The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Suppression of Plasma Renin Activity in Primary Aldosteronism: Distinguishing Primary From Secondary Aldosteronism in Hypertensive Disease
Abstract
THE OCCURRENCE in a hypertensive patient of increased production of aldosterone, and of the hypokalemia which often accompanies it, is due either to (1) the presence of an aldosterone-secreting adrenocortical tumor (primary aldosteronism), or (2) the presence of a functional renal hemodynamic change which stimulates the renal juxtaglomerular cells to secrete into the blood abnormally large amounts of renin. In the latter case, an increased quantity of angiotensin II is thus generated. Angiotensin II has been established to be a potent stimulus for the secretion of aldosterone by the adrenal cortices of man.1,2Although increased secretion of aldosterone can be induced in man by other mechanisms, it is now clear that, when hypersecretion of aldosterone occurs in human renal hypertension (secondary aldosteronism), it is the result of increased activity of the renin-angiotensin system. This seems to be true whether the decreased "stretch"3at the renal baroreceptor site (the
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Citations
Cites
Double Isotope Derivative Assay of Aldosterone in Biological Extracts
Kliman, B., & Peterson, R. E. (1960) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76855-0 · Cited by 591
Clinical characteristics of primary aldosteronism from an analysis of 145 cases
Conn, J. W., Knopf, R. F., & Nesbit, R. M. (1964) · The American Journal of Surgery · doi:10.1016/0002-9610(64)90252-1 · Cited by 429
Self-citationNEW PROCEDURES FOR MEASUREMENT OF HUMAN PLASMA ANGIOTENSIN AND RENIN ACTIVITY LEVELS.
Boucher, R., Veyrat, R., de Champlain, J., & Genest, J. (1964) · PubMed Central · Cited by 401
ALDOSTERONE SECRETION AND PRIMARY AND MALIGNANT HYPERTENSION *
Laragh, J. H., Ulick, S., Januszewicz, V., Deming, Q. B., Kelly, W. G., & Lieberman, S. (1960) · Journal of Clinical Investigation · doi:10.1172/jci104124 · Cited by 305
Conn, J. W. (1964) · PubMed · Cited by 171
Self-citationVARIATIONS IN PLASMA RENIN CONCENTRATION IN SEVERAL PHYSIOLOGICAL AND PATHOLOGICAL STATES.
Brown, J. J., Davies, D. L., Lever, A. F., & Robertson, J. I. S. (1964) · PubMed Central · Cited by 170
Laragh, J. H. (1962) · Circulation · doi:10.1161/01.cir.25.1.203 · Cited by 124
Potassium-losing pyelonephritis and malignant hypertension: a case report with balance studies.
Eales, L., & Linder, G. C. (1959) · PubMed · Cited by 20
Cited by
17-Hydroxylation deficiency in man
Biglieri, E. G., Herron, M. A., & Brust, N. (1966) · Journal of Clinical Investigation · doi:10.1172/jci105499 · Cited by 561
Primary Aldosteronism: Diagnosis, Localization, and Treatment
WEINBERGER, M. H., GRIM, C. E., HOLLIFIELD, J. W., KEM, D. C., GANGULY, A., KRAMER, N. J., YUNE, H. Y., WELLMAN, H., & DONOHUE, J. P. (1979) · Annals of Internal Medicine · doi:10.7326/0003-4819-90-3-386 · Cited by 352
Prevalence of Primary Aldosteronism among Asian Hypertensive Patients in Singapore1
Loh, K.-C., Koay, E. S., Khaw, M.-C., Emmanuel, S. C., & Young, W. F. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6752 · Cited by 345
Adrenal adenoma and hypertension
Kokko, J. P., Brown, T., & Berman, M. (1967) · The Lancet · doi:10.1016/s0140-6736(67)91092-6 · Cited by 101
Dévényi, I. (1967) · Journal of Clinical Pathology · doi:10.1136/jcp.20.1.49 · Cited by 25
Metadata
- Authors
- Conn, J. W., Cohen, E. L., & Rovner, D. R.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 1964-10-19
- Volume
- 190
- Issue
- 3
- Pages
- 213-21
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2054248529
- Cited by
- 295
- References
- 8
- FWCI
- 37.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Conn, J. W., Cohen, E. L., & Rovner, D. R. (1964). Suppression of Plasma Renin Activity in Primary Aldosteronism: Distinguishing Primary From Secondary Aldosteronism in Hypertensive Disease. JAMA. https://doi.org/10.1001/jama.1964.03070160037008
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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