The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Replication of CLU, CR1, and PICALM Associations With Alzheimer Disease
Open accessAbstract
OBJECTIVE: To test for replication of the association between variants in the CLU, CR1, and PICALM genes with Alzheimer disease. DESIGN: Follow-up case-control association study. SETTING: The Mayo Clinics at Jacksonville, Florida, and Rochester, Minnesota. PARTICIPANTS: Community-based patients of European descent with late-onset Alzheimer disease (LOAD) and controls without dementia who were seen at the Mayo clinics, and autopsy-confirmed cases and controls whose pathology was evaluated at the Mayo Clinic in Jacksonville. Additional samples were obtained from the National Cell Repository for Alzheimer Disease (NCRAD). A total of 1829 LOAD cases and 2576 controls were analyzed. INTERVENTIONS: The most significant single-nucleotide polymorphisms in CLU (rs11136000), CR1 (rs3818361), and PICALM (rs3851179) were tested for allelic association with LOAD. Main Outcome Measure Clinical or pathology-confirmed diagnosis of LOAD. RESULTS: Odds ratios for CLU, CR1, and PICALM were 0.82, 1.15, and 0.80, respectively, comparable in direction and magnitude with those originally reported. P values were 8.6 x 10(-5), .014, and 1.3 x 10(-5), respectively; they remain significant even after Bonferroni correction for the 3 single-nucleotide polymorphisms tested. CONCLUSION: These results show near-perfect replication and provide the first additional evidence that CLU, CR1, and PICALM are associated with the risk of LOAD.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The association of PICALM polymorphisms with late-onset AD has been reported by the majority of GWAS studies (94, 119, 236, 265, 298, 344, 528).”
From Blood-Brain Barrier: From Physiology to Disease and Back (2019) · cites this paper as [94]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Some additional highly replicated risk genes include CR1 , BIN1 , and TREM2 (94, 119, 219, 300, 344, 543).”
From Blood-Brain Barrier: From Physiology to Disease and Back (2019) · cites this paper as [94]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Several GWAS studies have identified CLU as a significant genetic risk factor for sporadic AD (94, 119, 236, 343).”
From Blood-Brain Barrier: From Physiology to Disease and Back (2019) · cites this paper as [94]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. L., & Stadlan, E. (2011) · Neurology · doi:10.1212/01.wnl.0000400650.92875.cf · Cited by 9,882
Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., & Pericak-Vance, M. A. (1993) · Science · doi:10.1126/science.8346443 · Cited by 9,429
Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease
Saunders, A. M., Strittmatter, W. J., Schmechel, D., St. George-Hyslop, P. H., Pericak-Vance, M. A., Joo, S. H., Rosi, B. L., Gusella, J. F., Crapper-MacLachlan, D. R., Alberts, M. J., et al. (1993) · Neurology · doi:10.1212/wnl.43.8.1467 · Cited by 3,786
Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins
Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6448 · Cited by 3,506
Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.440 · Cited by 3,326
Self-citationGenome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
the European Alzheimer's Disease Initiative Investigators, Lambert, J.-C., Heath, S., Even, G., Campion, D., Sleegers, K., Hiltunen, M., Combarros, O., Zelenika, D., Bullido, M. J., et al. (2009) · Nature Genetics · doi:10.1038/ng.439 · Cited by 2,234
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database
