Do We Have a Nutritional Treatment for Age-Related Cataract or Macular Degeneration?
Abstract
Age-related cataract and age-related macular degeneration are the major causes of visual impairment and blindness in the aging US population.1,2Because the elderly are the fastest-growing segment of the population, the prevalence of both disorders will rise dramatically in the next two decades. No medical treatment has been documented to prevent the development or slow the progression of either disease. Once cataracts have developed, surgical treatment is very effective, but cataract surgery, like all surgery, carries some risks and is imposing a growing economic burden on medical resources. Although some persons with the neovascular form of macular degeneration can benefit from laser photocoagulation,3no treatment is available for atrophic macular degeneration, by far the more common form of the disease. Animal research and preliminary epidemiologic studies have suggested a protective role for certain micronutrients in the development of cataract and macular degeneration, in particular, vitamins and certain trace
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Despite the lack of convincing evidence, the marketing and use of antioxidants and zinc in eye-targeted formulations has become a common practice.
“Despite the lack of convincing evidence, the marketing and use of antioxidants and zinc in eye-targeted formulations has become a common practice.30”
Cites
Oral Zinc in Macular Degeneration
Newsome, D. A., Swartz, M., Leone, N. C., Elston, R. C., & Miller, E. (1988) · Archives of Ophthalmology · doi:10.1001/archopht.1988.01060130202026 · Cited by 349 · see citing works
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(2001) · Archives of Ophthalmology · doi:10.1001/archopht.119.10.1417 · Cited by 3,285 · see citing works
The Role of Oxidative Stress in the Pathogenesis of Age-Related Macular Degeneration
Beatty, S., Koh, H.-H., Phil, M., Henson, D., & Boulton, M. (2000) · Survey of Ophthalmology · doi:10.1016/s0039-6257(00)00140-5 · Cited by 2,051 · see citing works
Nutrition, Well-Being and Health
(2012) · doi:10.5772/1864 · Cited by 178 · see citing works
- Authors
- Sperduto, R. D.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Sperduto, Robert D.
- Venue
- Archives of Ophthalmology
- Publisher
- American Medical Association (AMA)
- Published
- 1990-10-01
- Volume
- 108
- Issue
- 10
- Pages
- 1403
- ISSN
- 0003-9950 (ISSN-L)
- OpenAlex
- W2153453628
- Cited by
- 65
- References
- 1
- Citations by year
- 2021: 3 · 2019: 1 · 2016: 2 · 2015: 2 · 2012: 4
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Ophthalmology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Keywords
- senile cataract, age-related macular degeneration, nutritional therapy, micronutrients, vitamins, trace elements, atrophic macular degeneration, neovascular age-related macular degeneration, visual impairment, cataract surgery
- MeSH terms
- Aging, Animals, Cataract, Humans, Macular Degeneration, Minerals, Vitamins
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