Cited by 515Opioid Use Disorder TreatmentPain Management and Opioid UseSubstance Abuse Treatment and Outcomes

The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.

Association of Mental Health Disorders With Prescription Opioids and High-Risk Opioid Use in US Veterans of Iraq and Afghanistan

Seal, Karen H., Shi, Ying, Cohen, Gregory, Cohen, Beth E., Maguen, Shira, Krebs, Erin E., Neylan, Thomas C.·2012·JAMA

DOI 10.1001/jama.2012.234

Open this paper in CoChat — free account

Abstract

CONTEXT: Record numbers of Iraq and Afghanistan veterans survive their war injuries and yet continue to experience pain and mental health problems, particularly posttraumatic stress disorder (PTSD). Little is known about the association of mental health disorders and prescription opioid use. OBJECTIVE: To investigate the effect of mental health disorders, particularly PTSD, on risks and adverse clinical outcomes associated with prescription opioid use. DESIGN: Retrospective cohort study involving 141,029 Iraq and Afghanistan veterans who received at least 1 non-cancer-related pain diagnosis within 1 year of entering the Department of Veterans Affairs (VA) health care system from October 1, 2005, through December 31, 2010. MAIN OUTCOME MEASURES: Independent association of mental health disorders and the prescription of opioids, higher risk opioid use, and adverse clinical outcomes (eg, accidents and overdose) within 1 year of receiving a pain-related diagnosis. RESULTS: A total of 15,676 veterans were prescribed opioids within 1 year of their initial pain diagnosis. Compared with 6.5% of veterans without mental health disorders, 17.8% (adjusted relative risk [RR], 2.58; 95% CI, 2.49-2.67) of veterans with PTSD and 11.7% (adjusted RR, 1.74; 95% CI, 1.67-1.82) with other mental health diagnoses but without PTSD were significantly more likely to receive opioids for pain diagnoses. Of those who were prescribed pain medication, veterans with PTSD were more likely than those without mental health disorders to receive higher-dose opioids (22.7% vs 15.9%, adjusted RR, 1.42; 95% CI, 1.31-1.54), receive 2 or more opioids concurrently (19.8% vs 10.7%, adjusted RR, 1.87; 95% CI, 1.70-2.06), receive sedative hypnotics concurrently (40.7% vs 7.6%, adjusted RR, 5.46; 95% CI, 4.91-6.07), or obtain early opioid refills (33.8% vs 20.4%; adjusted RR, 1.64; 95% CI, 1.53-1.75). Receiving prescription opioids (vs not) was associated with an increased risk of adverse clinical outcomes for all veterans (9.5% vs 4.1%; RR, 2.33; 95% CI, 2.20-2.46), which was most pronounced in veterans with PTSD. CONCLUSION: Among US veterans of Iraq and Afghanistan, mental health diagnoses, especially PTSD, were associated with an increased risk of receiving opioids for pain, high-risk opioid use, and adverse clinical outcomes.

Integrity signals

Registry

Crossref · 10.1001/jama.2012.234

Cites

49 of 49 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391
Combat Duty in Iraq and Afghanistan, Mental Health Problems, and Barriers to Care
Hoge, C. W., Castro, C. A., Messer, S. C., McGurk, D., Cotting, D. I., & Koffman, R. L. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040603 · Cited by 4,778
Longitudinal Assessment of Mental Health Problems Among Active and Reserve Component Soldiers Returning From the Iraq War
Milliken, C. S., Auchterlonie, J. L., & Hoge, C. W. (2007) · JAMA · doi:10.1001/jama.298.18.2141 · Cited by 1,640
Opioid Prescriptions for Chronic Pain and Overdose
Dunn, K. M., Saunders, K. W., Rutter, C. M., Banta‐Green, C. J., Merrill, J. O., Sullivan, M. D., Weisner, C. M., Silverberg, M. J., Campbell, C. I., Psaty, B. M., et al. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-152-2-201001190-00006 · Cited by 1,265
Opioids in chronic non-cancer pain: systematic review of efficacy and safety
Kalso, E., Edwards, J. E., Moore, A. R., & McQuay, H. J. (2004) · Pain · doi:10.1016/j.pain.2004.09.019 · Cited by 1,216
Untitled work
Seal (2007) · doi:10.1001/archinte.167.5.476 · Cited by 936
Self-citation
Opioids for chronic noncancer pain: A meta-analysis of effectiveness and side effects
Furlan, A. D. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.051528 · Cited by 873
Trends and Risk Factors for Mental Health Diagnoses Among Iraq and Afghanistan Veterans Using Department of Veterans Affairs Health Care, 2002–2008
Seal, K. H., Metzler, T. J., Gima, K. S., Bertenthal, D., Maguen, S., & Marmar, C. R. (2009) · American Journal of Public Health · doi:10.2105/ajph.2008.150284 · Cited by 859
Self-citation
A Flood of Opioids, a Rising Tide of Deaths
Okie, S. (2010) · New England Journal of Medicine · doi:10.1056/nejmp1011512 · Cited by 832