Bertram, L., McQueen, M. B., Mullin, K., Blacker, D., & Tanzi, R. E. (2007) · Nature Genetics · doi:10.1038/ng1934 · Cited by 1,857
Role of Genes and Environments for Explaining Alzheimer Disease
Gatz, M., Reynolds, C. A., Fratiglioni, L., Johansson, B., Mortimer, J. A., Berg, S., Fiske, A., & Pedersen, N. L. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.2.168 · Cited by 1,798
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
Rogaeva, E., Meng, Y., Lee, J. H., Gu, Y., Kawarai, T., Zou, F., Katayama, T., Baldwin, C. T., Cheng, R., Hasegawa, H., et al. (2007) · Nature Genetics · doi:10.1038/ng1943 · Cited by 1,167
Self-citation
Cited by
Sorted by citations
Items 101–200 of 208
Genetic variation in Clusterin gene and Alzheimer's disease risk in Han Chinese
Yu, J., Ma, X., Wang, Y., Sun, L., Tan, L., Hu, N., & Tan, L. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.01.010 · Cited by 34
Albani, D., Marizzoni, M., Ferrari, C., Fusco, F., Boeri, L., Raimondi, I., Jovicich, J., Babiloni, C., Soricelli, A., Lizio, R., et al. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180321 · Cited by 31
Ohara, T., Ninomiya, T., Hirakawa, Y., Ashikawa, K., Monji, A., Kiyohara, Y., Kanba, S., & Kubo, M. (2012) · Psychiatric Genetics · doi:10.1097/ypg.0b013e3283586215 · Cited by 32
Gatta, V., Drago, D., Fincati, K., Valenti, M. T., Carbonare, L. D., Sensi, S. L., & Zatta, P. F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0015965 · Cited by 31
Green, A. E., Gray, J. R., DeYoung, C. G., Mhyre, T. R., Padilla, R. M., DiBattista, A. M., & Rebeck, G. W. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2013.12.020 · Cited by 32
CR1, ABCA7, and APOE genes affect the features of cognitive impairment in Alzheimer's disease
Chung, S. J., Kim, M., Kim, Y. J., Kim, J., You, S., Jang, E. H., Kim, S. Y., & Lee, J. (2014) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2014.01.029 · Cited by 32
Hamilton, G., Harris, S. E., Davies, G., Liewald, D. C. M., Tenesa, A., Starr, J. M., Porteous, D. J., & Deary, I. J. (2011) · International Journal of Alzheimer s Disease · doi:10.4061/2011/505984 · Cited by 29
Kisler, K., Sagare, A. P., Lazić, D., Bazzi, S. A., Lawson, E. J., Hsu, C.-J., Wang, Y., Ramanathan, A., Nelson, A. R., Zhao, Z., et al. (2023) · Molecular Neurodegeneration · doi:10.1186/s13024-023-00597-5 · Cited by 29
Gao, Y., Tan, M., Wang, H.-F., Zhang, W., Wang, Z., Jiang, T., Yu, J., & Tan, L. (2016) · Oncotarget · doi:10.18632/oncotarget.7945 · Cited by 30
Sun, D.-M., Chen, H., Zuo, Q.-L., Su, F., Bai, F., & Liu, C. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.05.043 · Cited by 27
Using CSF biomarkers to replicate genetic associations in Alzheimer's disease
Schott, J. M. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.02.008 · Cited by 27
Defects of Nutrient Signaling and Autophagy in Neurodegeneration
Ondaro, J., Hernández-Eguiazu, H., Garciandia-Arcelus, M., Loera‐Valencia, R., Rodríguez-Gómez, L., Jiménez-Zúñiga, A., Goikolea, J., Rodriguez‐Rodriguez, P., Ruiz‐Martínez, J., Moreno, F., et al. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.836196 · Cited by 28
Initiative, A. D. N., Zhu, X., Wang, H.-F., Jiang, T., Lu, H., Tan, M., Tan, C., Tan, L., Tan, L., & Yu, J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-015-9638-8 · Cited by 26
Complement receptor 1 coding variant p.Ser1610Thr in Alzheimer's disease and related endophenotypes
Cauwenberghe, C. V., Bettens, K., Engelborghs, S., Vandenbulcke, M., Dongen, J. V., Vermeulen, S., Vandenberghe, R. R., Deyn, P. P. D., Broeckhoven, C. V., & Sleegers, K. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.03.008 · Cited by 26
