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Lipid Research Clinics Program
Abstract
To the Editor.— The article by the Lipid Research Clinics Program1on reduction in instances of coronary artery disease was a very useful study for the physician interested in primary prevention of coronary artery disease. I have had relatively poor success keeping patients on a regimen of cholestyramine in my own practice because of the cost. The least expensive form of cholestyramine resin available through a local pharmacy would cost my patient $31.20 a week to take 24 g/day. This comes to a total cost of $1,622.40 a year. If, as the study suggests, there are 1 1/2 million Americans who would qualify for this form of therapy, the cost considerations become impressive. Some simple arithmetic demonstrates that the cost nationwide for each patient spared a cardiac end point is $715,764.70. Who says that coronary artery surgery is expensive?
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Citations
Cited by
Freeman, D. J., Norrie, J., Sattar, N., Neely, R. D. G., Cobbe, S. M., Ford, I., Isles, C., Lorimer, A. R., Macfarlane, P. W., McKillop, J. H., et al. (2001) · Circulation · doi:10.1161/01.cir.103.3.357 · Cited by 844
Incidence and precursors of hypertension in young adults: The Framingham offspring study
Garrison, R. J., Kannel, W. B., Stokes, J., & Castelli, W. P. (1987) · Preventive Medicine · doi:10.1016/0091-7435(87)90087-9 · Cited by 789
Familial Hypercholesterolemia: Screening, diagnosis and management of pediatric and adult patients
Goldberg, A. C., Hopkins, P. N., Toth, P. P., Ballantyne, C. M., Rader, D. J., Robinson, J. G., Daniels, S. R., Gidding, S. S., de Ferranti, S. D., Ito, M. K., et al. (2011) · Journal of clinical lipidology · doi:10.1016/j.jacl.2011.03.001 · Cited by 622
Jacobson, T. A., Ito, M. K., Maki, K. C., Orringer, C. E., Bays, H. E., Jones, P. H., McKenney, J. M., Grundy, S. M., Gill, E. A., Wild, R. A., et al. (2014) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2014.07.007 · Cited by 462
Cusi, K. (1996) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.81.11.4059 · Cited by 455
Metadata
- Authors
- Renfrew, R. A.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1984-11-09
- Volume
- 252
- Issue
- 18
- Pages
- 2545
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2012952446
- Cited by
- 829
- References
- 0
- FWCI
- 50.04
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Lipid Research Clinics Program. https://app.cochat.ai/papers/10.1001/jama.1984.03350180015009
- The paper
- Renfrew, R. A. (1984). Lipid Research Clinics Program. JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.1984.03350180015009
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