Flagged first, then by citations

Show all 49 references

Sorted by citations

Items 201–300 of 514

Vintage treatments for PTSD: A reconsideration of tricyclic drugs
Davidson, J. R. T. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881114565143 · Cited by 20
Trends in comorbid opioid and stimulant use disorders among Veterans receiving care from the Veterans Health Administration, 2005–2019
Warfield, S. C., Bharat, C., Bossarte, R. M., DePhilippis, D., Farrell, M., Hoover, M., Larney, S., Marshalek, P. J., McKetin, R., & Degenhardt, L. J. (2022) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2022.109310 · Cited by 20
Opioid and Alcohol Misuse in Veterans with Chronic Pain: A Risk Screening Study
Vowles, K. E., Schmidt, Z., & Ford, C. G. (2022) · Journal of Pain · doi:10.1016/j.jpain.2022.06.003 · Cited by 20
Factors Associated with Opioid Initiation in OEF/OIF/OND Veterans with Traumatic Brain Injury
Hudson, T. J., Painter, J. T., Gressler, L. E., Lu, L., Williams, J., Booth, B. M., Martin, B. C., Sullivan, M. D., & Edlund, M. J. (2017) · Pain Medicine · doi:10.1093/pm/pnx208 · Cited by 20
Opioid-Induced Hypogonadism in the United States
Baillargeon, J., Raji, M. A., Urban, R. J., López, D. S., Williams, S. B., Westra, J. R., & Kuo, Y. (2019) · Mayo Clinic Proceedings Innovations Quality & Outcomes · doi:10.1016/j.mayocpiqo.2019.06.007 · Cited by 20
Barriers to Utilization of Prescription Drug Monitoring Programs Among Prescribing Physicians and Advanced Practice Registered Nurses at Veterans Health Administration Facilities in Oregon
Mastarone, G. L., Wyse, J. J. B., Wilbur, E. R., Morasco, B. J., Saha, S., & Carlson, K. F. (2019) · Pain Medicine · doi:10.1093/pm/pnz289 · Cited by 20
Opioid Pain Medication Prescription for Chronic Pain in Primary Care Centers: The Roles of Pain Acceptance, Pain Intensity, Depressive Symptoms, Pain Catastrophizing, Sex, and Age
Ramírez‐Maestre, C., Reyes-Pérez, Á., Esteve, R., López-Martínez, A. E., Bernardes, S. F., & Jensen, M. P. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17176428 · Cited by 20
Harmonizing Post-Market Surveillance of Prescription Drug Misuse: A Systematic Review of Observational Studies Using Routinely Collected Data (2000–2013)
Blanch, B., Buckley, N. A., Mellish, L., Dawson, A. H., Haber, P., & Pearson, S. (2015) · Drug Safety · doi:10.1007/s40264-015-0294-8 · Cited by 20
Risk of Overdose Associated With Co-prescription of Antipsychotics and Opioids: A Population-Based Cohort Study.
Szmulewicz, A., Bateman, B., Levin, R., & Huybrechts, K. (2021) · Schizophrenia bulletin · doi:10.1093/schbul/sbab116 · Cited by 13
Long-acting intramuscular naltrexone for opioid use disorder: Utilization and association with multi-morbidity nationally in the Veterans Health Administration
Kelly, M. M., Reilly, E. D., Quiñones, T., Desai, N., & Rosenheck, R. A. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.10.017 · Cited by 20
Comparison of Downstream Health Care Utilization, Costs, and Long‐Term Opioid Use: Physical Therapist Management Versus Opioid Therapy Management After Arthroscopic Hip Surgery
Rhon, D., Snodgrass, S., Cleland, J., Greenlee, T. A., Sissel, C. D., & Cook, C. (2018) · Physical Therapy · doi:10.1093/ptj/pzy019 · Cited by 18
Differences in opioid prescribing in low back pain patients with and without depression: a cross-sectional study of a national sample from the United States
Smith, J. A. V. D. L., Fuino, R. L., Pesis-Katz, I., Cai, X., Powers, B. A., Frazer, M. E., & Markman, J. D. (2017) · PAIN Reports · doi:10.1097/pr9.0000000000000606 · Cited by 19
Doctor hopping and doctor shopping for prescription opioids associated with increased odds of high‐risk use
Young, S. G., Hayes, C. J., Aram, J., & Tait, M. A. (2019) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.4838 · Cited by 19
Veterans' Health and Opioid Safety-Contexts, Risks, and Outreach Implications.
Bennett, A. S., Elliott, L. C., & Golub, A. L. (2015) · Europe PMC (PubMed Central) · Cited by 19
Buprenorphine: prospective novel therapy for depression and PTSD
Madison, C. A., & Eitan, S. (2020) · Psychological Medicine · doi:10.1017/s0033291720000525 · Cited by 21
PTSD risk associated with a functional DRD2 polymorphism in heroin‐dependent cases and controls is limited to amphetamine‐dependent individuals
Nelson, E. C., Heath, A. C., Lynskey, M. T., Arpana Agrawal, A., Henders, A. K., Bowdler, L. M., Todorov, A. A., Madden, P. A. F., Moore, E., Degenhardt, L. J., et al. (2013) · Addiction Biology · doi:10.1111/adb.12062 · Cited by 18