Alaylıoğlu, M., Gezen‐Ak, D., Dursun, E., Bılgıç, B., Hanagasi, H. A., Ertan, T., Gurvit, H. I., Emre, M., Eker, E., Uysal, Ö., et al. (2016) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988716640373 · Cited by 25
Martínez, M. F., Martín, X. E., Martín, E. B., Alcelay, L. G., Serrano, I. U., Busto, F. G., Álvarez-Álvarez, M., Salazar, A. M., Gandarias, R. B., Borda, S. I., et al. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-003200 · Cited by 25
Clathrin, adaptors and disease: Insights from the yeast Saccharomyces cerevisiae
Payne, G. S. (2013) · Frontiers in bioscience · doi:10.2741/4149 · Cited by 26
Zhu, R., Liu, X., & He, Z. (2018) · Neurological Sciences · doi:10.1007/s10072-018-3259-8 · Cited by 24
Petrisko, T. J., Gómez-Arboledas, Á., & Tenner, A. J. (2021) · Advances in immunology · doi:10.1016/bs.ai.2021.09.003 · Cited by 23
Multilocus genetic profiling to empower drug trials and predict brain atrophy
Omid Kohannim, A., Hua, X., Rajagopalan, P., Hibar, D. P., Jahanshad, N., Grill, J. D., Apostolova, L. G., Toga, A. W., Jack, C. R., Weiner, M. W., et al. (2013) · NeuroImage Clinical · doi:10.1016/j.nicl.2013.05.007 · Cited by 24
Missense variants in CR1 are associated with increased risk of Alzheimer' disease in Han Chinese
Ma, X., Yu, J., Tan, M., Sun, F.-R., Miao, D., & Tan, L. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.08.009 · Cited by 24
Two Alzheimer’s disease risk genes increase entorhinal cortex volume in young adults
DiBattista, A. M., Stevens, B. W., Rebeck, G. W., & Green, A. E. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00779 · Cited by 23
Schnetz‐Boutaud, N. C., Hoffman, J., Coe, J., Murdock, D. G., Pericak‐Vance, M. A., & Haines, J. L. (2012) · Annals of Human Genetics · doi:10.1111/j.1469-1809.2012.00727.x · Cited by 23
Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer’s Disease
Seripa, D., Panza, F., Paroni, G., D’Onofrio, G., Bisceglia, P., Gravina, C., Urbano, M., Lozupone, M., Solfrizzi, V., Bizzarro, A., et al. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0547-x · Cited by 21
Han, Z., Qu, J., Zhao, J., & Zou, X. (2018) · Scientific Reports · doi:10.1038/s41598-018-29450-2 · Cited by 22
Peripheral Pathways to Neurovascular Unit Dysfunction, Cognitive Impairment, and Alzheimer’s Disease
Nelson, A. R. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.858429 · Cited by 24
The "Alzheimer's disease signature": potential perspectives for novel biomarkers
Davinelli, S., Intrieri, M., Russo, C., Costanzo, A. D., Zella, D., Bosco, P., & Scapagnini, G. (2011) · Immunity & Ageing · doi:10.1186/1742-4933-8-7 · Cited by 22
Lessons from genome‐wide association studies findings in Alzheimer's disease
Moraes, C. F., Lins, T. C. D. L., CARMARGOS, E. F., Naves, J. O. S., Pereira, R. W., & Nóbrega, O. D. T. (2011) · Psychogeriatrics · doi:10.1111/j.1479-8301.2011.00378.x · Cited by 19
Zhu, X., Dai, W.-Z., & Ma, T. (2020) · BMC Medical Genetics · doi:10.1186/s12881-020-01114-x · Cited by 20
Genetic association of complement receptor 1 polymorphism rs3818361 in Alzheimer's disease
Antúnez, C., Boada, M., López‐Arrieta, J., Moreno‐Rey, C., Hernández, I., Marín, J., Gayán, J., Initiative, A. D. N., González‐Pérez, A., Real, L. M., et al. (2011) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2011.05.2412 · Cited by 20
Qin, X. Y., Peng, Q., Zeng, Z., Chen, Z., Lin, L., Deng, Y., Huang, X., Xu, J., Wu, H., Huang, S., et al. (2012) · Journal of Neurology · doi:10.1007/s00415-011-6381-6 · Cited by 20
