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Cited by 491

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Overview of Results of Randomized Clinical Trials in Heart Disease: I. Treatments Following Myocardial Infarction

Yusuf, Salim·1988·JAMA

Abstract

WHEN Daniel1requested that he and his compatriots be served pulse and water while Nebuchadnezzar's other young servants be served the king's food and wine, he was inaugurating the first recorded clinical trial. Today we would criticize Daniel's attempt to demonstrate the superiority of his simple diet. He failed to assign the two diets at random; neither the experimental subjects nor the eunuchs who were to measure the ten-day outcome, fairness of countenance, were blinded to the treatment; and the sample size, four subjects on the experimental diet and a larger unspecified number on kingly fare, was too small to be likely to detect a difference in outcome. Despite, or perhaps because of, the faulty design, the results supported Daniel's hypothesis. "And at the end of ten days their countenances appeared fairer, and they were fatter in flesh, than all the youths that did eat of the king's food."

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Crossref · 10.1001/jama.1988.03410140100032

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Metadata

Authors
Yusuf, S.
Venue
JAMA
Published
1988-10-14
Volume
260
Issue
14
Pages
2088
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
OpenAlex
W2069256497
Cited by
491
References
2
FWCI
29.37
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Overview of Results of Randomized Clinical Trials in Heart Disease: I. Treatments Following Myocardial Infarction. https://app.cochat.ai/papers/10.1001/jama.1988.03410140100032
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Yusuf, S. (1988). Overview of Results of Randomized Clinical Trials in Heart Disease: I. Treatments Following Myocardial Infarction. JAMA. https://doi.org/10.1001/jama.1988.03410140100032

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.