Posttraumatic stress disorder and somatic complaints: Contrasting Vietnam and OIF/OEF Veterans' experiences
Bourn, L. E., Sexton, M. B., Raggio, G. A., Porter, K. E., & Rauch, S. A. M. (2016) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2016.01.009 · Cited by 18
Group Visits for Overdose Education and Naloxone Distribution in Primary Care: A Pilot Quality Improvement Initiative
Spelman, J. F., Peglow, S. L., Schwartz, A. R., Burgo, L., McNamara, K., & Becker, W. C. (2017) · Pain Medicine · doi:10.1093/pm/pnx243 · Cited by 18
Insomnia Symptoms Among Female Veterans: Prevalence, Risk Factors, and the Impact on Psychosocial Functioning and Health Care Utilization
Babson, K. A., Wong, A. C., Morabito, D. M., & Kimerling, R. E. (2018) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.7154 · Cited by 18
Opioid-dependent regulation of high and low fear responses in two inbred mouse strains
Szklarczyk, K., Korostyński, M., Cieślak, P. E., Wawrzczak‐Bargieła, A., & Przewłocki, R. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.06.001 · Cited by 18
Correlates of prescription opioid therapy in Veterans with chronic pain and history of substance use disorder
Lovejoy, T. I., Dobscha, S. K., Turk, D. C., Weimer, M. B., & Morasco, B. J. (2016) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2014.10.0230 · Cited by 18
Treatment of Low Back Pain With Opioids and Nonpharmacologic Treatment Modalities for Army Veterans
Vanneman, M. E., Larson, M. J., Chen, C., Adams, R. S., Williams, T. V., Meerwijk, E. L., & Harris, A. H. S. (2018) · Medical Care · doi:10.1097/mlr.0000000000000977 · Cited by 18
Prevalence and Expenses of Outpatient Opioid Prescriptions, With Associated Sociodemographic, Economic, and Work Characteristics
Asfaw, A., Alterman, T., & Quay, B. (2019) · International Journal of Health Services · doi:10.1177/0020731419881336 · Cited by 18
Predicting opioid use disorder before and after the opioid prescribing peak in the United States: A machine learning tool using electronic healthcare records
Banks, T., Nguyen, T., Uhlmann, J. K., Nair, S. S., & Scherrer, J. F. (2023) · Health Informatics Journal · doi:10.1177/14604582231168826 · Cited by 17
What Are We Treating with Chronic Opioid Therapy?
Krashin, D. L., Sullivan, M. D., & Ballantyne, J. C. (2013) · Current Rheumatology Reports · doi:10.1007/s11926-012-0311-1 · Cited by 18
Prescription Drug Monitoring Program Inquiry in Psychiatric Assessment
Hackman, D. T., Greene, M., Fernandes, T. J., Brown, A. M., Wright, E. R., & Chambers, R. A. (2014) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.14m09020 · Cited by 17
A behavioral typology of opioid overdose risk behaviors among recent veterans in New York City
Bennett, A. S., Golub, A. L., & Elliott, L. C. (2017) · PLoS ONE · doi:10.1371/journal.pone.0179054 · Cited by 17
Prescription opioid misuse among heterosexual versus lesbian, gay, and bisexual military veterans: Evidence from the 2015-2017 national survey of drug use and health
Anderson‐Carpenter, K. D., Rutledge, J., & Mitchell, K. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.107794 · Cited by 18
Primary Care and Mental Health Prescribers, Key Clinical Leaders, and Clinical Pharmacist Specialists’ Perspectives on Opioids and Benzodiazepines
Hawkins, E. J., Lott, A. M. K., Danner, A. N., Malte, C. A., Hagedorn, H., Berger, D. B., Donovan, L. M., Sayre, G. G., Mariano, A. J., & Saxon, A. J. (2020) · Pain Medicine · doi:10.1093/pm/pnaa435 · Cited by 17
Lower Urinary Tract Dysfunction in Male Iraq and Afghanistan War Veterans: Association With Mental Health Disorders: A Population-based Cohort Study
Breyer, B. N., Cohen, B. E., Bertenthal, D., Rosen, R. C., Neylan, T. C., & Seal, K. H. (2013) · Urology · doi:10.1016/j.urology.2013.08.047 · Cited by 17
Self-citation
Novel Pharmacological Targets of Post-Traumatic Stress Disorders
Marazziti, D., Carmassi, C., Cappellato, G., Chiarantini, I., Massoni, L., Mucci, F., Arone, A., Violi, M., Palermo, S., Iorio, G. D., et al. (2023) · Life · doi:10.3390/life13081731 · Cited by 18
The Effect of Substance Use Disorders on the Association Between Guideline-concordant Long-term Opioid Therapy and All-cause Mortality
Gaither, J. R., Goulet, J. L., Becker, W. C., Crystal, S., Edelman, E. J., Gordon, K. S., Kerns, R. D., Rimland, D., Skanderson, M., Justice, A. C., et al. (2016) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000000255 · Cited by 16
Long-term prescription opioid use among US military service members injured in combat