Impact ofPICALMandCLUon hippocampal degeneration
Yang, X., Li, J., Liu, B., Li, Y., & Jiang, T. (2016) · Human Brain Mapping · doi:10.1002/hbm.23183 · Cited by 22
Stevens, B. W., DiBattista, A. M., Rebeck, G. W., & Green, A. E. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.06.021 · Cited by 20
Saad, M., Brkanac, Z., & Wijsman, E. M. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12250 · Cited by 19
Implication of a Genetic Variant at PICALM in Alzheimer's Disease Patients and Centenarians
Piaceri, I., Bagnoli, S., Lucenteforte, E., Mancuso, M., Tedde, A., Siciliano, G., Piacentini, S., Bracco, L., Sorbi, S., & Nacmias, B. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-101791 · Cited by 18
Association of aBACE1Gene Polymorphism with Parkinson’s Disease in a Norwegian Population
Lange, J., Lunde, K. A., Sletten, C., Møller, S. G., Tysnes, O., Alves, G. W., Larsen, J. P., & Maple‐Grødem, J. (2015) · Parkinson s Disease · doi:10.1155/2015/973298 · Cited by 18
Du, W., Tan, J., Xu, W., Chen, J., & Wang, L. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3734 · Cited by 17
Sapkota, S., & Dixon, R. A. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170909 · Cited by 20
Kong, C., Xie, H., Gao, Z., Shao, M., Li, H., Shi, R., Cai, L., Gao, S., Sun, T., & Li, C. (2019) · Virologica Sinica · doi:10.1007/s12250-019-00124-1 · Cited by 18
Genetic association between clusterin polymorphisms and Alzheimer's disease in a Japanese population
Komatsu, M., Shibata, N., Kuerban, B., Ohnuma, T., Baba, H., & Arai, H. (2011) · Psychogeriatrics · doi:10.1111/j.1479-8301.2010.00346.x · Cited by 17
Balcar, V. J., Zeman, T., Janout, V., Janoutová, J., Lochman, J., & Šerý, O. (2021) · Neurochemical Research · doi:10.1007/s11064-020-03176-y · Cited by 17
Yuan, Q., Chu, C., & Jia, J. (2011) · Neurological Sciences · doi:10.1007/s10072-011-0881-0 · Cited by 18
Association of MTHFR and PICALM polymorphisms with Alzheimer’s disease
Belcavello, L., Camporez, D., Almeida, L. D., Morelato, R. L., Batitucci, M. C. P., & Paula, F. (2014) · Molecular Biology Reports · doi:10.1007/s11033-014-3806-1 · Cited by 15
Patel, A., Rees, S. D., Kelly, M. A., Bain, S. C., Barnett, A. H., Prasher, A., Arshad, H., & Prasher, V. P. (2014) · BMC Research Notes · doi:10.1186/1756-0500-7-42 · Cited by 15
Genetic Complexity of Early-Onset Alzheimer’s Disease
Ghani, M., Reitz, C., George‐Hyslop, P. S., & Rogaeva, E. A. (2018) · Springer eBooks · doi:10.1007/978-3-319-72938-1_3 · Cited by 15
The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum
Xu, W., Wang, H.-F., Tan, L., Tan, M., Tan, C.-C., Zhu, X., Miao, D., Yu, W.-J., Jiang, T., Tan, L., et al. (2016) · Scientific Reports · doi:10.1038/srep24480 · Cited by 14
Self-citationA novel mouse model expressing human forms for complement receptors CR1 and CR2
Jackson, H. M., Foley, K. E., O’Rourke, R., Stearns, T. M., Fathalla, D., Morgan, B. P., & Howell, G. R. (2020) · BMC Genetics · doi:10.1186/s12863-020-00893-9 · Cited by 14
Extracellular chaperone networks and the export of J-domain proteins
Braun, J. E. A. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102840 · Cited by 15
Simmons, C. R., Zou, F., Younkin, S. G., & Estus, S. (2011) · Molecular Neurodegeneration · doi:10.1186/1750-1326-6-62 · Cited by 16
Self-citationCho, S. B. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042211 · Cited by 12
Zou, F., Belbin, O., Carrasquillo, M. M., Culley, O. J., Hunter, T. A., Ma, L., Bisceglio, G. D., Allen, M., Dickson, D. W., Graff‐Radford, N. R., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064802 · Cited by 13
