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Designing Clinical Research: An Epidemiologic Approach
Abstract
"Why this sample size?" "But those aren't parametric data." "That's not an appropriate control group!" So it goes when editors meet to decide which studies to publish and which not. There is lots of wondering aloud, mixed with colorful editorial epithets, about why investigators conceived, carried out, and reported their project this way rather than that. These deliberations turn on two points: Is the work valid and will the reader gain from having seen it? Such questions imply, rightly so I think, that the reporting of research is a collaborative effort between those who do it and those who read it. Only in the last decade has this been fully realized by the clinical epidemiologists who are in a position to do something about it. Many books, great and small (not a few of which have been reviewed in these pages), have appeared in an attempt to explain how valid
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Citations
Cited by
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Tabor, H. K., Risch, N. J., & Myers, R. M. (2002) · Nature Reviews Genetics · doi:10.1038/nrg796 · Cited by 1,076
Cohort studies: marching towards outcomes
Grimes, D. A., & Schulz, K. F. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07500-1 · Cited by 494
Challenges in recruitment of research participants
Patel, M. X., Doku, V., & Tennakoon, L. (2003) · Advances in Psychiatric Treatment · doi:10.1192/apt.9.3.229 · Cited by 465
Measuring errors and adverse events in health care
Thomas, E. J., & Petersen, L. A. (2003) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2003.20147.x · Cited by 455
Weaver, E. M., Woodson, B. T., & Steward, D. L. (2005) · Otolaryngology–Head and Neck Surgery · doi:10.1016/j.otohns.2004.11.001 · Cited by 159
Metadata
- Authors
- Riesenberg, D.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1989-09-15
- Volume
- 262
- Issue
- 11
- Pages
- 1532
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W1988538312
- Cited by
- 415
- References
- 0
- FWCI
- 2.30
- Type
- journal article
- Language
- en
- Open access
- closed
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How to cite
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- CoChat. (2026). Citation check: Designing Clinical Research: An Epidemiologic Approach. https://app.cochat.ai/papers/10.1001/jama.1989.03430110130046
- The paper
- Riesenberg, D. (1989). Designing Clinical Research: An Epidemiologic Approach. JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.1989.03430110130046
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