Dalton, M. K., Manful, A., Jarman, M. P., Pisano, A. J., Learn, P. A., Koehlmoos, T. P., Weissman, J. S., Cooper, Z. R., & Schoenfeld, A. J. (2021) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000003133 · Cited by 16
Benefits and Challenges of Having a Service Dog Among Veterans in Recovery from Substance Use Harms
Dell, C. A., Kosteniuk, B., & Bentley, E. (2022) · Anthrozoös · doi:10.1080/08927936.2022.2074190 · Cited by 16
Opiate-Related Dependence/Abuse and PTSD Exposure Among the Active-Component U.S. Military, 2001 to 2008
Dabbs, C., Watkins, E. Y., Fink, D. S., Eick-Cost, A. A., & Millikan, A. M. (2014) · Military Medicine · doi:10.7205/milmed-d-14-00012 · Cited by 16
Fibromyalgia syndrome care of Iraq- and Afghanistan-deployed Veterans in Veterans Health Administration
Mohanty, A. F., Helmer, D. A., Muthukutty, A., McAndrew, L. M., Carter, M. E., Judd, J., Garvin, J. H., RHIA, CPHQ, CCS, et al. (2016) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2014.10.0265 · Cited by 16
Implementation and Evaluation of An Opioid Overdose Education and Naloxone Distribution (Oend) Program at A Veterans Affairs Medical Center
Pauly, J. B., Vartan, C. M., & Brooks, A. T. (2018) · Substance Abuse · doi:10.1080/08897077.2018.1449174 · Cited by 19
An Electronic Intervention to Improve Safety for Pain Patients Co-Prescribed Chronic Opioids and Benzodiazepines
Zaman, T., Rife, T., Batki, S. L., & Pennington, D. (2018) · Substance Abuse · doi:10.1080/08897077.2018.1455163 · Cited by 15
Iraq and Afghanistan Veterans: National Findings from VA Residential Treatment Programs
Cook, J. M., Dinnen, S., O'Donnell, C., Bernardy, N. C., Rosenheck, R. A., & Hoff, R. A. (2013) · Psychiatry · doi:10.1521/psyc.2013.76.1.18 · Cited by 15
A Facility-Wide Plan to Increase Access to Medication for Opioid Use Disorder in Primary Care and General Mental Health Settings
Spelman, J. F. (2021) · Federal Practitioner · doi:10.12788/fp.0186 · Cited by 15
The influence of propoxyphene withdrawal on opioid use in veterans
Hayes, C. J., Hudson, T. J., Phillips, M. M., Bursac, Z., Williams, J. S., Austin, M. A., Edlund, M. J., & Martin, B. C. (2015) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.3851 · Cited by 15
Explaining Prescription Opioid Misuse Among Veterans: A Theory-Based Analysis Using Structural Equation Modeling
Rigg, K. K., & DeCamp, W. (2014) · Military Behavioral Health · doi:10.1080/21635781.2014.917011 · Cited by 15
Opioid dispensing and overlap in veterans with non-cancer pain eligible for Medicare Part D
Suda, K. J., Smith, B., Bailey, L., Gellad, W. F., Huo, Z., Burk, M. L., Cunningham, F. E., & Stroupe, K. T. (2017) · Journal of the American Pharmacists Association · doi:10.1016/j.japh.2017.02.018 · Cited by 14
Preventing Opioid Overdose in the Clinic and Hospital
Peglow, S. L., & Binswanger, I. A. (2018) · Medical Clinics of North America · doi:10.1016/j.mcna.2018.02.005 · Cited by 14
Optimizing pain treatment interventions (OPTI): A pilot randomized controlled trial of collaborative care to improve chronic pain management and opioid safety—Rationale, methods, and lessons learned
Seal, K. H., Borsari, B. E., Tighe, J., Cohen, B. E., Delucchi, K., Morasco, B. J., Li, Y., Sachs, E., Abadjian, L. R., Watson, E. C., et al. (2018) · Contemporary Clinical Trials · doi:10.1016/j.cct.2018.12.006 · Cited by 15
Self-citation
Posttraumatic stress disorder, suicide, and unintended overdose death in later life: A national cohort study of veterans aged 50 and older
Clark, R., Kuffel, R. L., Neylan, T. C., Maguen, S., Li, Y., Boscardin, W. J., & Byers, A. L. (2022) · Journal of the American Geriatrics Society · doi:10.1111/jgs.18199 · Cited by 17
Self-citation
Predictors of Urine Drug Testing for Patients with Chronic Pain: Results from A National Cohort of U.S. Veterans
Morasco, B. J., Peters, D., Krebs, E. E., Kovas, A. E., Hart, K., & Dobscha, S. K. (2015) · Substance Abuse · doi:10.1080/08897077.2015.1110742 · Cited by 14
Self-citation
Protective Effects of Psychological Strengths Against Psychiatric Disorders Among Soldiers
Shrestha, A., Cornum, B. R., Vie, L. L., Scheier, L. M., Lester, M. P. B., & Seligman, M. E. P. (2018) · Military Medicine · doi:10.1093/milmed/usx189 · Cited by 14
Brief Counseling for Veterans with Musculoskeletal Disorder, Risky Substance Use, and Service Connection Claims
Rosen, M. I., Becker, W. C., Black, A. C., Martino, S., Edens, E. L., & Kerns, R. D. (2018) · Pain Medicine · doi:10.1093/pm/pny071 · Cited by 15
National Institute on Drug Abuse genomics consortium white paper: Coordinating efforts between human and animal addiction studies