Self-citationInfluence of PICALM and CLU risk variants on beta EEG activity in Alzheimer’s disease patients
Maturana-Candelas, A., Gómez, C., Poza, J., Rodríguez-González, V., Pablo, V. G.-D., Lopes, A. M., Pinto, N., & Hornero, R. (2021) · Scientific Reports · doi:10.1038/s41598-021-99589-y · Cited by 12
Common variant in GAB2 is associated with late-onset Alzheimer's disease in Han Chinese
Zhong, X.-L., Yu, J., Gui-ying, H., Xing, Y.-Y., Jiang, H. F., Li, Y., & Tan, L. (2010) · Clinica Chimica Acta · doi:10.1016/j.cca.2010.11.022 · Cited by 12
Blood–Brain Barrier Transport of Alzheimer’s Amyloid β-Peptide
Nelson, A. R., Sagare, A. P., & Zloković, B. V. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802173-6.00009-5 · Cited by 12
Association of LRRTM3 polymorphisms with late-onset Alzheimer's disease in Han Chinese
Wang, J., Yu, J., Jiang, T., Tan, M., Wang, H.-F., Tan, L., Hu, N., Sun, L., Zhang, W., & Tan, L. (2014) · Experimental Gerontology · doi:10.1016/j.exger.2014.01.013 · Cited by 11
Aghajanpour-Mir, M., Amjadi‐Moheb, F., Dadkhah, T., Hosseini, S. R., Ghadami, E., Assadollahi, E., Akhavan‐Niaki, H., & Ahangar, A. A. (2018) · Molecular Biology Reports · doi:10.1007/s11033-018-4561-5 · Cited by 12
Investigating Statistical Epistasis in Complex Disorders
Turton, J. C., Bullock, J. M., Medway, C., Shi, H., Brown, K. S., Belbin, O., Kalsheker, N. A., Carrasquillo, M. M., Dickson, D. W., Graff‐Radford, N. R., et al. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-110197 · Cited by 11
Self-citationExplore the role of CR1 genetic variants in late-onset Alzheimer’s disease susceptibility
Lu, L., Yao, Q.-Y., Ruan, S.-S., Hu, J.-W., Long, W.-J., Dai, W.-Z., Ma, T., & Zhu, X.-C. (2021) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000291 · Cited by 11
Takatori, S., & Tomita, T. (2018) · Advances in experimental medicine and biology · doi:10.1007/5584_2018_218 · Cited by 10
Giau, V. V., & An, S. S. A. (2015) · BioChip Journal · doi:10.1007/s13206-015-9306-8 · Cited by 10
Sohrabifar, N., Gharesouran, J., Talebi, M., Ghojazadeh, M., & Ardebili, S. M. M. (2015) · TURKISH JOURNAL OF MEDICAL SCIENCES · doi:10.3906/sag-1406-64 · Cited by 9
TrkB Isoforms Differentially Affect AICD Production through Their Intracellular Functional Domains
Ansaloni, S., Leung, B. C. L., Sebastian, N. P., Samudralwar, R. D., Gadaleta, M. C., & Saunders, A. J. (2011) · International Journal of Alzheimer s Disease · doi:10.4061/2011/729382 · Cited by 9
Epigenetic processes in Alzheimer's disease
Castanho, I., & Lunnon, K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813796-3.00008-0 · Cited by 10
GenoRisk: A polygenic risk score for Alzheimer's disease
Dickson, S. P., Hendrix, S. B., Brown, B. L., Ridge, P. G., Nicodemus‐Johnson, J., Hardy, M. L., McKeany, A. M., Booth, S. B., Fortna, R. R., Kauwe, J. S. K., et al. (2021) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.12211 · Cited by 8
Autosomal Dominant Alzheimer’s Disease: Underlying Causes
Ghani, M., & Rogaeva, E. A. (2014) · Springer eBooks · doi:10.1007/978-1-4471-6380-0_3 · Cited by 8
Ma, S. L., & LAM, L. C. W. (2011) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2011.9.2.54 · Cited by 8
Zhang, H., Zheng, W., Hua, L., Wang, Y., Li, J., Bai, H., Wang, S., Du, M., Ma, X., Xu, C., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.15691 · Cited by 7
Bai, F., Shi, Y., Yuan, Y., Xie, C., & Zhang, Z. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.02.015 · Cited by 7
