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Cited by 421

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

The Association Between Genital Ulcer Disease and Acquisition of HIV Infection in Homosexual Men

Stamm, Walter E.·1988·JAMA: The Journal of the American Medical Association
DOI 10.1001/jama.1988.03410100119036
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Abstract

We analyzed the association of herpes simplex virus (HSV) infection and syphilis, the two most common causes of genital ulceration in homosexual men, with human immunodeficiency virus (HIV) infection in 200 men enrolled between 1983 and 1986 into a study evaluating the microbial causes of acute proctitis. Infection with HIV was independently associated with a history of syphilis, serologic evidence of syphilis, a history of HSV infection, and antibody to HSV-2. Antibody to HIV was not associated with a history of other genital infections or with antibody to Chlamydia trachomatis or HSV-1. Similar associations were observed in 111 asymptomatic homosexuals seen for HIV screening. Men who presented with primary HSV proctitis had a lower prevalence of HIV antibody than those with preexisting HSV-2 antibody (44% vs 68%); this suggests that HSV-2 infection antedated HIV infection. These data suggest that genital ulcerative diseases are an important risk factor for the acquisition of HIV infection in homosexual men; measures directed at control of these diseases may reduce the transmission of HIV in this population.

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Metadata

Authors
Stamm, W. E.
Venue
JAMA: The Journal of the American Medical Association
Publisher
American Medical Association (AMA)
Published
1988-09-09
Volume
260
Issue
10
Pages
1429
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
DOI
10.1001/jama.1988.03410100119036
OpenAlex
W1988917007
Cited by
421
References
17
FWCI
21.22
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Association Between Genital Ulcer Disease and Acquisition of HIV Infection in Homosexual Men. https://app.cochat.ai/papers/10.1001/jama.1988.03410100119036
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Stamm, W. E. (1988). The Association Between Genital Ulcer Disease and Acquisition of HIV Infection in Homosexual Men. JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.1988.03410100119036

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.