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Otitis Media: Clinical Observations, Microbiology, and Evaluation of Therapy
Abstract
ACUTE otitis media is a common problem in infants and children. Although antibiotics seem to be effective in controlling suppurative complications, otitis is still a significant cause of morbidity and hearing loss. The etiology remains unsettled and treatment is largely empirical. Bacteriologic studies have repeatedly demonstrated that in only 60% to 70% of cases is it possible to isolate a pathogen from middle ear fluid.1-5Unproved explanations for the sterility of the remaining 30% to 40% are diverse and include a possible viral etiology.5There have been only sporadic accounts of virus isolation from middle ear fluid; few systematic attempts to isolate virus from middle ear fluid have been reported.5-8The association ofMycoplasmawith bullous myringitis has been observed in adult volunteers infected with artificially propagatedM pneumoniae.9In naturally acquiredMpneumoniaeinfection the organism has been recovered on several occasions from the middle
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Cited by
The Diagnosis and Management of Acute Otitis Media
Lieberthal, A. S., Carroll, A. E., Chonmaitree, T., Ganiats, T. G., Hoberman, A., Jackson, M. A., Joffe, M. D., Miller, D. T., Rosenfeld, R. M., Sevilla, X. D., et al. (2013) · Pediatrics · doi:10.1542/peds.2012-3488 · Cited by 1,442
Natural history of untreated otitis media
Rosenfeld, R. M., & Kay, D. (2003) · The Laryngoscope · doi:10.1097/00005537-200310000-00004 · Cited by 428
Henderson, F. W., Collier, A. M., Sanyal, M. A., Watkins, J. M., Fairclough, D. L., Clyde, W. A., & Denny, F. W. (1982) · New England Journal of Medicine · doi:10.1056/nejm198206103062301 · Cited by 393
The role of respiratory viruses in otitis media
Heikkinen, T. (2000) · Vaccine · doi:10.1016/s0264-410x(00)00278-4 · Cited by 53
Metadata
- Authors
- Halsted, C.
- Venue
- American Journal of Diseases of Children
- Publisher
- American Medical Association (AMA)
- Published
- 1968-05-01
- Volume
- 115
- Issue
- 5
- Pages
- 542
- ISSN
- 0002-922X (ISSN-L)
- OpenAlex
- W2139664065
- Cited by
- 163
- References
- 0
- FWCI
- 18.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Halsted, C. (1968). Otitis Media: Clinical Observations, Microbiology, and Evaluation of Therapy. American Journal of Diseases of Children. https://doi.org/10.1001/archpedi.1968.02100010544003
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