Abdi, S., Alghamdi, A. A., AlGhunaim, N. N. A., Almutairi, R. M., Ataya, F. S., Ansari, M. G. A., Hussain, S. D., Masoud, M. S., Alamro, A. A., Almutairi, O. T., et al. (2022) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201023666220208093919 · Cited by 7
Пономарева, Н. В., Андреева, Т. В., Протасова, М. А., Filippova, Y. V., Kolesnikova, E. P., Fokin, V. F., Illarioshkin, S. N., & Rogaev, E. I. (2018) · Biochemistry (Moscow) · doi:10.1134/s0006297918090092 · Cited by 6
Jones, L., Holmans, P., Hamshere, M. L., Harold, D. H., Moskvina, V., Ivanov, D. K., Pocklington, A. J., Abraham, R., Hollingworth, P., Sims, R., et al. (2011) · PLoS ONE · doi:10.1371/annotation/a0bb886d-d345-4a20-a82e-adce9b047798 · Cited by 6
Self-citationDementia key gene identification with multi-layered SNP-gene-disease network
Lee, D. A., Kim, M.-J., Son, S. J., Hong, C. H., & Shin, H. (2020) · Bioinformatics · doi:10.1093/bioinformatics/btaa814 · Cited by 5
The Implications of Genomics on the Nursing Care of Adults With Neuropsychiatric Conditions
Schutte, D. L., Davies, M. A., & Goris, E. D. (2013) · Journal of Nursing Scholarship · doi:10.1111/jnu.12006 · Cited by 5
From Molecule to Clinic and Community for Neurodegeneration: Research to Bridge Translational Gaps
Brayne, C., Barker, R. A., Harold, D. H., Ince, P. G., Savva, G. M., Williams, J. H., Williams‐Gray, C. H., & Wharton, S. B. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-129006 · Cited by 5
Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease
Simmons, C. R., Zou, F., Younkin, S. G., & Estus, S. (2011) · Molecular Neurodegeneration · doi:10.1186/1750-1326-6-33 · Cited by 5
Self-citationGenetic variant rs11136000 upregulates clusterin expression and reduces Alzheimer’s disease risk
Ma, J., & Qiu, S. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.926830 · Cited by 5
Ji, W., Xu, L., Zhou, H., Wang, S., & Fang, Y. (2015) · PubMed · Cited by 5
Genetics of A lzheimer's Disease
Brookes, K. J., & Morgan, K. (2017) · Wiley eBooks · doi:10.1002/9780470015902.a0020228.pub2 · Cited by 6
Self-citationThe role of amyloid beta 4-42 in the etiology of Alzheimer's disease
Bouter, Y. (2015) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-4849 · Cited by 5
Aziz, M. A., Ashraf, G. M., & Islam, M. S. (2022) · Current Alzheimer Research · doi:10.2174/1567205019666220511140955 · Cited by 4
Genetic Risk Factors for Dementia
Hollingworth, P., & Williams, J. H. (2011) · Wiley eBooks · doi:10.1002/9781444344110.ch6 · Cited by 4
Zhu, B., Li, L., Zhang, L., Yang, S., Tian, Y., Guo, S., Zhang, W., & Zhao, Z. (2018) · Metabolic Brain Disease · doi:10.1007/s11011-018-0291-6 · Cited by 2
The Role of the Progesterone Receptor Family in Alzheimer’s Disease
Zhu, T., & Hua, F. (2025) · Biocell · doi:10.32604/biocell.2025.064879 · Cited by 1
Genetic Risk Factors: Their Function and Comorbidities in Alzheimer′s Disease
Hiltunen, M. O., Bertram, L., & Saunders, A. J. (2011) · International Journal of Alzheimer s Disease · doi:10.4061/2011/925362 · Cited by 1
Chen, L. H., Kao, P. Y. P., Fan, Y., Ho, D. T. Y., Chan, S. Y., Yik, P. Y., Ha, J. C. T., Chu, L., & Song, Y. (2011) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2011.05.498 · Cited by 1
Complement Component (3b/4b) Receptor 1 (CR1)
Lord, J., & Morgan, K. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7309-1_5 · Cited by 1
Self-citationPerna, S., Bologna, C., Cavagna, P., Bernardinelli, L., Guido, D., Peroni, G., & Rondanelli, M. (2016) · Genetika · doi:10.2298/gensr1602515p · Cited by 1
Pharmacogenomics and Personalized Medicine in Alzheimer’s Disease
