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Cited by 170Prenatal Substance Exposure EffectsSubstance Abuse Treatment and OutcomesMaternal Mental Health During Pregnancy and Postpartum

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Causal Inferences Regarding Prenatal Alcohol Exposure and Childhood Externalizing Problems

D’Onofrio, Brian M., Van Hulle, Carol A., Waldman, Irwin D., Rodgers, Joseph Lee, Rathouz, Paul J., Lahey, Benjamin B.·2007·Archives of General Psychiatry
DOI 10.1001/archpsyc.64.11.1296
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Abstract

Context Existing research on the neurobehavioral consequences of prenatal alcohol exposure (PAE) has not adequately accounted for genetic and environmental confounds. Objective To examine the association between PAE and offspring externalizing problems in a large representative sample of families in the United States using measured covariates and a quasi-experimental design to account for unmeasured genetic and environmental confounds. Design This study combines information from the National Longitudinal Survey of Youth and the Children of the National Longitudinal Survey of Youth. The analyses statistically controlled for measured characteristics of the mothers and families and exposure to other prenatal psychoactive substances. In the primary analyses, siblings differentially exposed to prenatal alcohol were compared. Setting and participants Women were recruited from the community using a stratified and clustered probability sample and were followed longitudinally. The sample included 8621 offspring of 4912 mothers. Main outcome measures Maternal report of conduct problems (CPs) and attention/impulsivity problems (AIPs) during childhood (ages 4-11 years) using standardized assessments related to psychiatric diagnoses. Results There was an association between PAE and offspring CPs that was independent of confounded genetic and fixed environmental effects and the measured covariates. The CPs in children of mothers who drank daily during pregnancy were 0.35 SD greater than th…

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Metadata

Authors
D’Onofrio, B. M., Van Hulle, C. A., Waldman, I. D., Rodgers, J. L., Rathouz, P. J., & Lahey, B. B.
ORCID
Venue
Archives of General Psychiatry
Publisher
American Medical Association (AMA)
Published
2007-11-01
Volume
64
Issue
11
Pages
1296
ISSN
0003-990X (ISSN-L)
DOI
10.1001/archpsyc.64.11.1296
OpenAlex
W2148565287
Cited by
170
References
55
Citations by year
2026: 4 · 2025: 1 · 2024: 5 · 2023: 6 · 2022: 9 · 2021: 9 · 2020: 7 · 2019: 7 · 2018: 9 · 2017: 12 · 2016: 7 · 2015: 8 · 2014: 8 · 2013: 14 · 2012: 10
FWCI
13.95
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of General Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (R01MH070025)
Topics
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords
prenatal alcohol exposure, fetal alcohol spectrum disorders, child conduct problems, sibling comparison, causal inference, environmental mediation
MeSH terms
Adolescent, Adult, Alcohol Drinking, Attention Deficit Disorder with Hyperactivity, Child, Child, Preschool, Female, Health Surveys, Humans, Longitudinal Studies, Male, Pregnancy, Prenatal Exposure Delayed Effects, Risk Factors, United States, Conduct Disorder

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