Cited by 802Cardiac Health and Mental HealthAcute Myocardial Infarction ResearchCardiovascular and exercise physiology

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Cardiac Rehabilitation After Myocardial Infarction: Combined Experience of Randomized Clinical Trials

Oldridge, Neil B.·1988·JAMA

Abstract

Randomized clinical trials of cardiac rehabilitation following myocardial infarction have typically demonstrated a lower mortality in treated patients, but with a statistically significant reduction in only one trial. To overcome the problem of not being able to detect small but clinically important benefits in mortality in randomized clinical trials of exercise and risk factor rehabilitation after myocardial infarction with small numbers of patients, we carried out a meta-analysis on the combined results of ten randomized clinical trials that included 4347 patients (control, 2145 patients; rehabilitation, 2202 patients). The pooled odds ratios of 0.76 (95% confidence intervals, 0.63 to 0.92) for all-cause death and of 0.75 (95% confidence intervals, 0.62 to 0.93) for cardiovascular death were significantly lower in the rehabilitation group than in the control group, with no significant difference for nonfatal recurrent myocardial infarction. These results suggest that, for appropriately selected patients, comprehensive cardiac rehabilitation has a beneficial effect on mortality but not on nonfatal recurrent myocardial infarction. (JAMA1988;260:945-950)

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Crossref · 10.1001/jama.1988.03410070073031

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Metadata

Authors
Oldridge, N. B.
Corresponding author
Oldridge, Neil B.
Venue
JAMA
Published
1988-08-19
Volume
260
Issue
7
Pages
945
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
OpenAlex
W4322695695
Cited by
800
References
0
Citations by year
2026: 2 · 2025: 10 · 2024: 8 · 2023: 10 · 2022: 11 · 2021: 12 · 2020: 17 · 2019: 16 · 2018: 16 · 2017: 18 · 2016: 25 · 2015: 28 · 2014: 25 · 2013: 26 · 2012: 12
FWCI
8.98
Type
journal article
Language
en
Open access
closed
Locations
JAMA (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Keywords
cardiac rehabilitation, myocardial infarction, all-cause mortality, cardiovascular mortality, reinfarction, exercise therapy

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