Archer, T., & Johansson, B. E. A. (2013) · Springer eBooks · doi:10.1007/978-81-322-1184-6_15 · Cited by 1
Lord, J., & Morgan, K. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7309-1_3 · Cited by 1
Self-citationSex effects in predictors of memory resilience for carriers of Alzheimer’s genetic risk
McDermott, K. L. (2016) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3st7f49f · Cited by 1
Algamdi, A. A., Abdi, S., Almutairi, R. M., Sarwar, S., Aldaghri, N., Haq, S. H., Alamro, A. A., & Muayqil, T. A. (2021) · Research Square · doi:10.21203/rs.3.rs-287829/v1 · Cited by 1
Alzheimer’s Disease Genomics and Clinical Applications
Lee, T.-S. W., & Sian, M. (2011) · InTech eBooks · doi:10.5772/18773
Simmons, C. R. (2011) · UKnowledge (University of Kentucky)
Further insights into Alzheimer's disease
Sims, R., Gerrish, A., & Williams, J. H. (2012) · Quality in Ageing and Older Adults · doi:10.1108/14717791211264043
P2‐030: INVESTIGATING THE ROLE OF CLU, PICALM, AND CR1 IN ALZHEIMER'S DISEASE
Lord, J., Turton, J. C., Braae, A., Barber, I., Medway, C., Brown, K. S., & Morgan, K. (2014) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2014.05.703
Self-citationGenetica delle demenze degenerative
Wallon, D., & Nicolas, G. (2015) · EMC - Neurologia · doi:10.1016/s1634-7072(15)73962-0
The role of Kat2a during memory formation and chromatin plasticity in the aging murine hippocampus
Stilling, R. M. (2013) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-3945
Characterising the role of CR1 and CR2 in a humanised mouse model
Williams, H. M. (2016) · ORCA Online Research @Cardiff (Cardiff University)
Screening and evaluation of natural compounds for therapeutic application in Alzheimer's disease
Nirvanashetty, S. (2024) · Swinburne figshare (Swinburne University of Technology) · doi:10.25916/sut.26278636
Genomika obrazowa: nowy trend w badaniach nad chorobą Alzheimera
Dzianok, P. (2020) · Kosmos · doi:10.36921/kos.2020_2636
Metadata
- Authors
- Carrasquillo, M. M., Belbin, O., Hunter, T. A., Ma, L., Bisceglio, G. D., Zou, F., Crook, J. E., Pankratz, V. S., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Morgan, K., & Younkin, S. G.
- Affiliations
- Mayo Clinic in Florida (US)
- Mayo Clinic (US)
- University of Nottingham (GB)
- ORCID
- Venue
- Archives of Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 2010-08-01
- Volume
- 67
- Issue
- 8
- Pages
- 961-4
- ISSN
- 0003-9942 (ISSN-L)
- PMC
- PMC2919638
- OpenAlex
- W2065929647
- Cited by
- 208
- References
- 24
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 1 · 2022: 7 · 2021: 6 · 2020: 11 · 2019: 5 · 2018: 15 · 2017: 8 · 2016: 17 · 2015: 13 · 2014: 23 · 2013: 23 · 2012: 29
- FWCI
- 20.80
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Archives of Neurology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (U01 AG 06576, P50‐AG16574, AG03949, R01AG018023, U01AG006786, P01AG003949, AG 25711, R01-AG18023, AG 17216, U24 AG21886, P50AG025711, P01AG017216, U24AG021886, P50AG016574)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- Alzheimer's disease, late-onset Alzheimer's disease, CLU gene, genetic association, single nucleotide polymorphisms, genetic risk factors, replication study
- MeSH terms
- Alzheimer Disease, Follow-Up Studies, Gene Frequency, Genotype, Humans, Residence Characteristics, Odds Ratio, Case-Control Studies, Receptors, Complement 3b, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide, Monomeric Clathrin Assembly Proteins, White People, Clusterin, Genome-Wide Association Study
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review