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Cited by 254

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

A Case-Control Study of Menopausal Estrogen Therapy and Breast Cancer

Ross, Ronald K.·1980·JAMA: The Journal of the American Medical Association

Abstract

The association between estrogen replacement therapy and female breast cancer was studied in two Los Angeles area retirement communities. The 138 study cases of breast cancer occurring in residents younger than 75 years were compared with age- and race-matched community control subjects. The risk ratio for a total cumulative dose in excess of 1,500 mg was estimated to be 2.5 in women with intact ovaries. This increase was present using various independent sources of drug usage information but was inconsistent at low dose and undetectable in oophorectomized women. No important sources of confounding could be identified, and no risk modifiers could be identified except for a history of surgically confirmed benign breast disease. In such women with intact ovaries, the risk ratio for a high cumulative dose rose to 5.7 relative to nonusers with normal breasts.

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Crossref · 10.1001/jama.1980.03300420019018

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Metadata

Authors
Ross, R. K.
Venue
JAMA: The Journal of the American Medical Association
Published
1980-04-25
Volume
243
Issue
16
Pages
1635
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
OpenAlex
W2050266344
Cited by
254
References
1
FWCI
18.03
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Case-Control Study of Menopausal Estrogen Therapy and Breast Cancer. https://app.cochat.ai/papers/10.1001/jama.1980.03300420019018
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Ross, R. K. (1980). A Case-Control Study of Menopausal Estrogen Therapy and Breast Cancer. JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.1980.03300420019018

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.