In addition, 16 patients were treated with symptomatic drugs only and used as controls. Treatment was discontinued in two patients receiving praziquantel and one patient receiving albendazole owing to acute decompensation of the increased intracranial pressure, and one of them died. Albendazole and praziquantel were effective when compared with the control group. However, albendazole was significantly more effective than praziquantel in reducing the total number of cysts in the computed tomographic scans (88% vs 50%). Despite these results, however, analysis of clinical course showed a high frequency of neurologic sequelae. Considering the risks and fallibility of anticysticercal therapy, the real solution for this serious disease continues to be prophylaxis of infestation.

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Metadata

Authors
Takayanagui, O. M.
Venue
Archives of Neurology
Published
1992-03-01
Volume
49
Issue
3
Pages
290
ISSN
0003-9942 (ISSN-L)
OpenAlex
W2015302256
Cited by
190
References
1
FWCI
8.54
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Therapy for Neurocysticercosis: Comparison Between Albendazole and Praziquantel. https://app.cochat.ai/papers/10.1001/archneur.1992.00530270106026
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Takayanagui, O. M. (1992). Therapy for Neurocysticercosis: Comparison Between Albendazole and Praziquantel. Archives of Neurology. https://doi.org/10.1001/archneur.1992.00530270106026

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