Cates, H. M., Benca‐Bachman, C. E., de Guglielmo, G., Schoenrock, S. A., Shu, C., & Kallupi, M. (2019) · Genes Brain & Behavior · doi:10.1111/gbb.12577 · Cited by 14
Multispecialty Opioid Risk Reduction Program Targeting Chronic Pain and Addiction Management in Veterans.
Vaughn, I. A., Beyth, R. J., Ayers, M. L., Thornton, J. E., Tandon, R., Gingrich, T., & Mudra, S. A. (2019) · PubMed Central · Cited by 14
Potentially inappropriate benzodiazepine use in Australian adults: A population‐based study (2014–2017)
Zheng, D., Brett, J., Daniels, B. J., Buckley, N. A., Pearson, S., & Schaffer, A. L. (2020) · Drug and Alcohol Review · doi:10.1111/dar.13086 · Cited by 13
Heightened healthcare utilization & risk of mental disorders among Veterans with comorbid opioid use disorder & posttraumatic stress disorder
Mahoney, C. T., Moshier, S. J., Keane, T. M., & Marx, B. P. (2020) · Addictive Behaviors · doi:10.1016/j.addbeh.2020.106572 · Cited by 16
Trajectories of Opioid Coverage After Long-Term Opioid Therapy Initiation Among a National Cohort of US Veterans
Hayes, C. J., Gressler, L. E., Hu, B., Jones, B. L., Williams, J., & Martin, B. C. (2021) · Journal of Pain Research · doi:10.2147/jpr.s308196 · Cited by 13
Five-year Pain Intensity and Treatment Trajectories of Post-9/11 Veterans With Mild Traumatic Brain Injury
Song, K., Wang, C., McGeary, D. D., Jaramillo, C. A., Eapen, B. C., Amuan, M. E., McGeary, C. A., Potter, J. S., & Pugh, M. J. (2020) · Journal of Pain · doi:10.1016/j.jpain.2019.12.009 · Cited by 13
Post-traumatic stress disorder and risk of prescription opioid use, over-use, and misuse among World Trade Center Health Registry enrollees, 2015–2016
Takemoto, E. E., Brackbill, R. M., Martins, S. S., Farfel, M. R., & Jacobson, M. H. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.107959 · Cited by 14
Empower Veterans Program (EVP): a chronic pain management program demonstrates positive outcomes among veterans
Haun, J. N., Fowler, C. A., Venkatachalam, H. H., Saenger, M. S., Alman, A. C., Smith, B. M., Schneider, T., Benzinger, R., Stroupe, K., & French, D. D. (2023) · BMC Health Services Research · doi:10.1186/s12913-023-09327-5 · Cited by 12
Pain research using Veterans Health Administration electronic and administrative data sources
Abel, E. A., Brandt, C., Czlapinski, R. A., & Goulet, J. L. (2016) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2014.10.0246 · Cited by 14
Dual Use of Department of Veterans Affairs and Medicare Benefits on High‐Risk Opioid Prescriptions in Veterans Aged 65 Years and Older: Insights from the VA Musculoskeletal Disorders Cohort
Chui, P., Bastian, L. A., DeRycke, E. C., Brandt, C., Becker, W. C., & Goulet, J. L. (2018) · Health Services Research · doi:10.1111/1475-6773.13060 · Cited by 12
Effects of Pain and Prescription Opioid Use on Outcomes in a Collaborative Care Intervention for Anxiety
Roy‐Byrne, P., Sullivan, M. D., Sherbourne, C. D., Golinelli, D., Craske, M. G., Sullivan, G., & Stein, M. B. (2013) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e318278d475 · Cited by 12
Predictors of Positive Illicit Drug Tests After OEF/OIF Deployment Among Army Enlisted Service Members
Larson, M. J., Mohr, B. A., Jeffery, D. D., Adams, R. S., & Williams, T. V. (2016) · Military Medicine · doi:10.7205/milmed-d-15-00110 · Cited by 12
Benign monomelic amyotrophy in a 7-year-old girl with proximal upper limb involvement: case report
Yılmaz, O., Alemdaroğlu, İ., Karaduman, A. A., Haliloğlu, G., & Topaloğlu, H. (2011) · The Turkish Journal of Pediatrics · doi:10.24953/turkjpediatr.2011.1805 · Cited by 12
Repeated Exposure to Experimental Pain Differentiates Combat Traumatic Brain Injury with and without Post-Traumatic Stress Disorder
Strigo, I. A., Spadoni, A. D., Inslicht, S. S., & Simmons, A. N. (2017) · Journal of Neurotrauma · doi:10.1089/neu.2017.5061 · Cited by 12
Improving Nursing Confidence and Consistency in Assessment of Opioid Withdrawal: Efficacy of Simulation and Debriefing
Corrigan, D., Mix, R. L., Palmer, G. A., & Olson, S. A. (2018) · Journal of Psychosocial Nursing and Mental Health Services · doi:10.3928/02793695-20180503-05 · Cited by 12
Chronic Opioid Use after Laryngeal Cancer Treatment: A VA Study
Starr, N. C., Gal, T. J., Wells, L., Schadler, A. D., Pruden, S. J., & Aouad, R. K. (2020) · Otolaryngology · doi:10.1177/0194599820904693 · Cited by 12
Perceptions and Use of Alcohol and Medical Cannabis among Canadian Military Veterans Living with PTSD
