Cited by 755Psychotherapy Techniques and ApplicationsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesChild and Adolescent Psychosocial and Emotional Development

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A Clinical Psychotherapy Trial for Adolescent Depression Comparing Cognitive, Family, and Supportive Therapy

Brent, David A.·1997·Archives of General Psychiatry

DOI 10.1001/archpsyc.1997.01830210125017

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Abstract

BACKGROUND: Previous studies in nonclinical samples have shown psychosocial treatments to be efficacious in the treatment of adolescent depression, but few psychotherapy treatment studies have been conducted in clinically referred, depressed adolescents. METHODS: One hundred seven adolescent patients with DSM-III-R major depressive disorder (MDD) were randomly assigned to 1 of 3 treatments: individual cognitive behavior therapy, systemic behavior family therapy (SBFT), or individual nondirective supportive therapy (NST). Treatments were 12 to 16 sessions provided in as many weeks. Intent-to-treat analyses were conducted using all follow-up data. RESULTS: Of the 107 patients enrolled in the study, 78 (72.9%) completed the study, 4 (3.7%) never initiated treatment, 10 (9.3%) had exclusionary criteria that were undetected at entry, 8 (7.5%) dropped out, and 7 (6.5%) were removed for clinical reasons. Cognitive behavior therapy showed a lower rate of MDD at the end of treatment compared with NST (17.1% vs 42.4%; P = .02), and resulted in a higher rate of remission (64.7%, defined as absence of MDD and at least 3 consecutive Beck Depression Inventory scores < 9) than SBFT (37.9%; P = .03) or NST (39.4%; p = .04). Cognitive behavior therapy resulted in more rapid relief in interviewer-rated (vs both treatments, P = .03) and self-reported depression (vs SBFT, P = .02). All 3 treatments showed significant and similar reductions in suicidality and functional impairment. Parents' views of the credibility of cognitive behavior therapy improved compared with parents' views of both SBFT (P = .01) and NST (P = .05). CONCLUSIONS: Cognitive behavior therapy is more efficacious than SBFT or NST for adolescent MDD in clinical settings, resulting in more rapid and complete treatment response.

