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Cited by 342

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Diagnosis and Treatment of Minimal Brain Dysfunction in Adults: A Preliminary Report

Wood, David R.·1976·Archives of General Psychiatry

Abstract

Minimal brain dysfunction (MBD) has long been considered a disorder limited to childhood. A number of longitudinal and adoption studies suggest that MBD may persist into adult life where its existence is concealed by the application of a variety of diagnostic labels. In order to test the hypothesis that MBD does persist into adulthood, 15 putative MBD adults were identified on the basis of current MBD-like complaints, self-description of MBD characteristics in childhood, and a parental rating (on a standardized form) of "hyperactivity" in childhood. Eleven of the 15 subjects were given a double-blind trial of methylphenidate hydrochloride, and all 15 were given an open trial of pemoline, imipramine hydrochloride, or amitryptiline hydrochloride. Eight of the 11 showed a significant response to the double-blind trial of methylphenidate. Of the 15, eight showed a good response to stimulants or tricyclic antidepressants, two showed a moderately favorable response, and five were unresponsive to drug therapy.

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Metadata

Authors
Wood, D. R.
Venue
Archives of General Psychiatry
Published
1976-12-01
Volume
33
Issue
12
Pages
1453
ISSN
0003-990X (ISSN-L)
OpenAlex
W1974936217
Cited by
342
References
30
FWCI
11.78
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Diagnosis and Treatment of Minimal Brain Dysfunction in Adults: A Preliminary Report. https://app.cochat.ai/papers/10.1001/archpsyc.1976.01770120057005
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Wood, D. R. (1976). Diagnosis and Treatment of Minimal Brain Dysfunction in Adults: A Preliminary Report. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1976.01770120057005

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