Gibson, M., Williamson, L. E., Henwood, G., Chalmers, D., & Dell, C. A. (2021) · Journal of Veterans Studies · doi:10.21061/jvs.v7i1.200 · Cited by 12
The Addiction Psychiatrist as Dual Diagnosis Physician: A Profession in Great Need and Greatly Needed
Chambers, R. A. (2013) · Journal of Dual Diagnosis · doi:10.1080/15504263.2013.807072 · Cited by 12
Gender and the Association between Long-Term Prescription Opioid Use and New-Onset Depression
Salas, J., Scherrer, J. F., Ahmedani, B. K., Copeland, L. A., Bucholz, K. K., Sullivan, M. D., Burroughs, T. E., Schneider, D., & Lustman, P. J. (2017) · Journal of Pain · doi:10.1016/j.jpain.2017.09.004 · Cited by 13
Comparative Study of Opioid Initiation With Tramadol, Short-acting Hydrocodone, or Short-acting Oxycodone on Opioid-related Adverse Outcomes Among Chronic Noncancer Pain Patients
Acharya, M., Hayes, C. J., Li, C., Painter, J. T., Dayer, L. E., & Martin, B. C. (2022) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000001093 · Cited by 11
The use of gabapentinoids and opioids and risk of developing opioid-induced respiratory depression among older breast cancer survivors with neuropathic pain
Lakkad, M., Martin, B. C., Li, C., Harrington, S. E., Dayer, L. E., & Painter, J. T. (2023) · Journal of Cancer Survivorship · doi:10.1007/s11764-023-01338-9 · Cited by 13
Small Area Estimation and Hotspot Identification of Opioid Use Disorder among Military Veterans Living in the Southern United States
Albright, D. L., McDaniel, J. T., Kertesz, S. G., Seal, D. W., Prather, K., English, T. M., & Laha‐Walsh, K. (2019) · Substance Abuse · doi:10.1080/08897077.2019.1703066 · Cited by 11
Trends in Urine Drug Testing Among Long-term Opioid Users, 2012–2018
Taha, S. A., Westra, J. R., Raji, M. A., & Kuo, Y. (2020) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2020.10.011 · Cited by 11
Post-traumatic stress disorder and risky opioid use among persons living with HIV and chronic pain
Bhatraju, E. P., Liebschutz, J. M., Lodi, S., Forman, L. S., Lira, M. C., Kim, T. W., Colasanti, J. A., del Rı́o, C., Samet, J. H., & Tsui, J. I. (2021) · AIDS Care · doi:10.1080/09540121.2021.1876838 · Cited by 11
Observational evidence that urbanisation and neighbourhood deprivation are associated with escalation in chronic pharmacological pain treatment: a longitudinal population-based study in the Netherlands
Leue, C., Buijs, S. J. E., Strik, J. J. M. H., Lousberg, R. L., Smit, J., van Kleef, M., & van Os, J. (2012) · BMJ Open · doi:10.1136/bmjopen-2011-000731 · Cited by 11
Combat exposure is associated with cortical thickness in Veterans with a history of chronic pain
Corbo, V., Salat, D. H., Powell, M. A., Milberg, W., & McGlinchey, R. E. (2016) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2016.02.003 · Cited by 11
Utilization of complementary and integrative health services and opioid therapy by patients receiving Veterans Health Administration pain care
Ashrafioun, L., Allen, K. D., & Pigeon, W. R. (2018) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2018.05.008 · Cited by 11
What are we treating with opioid and sedative-hypnotic combination therapy?
Sullivan, M. D. (2015) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.3821 · Cited by 11
Reducing Long-term Opioid Use in the Veterans Health Administration
Minegishi, T., & Frakt, A. B. (2018) · Journal of General Internal Medicine · doi:10.1007/s11606-018-4352-7 · Cited by 11
Risk Factors for Chronic Prescription Opioid Use in Multiple Sclerosis
Turner, A. P., Arewasikporn, A., Hawkins, E. J., Suri, P., Burns, S. P., Leipertz, S. L., & Haselkorn, J. K. (2023) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2023.04.012 · Cited by 10
The POPPY Research Programme protocol: investigating opioid utilisation, costs and patterns of extramedical use in Australia
Degenhardt, L. J., Blanch, B., Gisev, N., Larance, B., & Pearson, S. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-007030 · Cited by 10
Drug Addiction in Pregnancy: Disease Not Moral Failure
Maguire, D. J. (2013) · Neonatal Network The Journal of Neonatal Nursing · doi:10.1891/0730-0832.33.1.11 · Cited by 10
Opioid and Nonpharmacologic Treatments Among Soldiers With Chronic Pain and Posttraumatic Stress Disorder
Saadoun, M., Bauer, M. R., Adams, R. S., Highland, K. B., & Larson, M. J. (2021) · Psychiatric Services · doi:10.1176/appi.ps.201900303 · Cited by 10
Qualitative Evaluation Informs the Implementation of a Telehealth Program to Manage Chronic Pain
McHugh, M., Fowler, C. A., Philbin, S. E., Schneider, T., Ballistrea, L. M., Klanchar, S. A., Smith, B., Benzinger, R. C., French, D. D., Saenger, M. S., et al. (2024) · Journal of Pain · doi:10.1016/j.jpain.2024.02.007 · Cited by 12
