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Cited by 306

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Tuberculosis of the central nervous system

Open access
Garg, Ravindra Kumar·1999·Postgraduate Medical Journal

Abstract

Summary: Tuberculous involvement of the brain and spinal cord are common neurological disorders in developing countries and have recently shown a resurgence in developed ones. Tuberculous meningitis is an important manifestation and is associated with high morbidity and mortality. Diagnosis is based on clinical features, cerebrospinal fluid changes, and imaging characteristics. Bacteriological confirmation is not possible in all cases as serological tests do not have sufficient sensitivity and specificity. The polymerase chain reaction shows promise for the future. Appropriate chemotherapeutic agents should be administered as early as possible, although there is no unanimity concerning chemotherapeutic regimens or optimal duration of treatment. The patient's clinical stage at presentation is the most important prognostic factor. The role of corticosteroids is controversial but they should be administered to all patients presenting in stage III. Surgical procedures are directed at management of the hydrocephalus. Focal lesions, intracranial tuberculomas, and tuberculous abscesses, are usually located in cerebral or cerebellar hemispheres, uncommonly in brainstem and very rarely in spinal cord. They do not usually require surgical intervention and respond well to antituberculous treatment, along with corticosteroids.

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Metadata

Authors
Garg, R. K.
Venue
Postgraduate Medical Journal
Published
1999-03-01
Volume
75
Issue
881
Pages
133-140
ISSN
  • 0032-5473 (ISSN-L)
  • 1469-0756
OpenAlex
W2016353926
Cited by
306
References
28
FWCI
4.54
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Tuberculosis of the central nervous system. https://app.cochat.ai/papers/10.1136/pgmj.75.881.133
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Garg, R. K. (1999). Tuberculosis of the central nervous system. Postgraduate Medical Journal. https://doi.org/10.1136/pgmj.75.881.133

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.