Candida Myocarditis Causing Complete Atrioventricular Block
Abstract
Complete heart block developed unexpectedly in a 54-year-old patient with acute myelomonocytic leukemia and was successfully treated with temporary transvenous pacing. Subsequent autopsy showed several microabscesses ofCandida albicansin the His bundle, without evidence of leukemic infiltration or hemorrhage into the conduction system. While the general incidence and importance ofCandidamyocarditis in leukemic patients is unknown, fungal myocarditis with abscess formation should be considered as a cause of cardiac rhythm disturbances in these and other immunosuppressed patients.
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Candidal myocarditis may cause complete atrioventricular block, necessitating placement of a pacemaker.
“candidal myocarditis may cause complete atrioventricular block, necessitating placement of a pacemaker [225].”
From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [225]
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Guidelines for Treatment of Candidiasis
Pappas, P. G., Rex, J. H., Sobel, J. D., Filler, S. G., Dismukes, W. E., Walsh, T. J., & Edwards, J. E. (2004) · Clinical Infectious Diseases · doi:10.1086/380796 · Cited by 1,440 · see citing works
Fungal infections of the heart: Analysis of 51 autopsy cases
Walsh, T. J., Hutchins, G. M., Bulkley, B. H., et al. (1980) · The American Journal of Cardiology · doi:10.1016/0002-9149(80)90659-1 · Cited by 103 · see citing works
Fungal Infections in the Compromised Host
Meunier, F. (1988) · Springer eBooks · doi:10.1007/978-1-4615-6642-7_8 · Cited by 49 · see citing works
Candida myocarditis without valvulitis
Franklin, W. G., Simon, A. B., & Sodeman, T. M. (1976) · The American Journal of Cardiology · doi:10.1016/0002-9149(76)90805-5 · Cited by 46 · see citing works
Gowden's disease.A cutaneous marker of breast cancer
Brownstein, M. H., Wolf, M., & Bikowski, J. (1978) · Cancer · doi:10.1002/1097-0142(197806)41:6 · Cited by 236 · see citing works
Aspergillus Vegetative Endocarditis and Complete Heart Block in a Patient with Acute Leukemia
Mikulski, S. M., Love, L. J., Bergquist, E. J., et al. (1979) · CHEST Journal · doi:10.1378/chest.76.4.473 · Cited by 17 · see citing works
Torres-Tirado, D., Knabb, M., Castaño, I., Patrón-Soberano, A., De Las Peñas, A., & Rubio, R. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00229.2014 · Cited by 10 · see citing works
Nosanchuk, J. D. (2002) · Frontiers in bioscience · doi:10.2741/nosan · Cited by 6 · see citing works
Heart Block in Leukemia and Lymphoma
JOHNSON, C. D. (1984) · Clinical Progress in Pacing and Electrophysiology · doi:10.1111/j.1540-8167.1984.tb01675.x · Cited by 1 · see citing works
Infectious diseases: fortieth and final annual review of significant publications
Reimann, H. A. (1975) · Postgraduate Medical Journal · doi:10.1136/pgmj.51.599.600 · Cited by 1 · see citing works
Liu, S., & Nosanchuk, J. D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-809633-8.21020-0 · Cited by 1 · see citing works
- Authors
- Van Kirk, J. E.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1974-02-25
- Volume
- 227
- Issue
- 8
- Pages
- 931
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2152671644
- Cited by
- 18
- References
- 0
- Citations by year
- 2024: 1 · 2020: 1 · 2019: 1 · 2015: 1
- FWCI
- 2.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Keywords
- Candida albicans, complete heart block, atrioventricular block, acute myelomonocytic leukemia, conduction system, temporary transvenous pacing, immunosuppression, cardiac arrhythmias
- MeSH terms
- Acute Disease, Autopsy, Candida albicans, Candidiasis, Electrocardiography, Heart Block, Heart Septum, Humans, Immunosuppressive Agents, Leukemia, Myeloid, Male, Middle Aged, Myocarditis, Pacemaker, Artificial
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