Opioid dosing trends over eight years among US Veterans with musculoskeletal disorders after returning from service in support of recent conflicts
Han, L., Allore, H. G., Goulet, J. L., Bathulapalli, H., Skanderson, M., Brandt, C., Haskell, S. G., & Krebs, E. E. (2017) · Annals of Epidemiology · doi:10.1016/j.annepidem.2017.08.015 · Cited by 10
Self-citation
Literature Review of Research on Chronic Pain and Yoga in Military Populations
Miller, S., Gaylord, S. A., Buben, A., Brintz, C., Olmsted, K. R., Asefnia, N., & Bartoszek, M. W. (2017) · Medicines · doi:10.3390/medicines4030064 · Cited by 10
Gender-Stratified Prevalence of Psychiatric and Pain Diagnoses in a Primary Care Patient Sample with Fibromyalgia
Wan, B. P., Gebauer, S., Salas, J., Jacobs, C. K., Breeden, M. A., & Scherrer, J. F. (2019) · Pain Medicine · doi:10.1093/pm/pnz084 · Cited by 11
Dose of Exercise Therapy Among Active Duty Soldiers With Chronic Pain Is Associated With Lower Risk of Long-Term Adverse Outcomes After Linking to the Veterans Health Administration
Meerwijk, E. L., Adams, R. S., Larson, M. J., Highland, K. B., & Harris, A. H. S. (2022) · Military Medicine · doi:10.1093/milmed/usac074 · Cited by 10
Prevalence of chronic pain and related risk factors in military veterans: a systematic review protocol
VanDenKerkhof, E. G., Carley, M. E., Hopman, W. M., Ross‐White, A., & Harrison, M. B. (2014) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2014-1273 · Cited by 10
Opioid Use as a Predictor of Health Care Use and Pain Outcomes: Analysis of Clinical Trial Data
Krebs, E. E., Kroenke, K., Wu, J., Bair, M. J., Kozak, M. A., & Yu, Z. (2016) · Pain Medicine · doi:10.1093/pm/pnw002 · Cited by 10
Self-citation
21stCentury Cures for the Opioid Crisis: Promise, Impact, and Missed Opportunities
Beletsky, L. A. (2018) · American Journal of Law & Medicine · doi:10.1177/0098858818789417 · Cited by 10
Psychiatry and the Opioid Overdose Crisis
Madras, B. K., & Connery, H. S. (2019) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.20190003 · Cited by 10
Does early physical therapy intervention reduce opioid burden and improve functionality in the management of chronic lower back pain?
Martin, S., Tallian, K. B., Nguyen, V. T., Dyke, J. V., & Sikand, H. (2020) · Mental Health Clinician · doi:10.9740/mhc.2020.07.215 · Cited by 10
Evaluation of a non‐pharmacological interdisciplinary pain rehabilitation and functional restoration program for chronic pain in veterans
Ward, R., Rauch, S. A. M., Axon, R. N., & Saenger, M. S. (2023) · Health Services Research · doi:10.1111/1475-6773.14062 · Cited by 9
The integration of harm reduction services in the Veterans Health Administration (VHA): a qualitative analysis of barriers and facilitators
Harvey, L. H., Sliwinski, S. K., Flike, K., Boudreau, J., Gifford, A. L., Branch‐Elliman, W., & Hyde, J. K. (2023) · Journal of Addictive Diseases · doi:10.1080/10550887.2023.2210021 · Cited by 9
Naloxone Distribution and Training for Patients with High-Risk Opioid Use in a Veterans Affairs Community-Based Primary Care Clinic
Raffel, K. E., Beach, L. Y., Lin, J. K., Berchuck, J. E., Abram, S., Markle, E. A., & Patel, S. (2018) · The Permanente Journal · doi:10.7812/tpp/17-179 · Cited by 9
Prescribing Opioids for Chronic Noncancer Pain in Primary Care: Risk Assessment
GORDON, A. S., Cone, E. J., DePriest, A. Z., Axford-Gatley, R. A., & Passik, S. D. (2014) · Postgraduate Medicine · doi:10.3810/pgm.2014.09.2810 · Cited by 9
Chronic opioid therapy and its utility in different populations
Ballantyne, J. C. (2012) · Pain · doi:10.1016/j.pain.2012.07.015 · Cited by 9
Veteran Interactive Cases to Reinforce Service (VICTORS): Standardized Patient Assessment of Veteran-Centered Care
Lypson, M. L., Ravindranath, D., Ross, P. T., Pfeiffer, P., Griggs, J. J., Buckler, S., Whitman, L., Tremblay, A. S., Weiner, S. J., & Fitzgerald, J. T. (2016) · MedEdPORTAL · doi:10.15766/mep_2374-8265.10326 · Cited by 9
The Paucity of Attention to Narcotics Anonymous in Current Public, Professional, and Policy Responses to Rising Opioid Addiction
White, W. L., Galanter, M. S., Humphreys, K. N., & Kelly, J. F. (2016) · Alcoholism Treatment Quarterly · doi:10.1080/07347324.2016.1217712 · Cited by 9
Consumo de fármacos opiáceos en la ciudad de Madrid: Factores sanitarios y sociodemográficos asociados
Pérez, E. J. P., Morales-Alonso, S., Álvarez-Crespo, B., & Benítez-Robredo, M. T. (2020) · Adicciones · doi:10.20882/adicciones.1335 · Cited by 9

