The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Seizure Threshold in Electroconvulsive Therapy: Effects of Sex, Age, Electrode Placement, and Number of Treatments
Abstract
In a random-assignment trial to unilateral right and bilateral electrode placements, electroconvulsive therapy (ECT) stimulus intensity was titrated to just above seizure threshold for each of 52 depressed patients. Seizure threshold was quantified in units of charge. There was a 12-fold range in the minimum electrical intensity necessary to produce seizure. Sex, age, electrode placement, and the cumulative number of treatments were each associated with seizure threshold. Bilateral ECT had both a higher initial seizure threshold and a greater cumulative increase in seizure threshold compared with unilateral ECT. Clinical and research implications are discussed with respect to dosing strategies in ECT.
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Citations
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Cited by
Sackeim, H. A., Prudic, J., Devanand, D. P., Kiersky, J. E., Fitzsimons, L., Moody, B. J., McElhiney, M. C., Coleman, E. A., & Settembrino, J. M. (1993) · New England Journal of Medicine · doi:10.1056/nejm199303253281204 · Cited by 940
Self-citationReport by the ACNP Task Force on Response and Remission in Major Depressive Disorder
Rush, A. J., Kraemer, H. C., Sackeim, H. A., Fava, M., Trivedi, M. H., Frank, E., Ninan, P. T., Thase, M. E., Gelenberg, A. J., Kupfer, D. J., et al. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301131 · Cited by 707
Self-citationSackeim, H. A., Haskett, R. F., Mulsant, B. H., Thase, M. E., Mann, J. J., Pettinati, H. M., Greenberg, R. M., Crowe, R. R., Cooper, T. B., & Prudic, J. (2001) · JAMA · doi:10.1001/jama.285.10.1299 · Cited by 686
The cognitive effects of electroconvulsive therapy in community settings
Sackeim, H. A., Prudic, J., Fuller, R., Keilp, J., Lavori, P. W., & Olfson, M. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301180 · Cited by 577
Sackeim, H. A., Prudic, J., Nobler, M. S., Fitzsimons, L., Lisanby, S. H., Payne, N., Berman, R. M., Brakemeier, E.-L., Perera, T., & Devanand, D. P. (2008) · Brain Stimulation · doi:10.1016/j.brs.2008.03.001 · Cited by 542
Metadata
- Authors
- Sackeim, H.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1987-04-01
- Volume
- 44
- Issue
- 4
- Pages
- 355
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2010423644
- Cited by
- 333
- References
- 1
- FWCI
- 7.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Seizure Threshold in Electroconvulsive Therapy: Effects of Sex, Age, Electrode Placement, and Number of Treatments. https://app.cochat.ai/papers/10.1001/archpsyc.1987.01800160067009
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- Sackeim, H. (1987). Seizure Threshold in Electroconvulsive Therapy: Effects of Sex, Age, Electrode Placement, and Number of Treatments. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1987.01800160067009
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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