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Cited by 114Breast Cancer Treatment StudiesEstrogen and related hormone effectsMenopause: Health Impacts and Treatments

The DOI matches its Crossref record.

Testosterone Propionate Therapy in Breast Cancer

I S GOLDENBERG·1964·JAMA
DOI 10.1001/jama.1964.03060380037009
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Abstract

A CONTINUING collaborative study of hormonal therapy of recurrent, primary inoperable and metastatic carcinoma of the female breast, sponsored by the Cancer Chemotherapy National Service Center of the National Cancer Institute, has been conducted since 1957 by a group of investigators at 23 institutions. New hormonal preparations have been administered to patient groups under protocol standards1in double-blind fashion in conjunction with known hormonal reference standards. This procedure allows for objective evaluation of the new compounds as well as established anticancer agents such as testosterone propionate. The present report details results of testosterone propionate therapy in 521 women beginning therapy between Jan 16, 1957, and Sept 24, 1960, under the group protocol and followed through Dec 31, 1963. Clinical Material and Methods Only women with advancing disease previously untreated with hormones are eligible for protocol therapy, and all patients must be naturally or artificially postmenopausal. A randomization scheme based on

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Crossref · 10.1001/jama.1964.03060380037009

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Metadata

Authors
GOLDENBERG, I. S.
Corresponding author
I S GOLDENBERG
Venue
JAMA
Publisher
American Medical Association (AMA)
Published
1964-06-22
Volume
188
Issue
12
Pages
1069
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
DOI
10.1001/jama.1964.03060380037009
OpenAlex
W2417813231
Cited by
114
References
0
Citations by year
2024: 3 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 1 · 2019: 5 · 2018: 3 · 2017: 4 · 2016: 8 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 5
FWCI
3.00
Type
journal article
Language
en
Open access
closed
Locations
  • JAMA (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Breast Cancer Treatment Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Keywords
testosterone propionate, breast cancer, hormone therapy, androgen therapy, metastatic breast cancer, inoperable breast cancer, postmenopausal women
MeSH terms
Breast Neoplasms, Castration, Female, Humans, Menopause, Neoplasms, Ovary, Prognosis, Testosterone, Biomedical Research, Testosterone Propionate

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