The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Magnetic Resonance Imaging Abnormalities in Lenticular Nuclei and Cerebral Cortex in Schizophrenia
Open accessAbstract
Neuropathologic and brain imaging studies have produced evidence of brain abnormalities in schizophrenic patients, often within the cerebrum's limbic lobe, and, less frequently, within basal ganglia. In the present study we used magnetic resonance imaging morphometric techniques to estimate volumes of specific cerebral structures in schizophrenic patients and age- and sex-matched normal controls. Estimates of the volume of mesial temporal lobe structures were reduced and estimates of the volume of the lenticular nucleus were increased in the schizophrenic patients. There was also evidence of reduced cranial volume in some schizophrenics. The magnitude of the lenticular abnormality, but not the temporal lobe abnormality, was associated with age at first psychiatric contact; earlier onset was associated with larger lenticular nuclei. The possible relevance of these results to neurodevelopmental hypotheses about the pathogenesis of schizophrenia is discussed.
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Cites
Implications of Normal Brain Development for the Pathogenesis of Schizophrenia
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Cited by
Casey, B. J., Jones, R. M., & Hare, T. A. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.010 · Cited by 3,345
A review of MRI findings in schizophrenia
Shenton, M. E., Dickey, C. C., Frumin, M., & McCarley, R. W. (2001) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00163-3 · Cited by 2,346
Basal ganglia and cerebellar loops: motor and cognitive circuits
Middleton, F. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00040-5 · Cited by 1,940
Casey, B. J., Getz, S., & Galvan, A. (2008) · Developmental Review · doi:10.1016/j.dr.2007.08.003 · Cited by 1,810
Meta-analysis of regional brain volumes in schizophrenia
Wright, I. C., Rabe-Hesketh, S., Woodruff, P. W. R., David, A. S., Murray, R. M., & Bullmore, E. T. (2000) · American Journal of Psychiatry · doi:10.1176/ajp.157.1.16 · Cited by 1,662
Metadata
- Authors
- Jernigan, T. L.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1991-10-01
- Volume
- 48
- Issue
- 10
- Pages
- 881
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W1964488079
- Cited by
- 266
- References
- 58
- FWCI
- 17.70
- Type
- journal article
- Language
- en
- Open access
- green
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- Jernigan, T. L. (1991). Magnetic Resonance Imaging Abnormalities in Lenticular Nuclei and Cerebral Cortex in Schizophrenia. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1991.01810340013002
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
