The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Reduced Caudate Nucleus Volume in Obsessive-compulsive Disorder
Abstract
BACKGROUND: Current hypotheses about the neuroanatomical structures involved in obsessive-compulsive disorder (OCD) suggest abnormalities in cortical-striatal-thalamic-cortical circuits. This study examined selected brain regions within or adjacent to these circuits. METHODS: Magnetic resonance imaging scans from 26 patients with OCD and 26 healthy controls were analyzed to determine the volumes of the following structures: prefrontal cortex (cortex anterior to the genu of the corpus callosum), caudate nucleus, lateral and third ventricles, and whole brain. RESULTS: Patients with OCD had significantly smaller caudate nucleus volumes than controls (F[1,48] = 9.4, P = .004) but did not differ in prefrontal cortex size or in volumes of the lateral or third ventricles. Structural volumes were not significantly correlated with the duration or severity of OCD symptoms. CONCLUSION: Our findings provide additional evidence for pathological involvement of the caudate in OCD.
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The assessment and analysis of handedness: The Edinburgh inventory
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Frontal-subcortical circuits and human behavior
Cummings, J. L. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540080076020 · Cited by 2,262
Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder
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Magnetic Resonance Imaging of the Caudate Nuclei in Depression: Preliminary Observations
Krishnan, K. R. R. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820070047007 · Cited by 365
(1988) · American Journal of Psychiatry · doi:10.1176/ajp.145.9.1089 · Cited by 284
Cited by
POSNER, J., RUSSELL, J. A., & PETERSON, B. S. (2005) · Development and Psychopathology · doi:10.1017/s0954579405050340 · Cited by 2,602
The Neurocircuitry of Fear, Stress, and Anxiety Disorders
Shin, L. M., & Liberzon, I. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.83 · Cited by 2,083
Basal ganglia and cerebellar loops: motor and cognitive circuits
Middleton, F. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00040-5 · Cited by 1,940
The Role of the Dorsal Striatum in Reward and Decision-Making: Figure 1.
Balleine, B. W., Delgado, M. R., & Hikosaka, O. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.1554-07.2007 · Cited by 1,390
Menzies, L., Chamberlain, S. R., Laird, A. R., Thelen, S. M., Sahakian, B. J., & Bullmore, E. T. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.09.005 · Cited by 1,190
Metadata
- Authors
- Robinson, D.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1995-05-01
- Volume
- 52
- Issue
- 5
- Pages
- 393
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W1991357403
- Cited by
- 320
- References
- 5
- FWCI
- 18.49
- Type
- journal article
- Language
- en
- Open access
- closed
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