Authors: Seal, K. H., Shi, Y., Cohen, G., Cohen, B. E., Maguen, S., Krebs, E. E., & Neylan, T. C.
Affiliations: San Francisco VA Medical Center (US)
University of California, San Francisco (US)
Indiana University (US)
Corresponding author: Seal, Karen H.
ORCID: Seal, Karen H.
Shi, Ying
Cohen, Gregory
Cohen, Beth E.
Maguen, Shira
Krebs, Erin E.
Neylan, Thomas C.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 2012-03-07
Volume: 307
Issue: 9
Pages: 940-7
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.2012.234
OpenAlex: W1972850166
Cited by: 515
References: 49
Citations by year: 2026: 7 · 2025: 17 · 2024: 19 · 2023: 33 · 2022: 31 · 2021: 36 · 2020: 42 · 2019: 52 · 2018: 59 · 2017: 47 · 2016: 44 · 2015: 37 · 2014: 34 · 2013: 38 · 2012: 16
FWCI: 38.64
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Funders: National Heart, Lung, and Blood Institute (K23HL094765)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords: opioid use, post-traumatic stress disorder, mental illness, Iraq and Afghanistan veterans, opioid overdose, opioid refills, sedative-hypnotic drugs, adverse clinical outcomes, veterans' health care, pain management, opioid prescribing practices, opioid-related deaths, opioid-related hospitalizations, opioid-related emergency department visits
MeSH terms: Adult, Analgesics, Opioid, Mental Disorders, Female, Humans, Male, Opioid-Related Disorders, Pain, Retrospective Studies, Risk, Stress Disorders, Post-Traumatic, United States, Veterans, Cohort Studies, Iraq War, 2003-2011, Prescription Drugs, Afghan Campaign 2001-, Drug Overdose

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Association of Mental Health Disorders With Prescription Opioids and High-Risk Opioid Use in US Veterans of Iraq and Afghanistan

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks