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Tuberculous Meningitis
Abstract
To evaluate modern treatment and identify important factors influencing the outcome of tuberculous meningitis, clinical and laboratory findings in 52 patients aged from 9 months to 68 years have been reviewed. Patients were classified by clinical criterions at admission and at the start of treatment. Delay in commencing treatment was associated with deterioration and consequently poorer prognosis, but some severely ill patients made a good recovery. Forty-four survivors (85%) recovered, and only two patients (4%) had severe residual disability; eight (15%) of the patients died. Treatment should commence as soon as possible on clinical grounds without necessarily waiting for demonstration ofMycobacterium tuberculosis, as the organism can often be demonstrated in CSF withdrawn after the start of drug therapy. (JAMA241:264-268, 1979)
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Cited by
Tuberculous meningitis: a uniform case definition for use in clinical research
Marais, S., Thwaites, G., Schoeman, J. F., Török, M. E., Misra, U. K., Prasad, K., Donald, P. R., Wilkinson, R. J., & Marais, B. J. (2010) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70138-9 · Cited by 932
Diagnosis and Treatment of Extrapulmonary Tuberculosis
Lee, J. Y. (2015) · Tuberculosis and Respiratory Diseases · doi:10.4046/trd.2015.78.2.47 · Cited by 512
Sharma, S. K., Mohan, A., & Kohli, M. (2021) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2021.1927718 · Cited by 441
Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features
Thwaites, G., Chau, T., Stepniewska, K., Phu, N., Chuong, L., Sinh, D., White, N., Parry, C., & Farrar, J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11318-3 · Cited by 395
Tuberculosis of the central nervous system
Garg, R. K. (1999) · Postgraduate Medical Journal · doi:10.1136/pgmj.75.881.133 · Cited by 306
Metadata
- Authors
- Kennedy, D. H.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1979-01-19
- Volume
- 241
- Issue
- 3
- Pages
- 264
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W4232853085
- Cited by
- 294
- References
- 0
- FWCI
- 6.50
- Type
- journal article
- Language
- en
- Open access
- closed
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