The DOI matches its Crossref record; 90 of the 90 references it cites were found in a registry or an index.
Dry Eye Disease: An Immune-Mediated Ocular Surface Disorder
Open accessAbstract
Dry eye disease is a multifactorial disorder of the tears and ocular surface characterized by symptoms of dryness and irritation. Although the pathogenesis of dry eye disease is not fully understood, it is recognized that inflammation has a prominent role in the development and propagation of this debilitating condition. Factors that adversely affect tear film stability and osmolarity can induce ocular surface damage and initiate an inflammatory cascade that generates innate and adaptive immune responses. These immunoinflammatory responses lead to further ocular surface damage and the development of a self-perpetuating inflammatory cycle. Herein, we review the fundamental links between inflammation and dry eye disease and discuss the clinical implications of inflammation in disease management.
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Cites
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(2007) · The Ocular Surface · doi:10.1016/s1542-0124(12)70082-4 · Cited by 1,227
Prevalence of dry eye syndrome among US women
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Corneal nerves: structure, contents and function
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Dietary polyunsaturated fatty acids and inflammatory mediator production
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Impact of Dry Eye Syndrome on Vision-Related Quality of Life
Miljanović, B., Dana, R., Sullivan, D. A., & Schaumberg, D. A. (2007) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2006.11.060 · Cited by 838
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Cited by
Neuropeptide substance P and the immune response
Mashaghi, A., Marmalidou, A., Tehrani, M., Grace, P. M., Pothoulakis, C., & Dana, R. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2293-z · Cited by 493
Inflammation in Glaucoma: From the back to the front of the eye, and beyond
Baudouin, C., Kolko, M., Melik-Parsadaniantz, S., & Messmer, E. M. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100916 · Cited by 454
In Vivo Confocal Microscopy of Corneal Nerves in Health and Disease
Cruzat, A., Qazi, Y., & Hamrah, P. (2017) · The Ocular Surface · doi:10.1016/j.jtos.2016.09.004 · Cited by 364
The Core Mechanism of Dry Eye Disease Is Inflammation
Wei, Y., & Asbell, P. A. (2014) · Eye & Contact Lens: Science & Clinical Practice · doi:10.1097/icl.0000000000000042 · Cited by 259
Therapeutic Effect of MK2 Inhibitor on Experimental Murine Dry Eye
Wu, Y., Bu, J., Yang, Y., Lin, X., Cai, X., Huang, C., Zheng, X., Ouyang, W., Li, W., Zhang, X., et al. (2017) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.17-22240 · Cited by 12
Metadata
- Authors
- Stevenson, W.
- Venue
- Archives of Ophthalmology
- Publisher
- American Medical Association (AMA)
- Published
- 2012-01-01
- Volume
- 130
- Issue
- 1
- Pages
- 90
- ISSN
- 0003-9950 (ISSN-L)
- OpenAlex
- W2073200435
- Cited by
- 583
- References
- 90
- FWCI
- 30.09
- Type
- journal article
- Language
- en
- Open access
- green
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
