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Cited by 42Schizophrenia research and treatmentMental Health and PsychiatryPsychoanalysis and Psychopathology Research

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Schizophrenia and Arousal Revisited: Two-Flash Thresholds and Electrodermal Activity in Activated and Nonactivated Conditions

Gruzelier, John H.·1972·Archives of General Psychiatry
DOI 10.1001/archpsyc.1972.01750230037007
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Abstract

The relation between two-flash thresholds (TFTs) and electrodermal activity—skin conductance level (SCL) and skin potential level (SPL), of paranoid and nonparanoid schizophrenics and normal controls was examined in activated and nonactivated conditions. A bicycle ergometer which induced significant changes in heart rate was used as an activator. At low levels of skin potential and skin conductance the two-flash thresholds of the controls were positively related to skin potential and skin conductance whereas at higher levels of skin potential and skin conductance, and in activated conditions, a negative relation was found. In general the two-flash thresholds of both schizophrenic groups were negatively related to skin potential and skin conductance in nonactivated conditions; when activated the paranoids showed the same changes as normals while the nonparanoids showed raised two-flash thresholds and lowered skin conductance levels. These findings are interpreted as showing the operation of inhibitory processes, consonant with the concept of protective inhibition, elicited as somatic arousal increases in nonparanoid but not paranoid schizophrenics.

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Crossref · 10.1001/archpsyc.1972.01750230037007

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28 of 28 references verified0 citation errors · 0 not checkable

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  • Approximately 40-60% of the schizophrenia population has been classified as electrodermal activity non-responders, substantially greater than the proportion of healthy individuals who are non-responders.

    “Approximately 40–60% of the SCZ population has been classified as EDA non-responders gave their significantly suppressed skin conductance in response to noxious stimuli40,41; this is substantially greater than the proportion of healthy individuals that are EDA non-responders39.”

    From Autonomic nervous system dysfunction in schizophrenia: impact on cognitive and metabolic health (2021) · cites this paper as [39]

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Metadata

Authors
Gruzelier, J. H.
Corresponding author
Gruzelier, John H.
Venue
Archives of General Psychiatry
Publisher
American Medical Association (AMA)
Published
1972-05-01
Volume
26
Issue
5
Pages
427
ISSN
0003-990X (ISSN-L)
DOI
10.1001/archpsyc.1972.01750230037007
OpenAlex
W2079292066
Cited by
42
References
28
Citations by year
2021: 1
FWCI
9.73
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of General Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
schizophrenia, paranoid schizophrenia, electrodermal activity, skin conductance level, somatic arousal, inhibitory processes, cycle ergometer
MeSH terms
Adult, Arousal, Diagnosis, Differential, Differential Threshold, Electrophysiology, Physical Exertion, Galvanic Skin Response, Heart Rate, Hippocampus, Humans, Inhibition, Psychological, Light, Male, Muscle Contraction, Paranoid Disorders, Psychophysics, Schizophrenia, Skin Physiological Phenomena, Visual Perception

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