The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
7.5% Sodium Chloride/Dextran for Resuscitation of Trauma Patients Undergoing Helicopter Transport
Abstract
To evaluate the use of hypertonic saline/dextran solutions in the prehospital resuscitation of severely injured patients, we administered 250 mL of either 7.5% sodium chloride/dextran 70 (HSD) (n = 83) or lactated Ringer's solution (n = 83), followed by conventional isotonic fluids, to 166 trauma patients with systolic blood pressures less than or equal to 100 mm Hg, in a prospective, randomized, double-blinded clinical trial. Patients in the sodium chloride/dextran 70 group required less fluid before hospitalization and arrived in the emergency department with higher systolic blood pressures than patients in the lactated Ringer's solution group. The rate of survival to hospital discharge for the entire cohort was 64% for patients in the sodium chloride/dextran 70 group vs 59% for patients in the lactated Ringer's solution group. The rate of survival to hospital discharge for the patients with severe head injuries was 32% for the sodium chloride/dextran 70 group vs 16% for the lactated Ringer's solution group. Actuarial survival for patients with severe head injuries in the sodium chloride/dextran 70 group compared with patients with severe head injuries in the lactated Ringer's solution group did not quite reach statistical significance. There were no adverse side effects associated with sodium chloride/dextran 70 administration. Administration of small volumes of sodium chloride/dextran 70 before hospitalization increased the blood pressure of severely injured patients more effectively than did lactated Ringer's solution and showed tendencies toward improving survival in the patients with severe head injuries.
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Cites
Statistical Methods for Rates and Proportions
Fleiss, J. L., Levin, B., & Paik, M. C. (2003) · Wiley Series in Probability and Statistics · doi:10.1002/0471445428 · Cited by 18,646
ABBREVIATED INJURY SCALE :(1985 REVISION. )
Gennarelli, T. A. (1985) · Cited by 447
Prehospital Stabilization of Critically Injured Patients
Smith, J. P., Bodai, B. I., HILL, A. S., & Frey, C. F. (1985) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-198501000-00011 · Cited by 279
A comparison of several hypertonic solutions for resuscitation of bled sheep
Smith, G. J., Kramer, G. C., Perron, P., Nakayama, S.-I., Gunther, R. A., & Holcroft, J. W. (1985) · Journal of Surgical Research · doi:10.1016/0022-4804(85)90120-9 · Cited by 234
Small-volume resuscitation with hypertonic saline dextran solution.
Kramer, G. C., Perron, P. R., Lindsey, D. C., Ho, H. S., Gunther, R. A., Boyle, W. A., & Holcroft, J. W. (1986) · PubMed · Cited by 231
3% NaCl and 7.5% NaCl/Dextran 70 in the Resuscitation of Severely Injured Patients
HOLCROFT, J. W., VASSAR, M. J., TURNER, J. E., DERLET, R. W., & KRAMER, G. C. (1987) · Annals of Surgery · doi:10.1097/00000658-198709000-00006 · Cited by 227
Self-citationThe Effect of Prehospital Fluids on Survival in Trauma Patients
KAWESKI, S. M., SISE, M. J., & VIRGILIO, R. W. (1990) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-199010000-00005 · Cited by 209
Analysis of Potential Risks Associated With 7.5% Sodium Chloride Resuscitation of Traumatic Shock
Vassar, M. J. (1990) · Archives of Surgery · doi:10.1001/archsurg.1990.01410220093013 · Cited by 180
Self-citationGross, D. R., Landau, E. H., Klin, B., et al. (1989) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-198901000-00016 · Cited by 115
Zornow, M. H., Scheller, M. S., & Shackford, S. R. (1989) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-198904000-00011 · Cited by 105
Cited by
Colloids versus crystalloids for fluid resuscitation in critically ill patients
Perel, P., Roberts, I., & Ker, K. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000567.pub6 · Cited by 1,115
Use of hypertonic saline solutions in treatment of cerebral edema and intracranial hypertension
Qureshi, A. I., & Suarez, J. I. (2000) · Critical Care Medicine · doi:10.1097/00003246-200009000-00032 · Cited by 366
The Phenomenon of “Fluid Creep” in Acute Burn Resuscitation
Saffle, J. R. (2007) · Journal of Burn Care & Research · doi:10.1097/bcr.0b013e318053d3a1 · Cited by 326
Colloids versus crystalloids for fluid resuscitation in critically ill people
Lewis, S. R., Pritchard, M. W., Evans, D. J., Butler, A. R., Alderson, P., Smith, A. F., & Roberts, I. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000567.pub7 · Cited by 315
Bulger, E. M., May, S., Kerby, J. D., Emerson, S., Stiell, I. G., Schreiber, M. A., Brasel, K. J., Tisherman, S. A., Coimbra, R., Rizoli, S., et al. (2011) · Annals of Surgery · doi:10.1097/sla.0b013e3181fcdb22 · Cited by 284
Metadata
- Authors
- Vassar, M. J.
- Venue
- Archives of Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 1991-09-01
- Volume
- 126
- Issue
- 9
- Pages
- 1065
- ISSN
- 0004-0010 (ISSN-L)
- OpenAlex
- W2023783219
- Cited by
- 276
- References
- 12
- FWCI
- 6.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: 7.5% Sodium Chloride/Dextran for Resuscitation of Trauma Patients Undergoing Helicopter Transport. https://app.cochat.ai/papers/10.1001/archsurg.1991.01410330019002
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- Vassar, M. J. (1991). 7.5% Sodium Chloride/Dextran for Resuscitation of Trauma Patients Undergoing Helicopter Transport. Archives of Surgery. https://doi.org/10.1001/archsurg.1991.01410330019002
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