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Cited by 503

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

A Structured Psychiatric Intervention for Cancer Patients: II. Changes Over Time in Immunological Measures

Fawzy, Fawzy I.·1990·Archives of General Psychiatry

Abstract

We evaluated the immediate and long-term effects on immune function measures of a 6-week structure psychiatric group intervention for patients with malignant melanoma. Along with a reduction in levels of psychological distress and greater use of active coping methods, the following immune changes were seen at the 6-month assessment point in the intervention-group patients (n = 35) compared with controls (n = 26): significant increases in the percent of large granular lymphocytes (defined as CD57 with Leu-7) and natural killer (NK) cells (defined as CD16 with Leu-11 and CD56 with NKH1) along with indications of increase in NK cytotoxic activity; and a small decrease in the percent of CD4 (helper/inducer) T cells. At the 6-week follow-up point, the majority of these changes were not yet observable. The results indicate that a short-term psychiatric group intervention in patients with malignant melanoma with a good prognosis was associated with longer-term changes in affective state, coping, and the NK lymphoid cell system. Affective rather than coping measures showed some significant correlations with immune cell changes.

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Metadata

Authors
Fawzy, F. I.
Venue
Archives of General Psychiatry
Published
1990-08-01
Volume
47
Issue
8
Pages
729
ISSN
0003-990X (ISSN-L)
OpenAlex
W2138576434
Cited by
503
References
30
FWCI
14.25
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Structured Psychiatric Intervention for Cancer Patients: II. Changes Over Time in Immunological Measures. https://app.cochat.ai/papers/10.1001/archpsyc.1990.01810200037005
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Fawzy, F. I. (1990). A Structured Psychiatric Intervention for Cancer Patients: II. Changes Over Time in Immunological Measures. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1990.01810200037005

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