The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Enhanced Sensitivity to Cholecystokinin Tetrapeptide in Panic Disorder: Clinical and Behavioral Findings
Abstract
We studied the action of cholecystokinin tetrapeptide (CCK-4) in patients with panic disorder and normal controls. Subjects received, in random order, one injection of CCK-4 and one injection of placebo (saline) on two separate days in a double-blind crossover design. Two doses of CCK-4, 50 and 25 micrograms, were administered to two different samples of subjects. The panic rate with 50 micrograms of CCK-4 was 100% (12/12) for patients and 47% (7/15) for controls. The panic rate with 25 micrograms of CCK-4 was 91% (10/11) for patients and 17% (2/12) for controls. Nine percent of patients compared with 0% of controls panicked with placebo. These findings concur with previous reports of a panicogenic effect of CCK-4 and suggest that patients with panic disorder are more sensitive to the panicogenic effect of the peptide than are normal controls.
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Cites
Clark, D. M. (1986) · Behaviour Research and Therapy · doi:10.1016/0005-7967(86)90011-2 · Cited by 2,422
Larsson, L.-I., & Rehfeld, J. F. (1979) · Brain Research · doi:10.1016/0006-8993(79)90554-7 · Cited by 663
Chang, R. S., & Lotti, V. J. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.13.4923 · Cited by 540
Cholecystokinin octapeptide-like immunoreactivity: histochemical localization in rat brain.
Innis, R. B., Corrêa, F. M., Uhl, G. R., Schneider, B., & Snyder, S. H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.521 · Cited by 451
Cholecystokinin Receptors in the Brain: Characterization and Distribution
Saito, A., Sankaran, H., Goldfine, I. D., & Williams, J. A. (1980) · Science · doi:10.1126/science.6246582 · Cited by 431
Charney, D. S., Heninger, G. R., & Redmond, D. E. (1983) · Life Sciences · doi:10.1016/0024-3205(83)90707-5 · Cited by 346
Skirboll, L. R., Grace, A. A., Hommer, D. W., Rehfeld, J., Goldstein, M., Hökfelt, T., & Bunney, B. S. (1981) · Neuroscience · doi:10.1016/0306-4522(81)90002-6 · Cited by 324
Cholecystokinin Tetrapeptide Induces Panic-like Attacks in Healthy Volunteers: Preliminary Findings
de Montigny, C. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810060031006 · Cited by 320
Distribution of neuropeptides in the limbic system of the rat: The amygdaloid complex
Roberts, G. W., Woodhams, P. L., Polak, J. M., & Crow, T. J. (1982) · Neuroscience · doi:10.1016/0306-4522(82)90156-7 · Cited by 312
Cholecystokinin-Tetrapeptide Induces Panic Attacks in Patients with Panic Disorder
Bradwejn, J., Koszycki, D., & Meterissian, G. (1990) · The Canadian Journal of Psychiatry · doi:10.1177/070674379003500115 · Cited by 293
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Cited by
Bandelow, B., Baldwin, D., Abelli, M., Bolea-Alamanac, B., Bourin, M., Chamberlain, S. R., Cinosi, E., Davies, S., Domschke, K., Fineberg, N., et al. (2017) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2016.1190867 · Cited by 347
Update on Bispectral Index monitoring
Johansen, J. W. (2006) · Best Practice & Research Clinical Anaesthesiology · doi:10.1016/j.bpa.2005.08.004 · Cited by 313
The etiology, biology, and evolving pathology of premenstrual syndromes
Halbreich, U. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(03)00097-0 · Cited by 306
Vialou, V., Bagot, R. C., Cahill, M. E., Ferguson, D., Robison, A. J., Dietz, D. M., Fallon, B., Mazei-Robison, M., Ku, S. M., Harrigan, E., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1787-13.2014 · Cited by 283
“Patients predisposed to panic attacks become hypersensitized after CCK exposure (de Montigny, 1989; Bradwejn et al., 1991).”
BackgroundBowers, M. E., Choi, D. C., & Ressler, K. J. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.03.004 · Cited by 155
Metadata
- Authors
- Bradwejn, J.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1991-07-01
- Volume
- 48
- Issue
- 7
- Pages
- 603
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2019683883
- Cited by
- 347
- References
- 36
- FWCI
- 6.71
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bradwejn, J. (1991). Enhanced Sensitivity to Cholecystokinin Tetrapeptide in Panic Disorder: Clinical and Behavioral Findings. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1991.01810310021005
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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