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Klomek, A. B., Krispin, O., & Apter, A. (2009) · doi:10.1093/med/9780198570059.003.0086 · Cited by 3
Effective treatments for suicidal youth
Brent, D. A. (2009) · doi:10.1093/med/9780198570059.003.0091 · Cited by 3
Self-citation
Evidence-Based Psychosocial Treatments of Depression in Adolescents
Curry, J. F., & Meyer, A. E. (2020) · Issues in clinical child psychology · doi:10.1007/978-3-030-44226-2_9 · Cited by 3
Hintergründe und Entwicklung
Margraf, J. (2018) · Springer eBooks · doi:10.1007/978-3-662-54911-7_1 · Cited by 3
Depression in Adolescents: Current Treatments, Suicidality and Evaluation of Novel Treatment Strategies
Smajkic, A. (2009) · Bosnian Journal of Basic Medical Sciences · doi:10.17305/bjbms.2009.2768 · Cited by 3
The resourceful adolescent program: A universal approach to the prevention of depression in adolescents
Shochet, I. M., Montague, R., & Ham, D. (2002) · International perspectives on child and adolescent mental health · doi:10.1016/s1874-5911(02)80009-4 · Cited by 3
Efficacy of Treatments for Depression in Children and Adolescents
Carr, V., & Boyd, C. P. (2003) · Behaviour Change · doi:10.1375/bech.20.2.103.24842 · Cited by 3
“For example, research by Brent et al. (1997) examined the efficacy of a number of psychotherapies with 107 depressed adolescents.”
BackgroundInfluential
Brief Cognitive Therapy for Depressed and Suicidal Adolescents: A Critical Comment
Orbach, I. (1999) · Clinical Child Psychology and Psychiatry · doi:10.1177/1359104599004004014 · Cited by 4
“Brent et al. (1997) report that their cognitive-behavior therapy for depressed adolescents was superior to systematic family intervention and supportive therapy with respect to clinical recovery and symptomatic improvement, but not with respect to suicidality or functional status.”
Background
Social Demographics and Effective Management of Suicidal Thoughts among Adolescent Learners in Malawi: A Quasi Experimental Study, Southern Malawi
Kuyokwa, J., Banda, D. M., Chiziwa, S., & Semphere, N. (2024) · Journal of Humanities and Social Sciences Studies · doi:10.32996/jhsss.2024.6.3.5 · Cited by 2
“This is similar to what Brent et al. (1997) observed that there was a 1% reduction in the prevalence of suicidal thoughts among adolescents.”
Result
Family Therapy
Cottrell, D. J., Boston, P., & Walker, D. (2004) · Springer eBooks · doi:10.1007/978-3-642-18611-0_13 · Cited by 2
Nutzenbewertung des IQWiG für Systemische Therapie bei Kindern und Jugendlichen
von Sydow, K., Retzlaff, R., & Beher, S. (2024) · Kontext · doi:10.13109/kont.2024.55.2.137 · Cited by 2
Children and Adolescents
Bober, J. F., & Preskorn, S. (2004) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-18500-7_12 · Cited by 2
The relation between comorbid anxiety and treatment outcome in depressed early adolescent girls
Hamilton, A. M. (2009) · Texas ScholarWorks (Texas Digital Library) · Cited by 2
Pediatric depression
Brent, D. A. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139175869.011 · Cited by 2
Self-citation
Round of Applause for an Agenda and Regular Report Cards for Child and Adolescent Psychotherapy Research
Kendall, P. C. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.9.839 · Cited by 2
Antidepressant Treatment of Pediatric Depression
Vela, R. M., Glod, C. A., Rivinus, T. M., & Johnson, R. (2010) · Humana Press eBooks · doi:10.1007/978-1-60327-435-7_9 · Cited by 2
Mood Disorders in Children and Adolescents
Cullen, K. R., & Bortnova, A. (2016) · Springer eBooks · doi:10.1007/978-1-4939-2528-5_19 · Cited by 2
Antidepressivos e suicídio nos adolescentes.
Silva, M., & Sampaio, D. (2011) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.20344/amp.481 · Cited by 2
Suicide and attempted suicide in children and adolescents
Shaffer, D., Pfeffer, C. R., & Gutstein, J. (2012) · doi:10.1093/med/9780199696758.003.0221 · Cited by 2
Childhood Obesity: Depression, Anxiety and Recommended Therapeutic Strategies
Rofey, D. L., Black, J. J., Phillips, J. E., Blake, R., & Olson, K. L. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374995-6.10023-4 · Cited by 3
Psychoeducation with Caregivers of Older Adults
Gleason-Wynn, P. (2003) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195149524.003.0011 · Cited by 2
Cognitive Behavioral Therapy in Youth: An Update
Kennard, B., Mahoney, J. R., & Mayes, T. (2011) · Psychiatric Annals · doi:10.3928/00485713-20110325-06 · Cited by 3
Family Involvement in Psychotherapy
Manassis, K. (2005) · Elsevier eBooks · doi:10.1016/b978-008044449-9/50014-9 · Cited by 2

Authors: Brent, D. A.
Corresponding author: Brent, David A.
ORCID: Brent, David A.
Venue: Archives of General Psychiatry
Publisher: American Medical Association (AMA)
Published: 1997-09-01
Volume: 54
Issue: 9
Pages: 877
ISSN: 0003-990X (ISSN-L)
DOI: 10.1001/archpsyc.1997.01830210125017
OpenAlex: W1993925129
Cited by: 753
References: 58
Citations by year: 2025: 4 · 2024: 12 · 2023: 12 · 2022: 12 · 2021: 24 · 2020: 12 · 2019: 9 · 2018: 17 · 2017: 11 · 2016: 16 · 2015: 32 · 2014: 31 · 2013: 22 · 2012: 35
FWCI: 35.77
Type: journal article
Language: en
Open access: closed
Locations: Archives of General Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01mh046500-07)
National Institute of Mental Health (MH 46500)
Topics: Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords: adolescent depression, major depressive disorder, cognitive behavioral therapy, supportive therapy, family therapy, treatment efficacy, remission, suicidality, functional disability, parental attitudes
MeSH terms: Adolescent, Age Factors, Attitude to Health, Depressive Disorder, Family Therapy, Female, Humans, Male, Person-Centered Psychotherapy, Parents, Patient Dropouts, Social Class, Suicide, Comorbidity, Cognitive Behavioral Therapy, Treatment Outcome

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A Clinical Psychotherapy Trial for Adolescent Depression Comparing Cognitive, Family, and Supportive Therapy

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