The Role of 5α-Reductase Inhibition in Men Receiving Testosterone Replacement Therapy

The Development of Human Benign Prostatic Hyperplasia with Age

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The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia

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Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society Clinical Practice Guideline

Bhasin, S., Cunningham, G. R., Hayes, F. J., Matsumoto, A. M., Snyder, P. J., Swerdloff, R. S., & Montori, V. M. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2354 · Cited by 1,954 · see citing works

Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts Male Aging Study

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The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

Gormley, G. J., Stoner, E., Bruskewitz, R. C., Imperato‐McGinley, J., Walsh, P. C., McConnell, J. D., Andriole, G. L., Geller, J., Bracken, B. R., Tenover, J. L., et al. (1992) · New England Journal of Medicine · doi:10.1056/nejm199210223271701 · Cited by 1,104 · see citing works

Adverse Effects of Testosterone Therapy in Adult Men: A Systematic Review and Meta-Analysis

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Effects of Testosterone Replacement in Hypogonadal Men1

Snyder, P. J., Peachey, H., Berlin, J. A., Hannoush, P., Haddad, G., Dlewati, A., Santanna, J., Loh, L., Lenrow, D. A., Holmes, J. H., et al. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6731 · Cited by 608 · see citing works

Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T

Page, S. T., Amory, J. K., Bowman, F. D., Anawalt, B. D., Matsumoto, A. M., Bremner, W. J., & Tenover, J. L. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1933 · Cited by 566 · see citing works

Exogenous Testosterone or Testosterone with Finasteride Increases Bone Mineral Density in Older Men with Low Serum Testosterone

Amory, J. K., Watts, N. B., Easley, K. A., Sutton, P. R., Anawalt, B. D., Matsumoto, A. M., Bremner, W. J., & Tenover, J. L. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031110 · Cited by 475 · see citing works

Effect of Testosterone Replacement Therapy on Prostate Tissue in Men With Late-Onset Hypogonadism: A Randomized Controlled Trial

Marks, L. S., Mazer, N. A., Mostaghel, E., Hess, D. L., Dorey, F. J., Epstein, J. I., Veltri, R. W., Makarov, D. V., Partin, A. W., Bostwick, D. G., et al. (2006) · JAMA · doi:10.1001/jama.296.19.2351 · Cited by 400 · see citing works

Long-Term Pharmacokinetics of Transdermal Testosterone Gel in Hypogonadal Men 1

Swerdloff, R. S., Wang, C., Cunningham, G. R., Dobs, A. S., Iranmanesh, A., Matsumoto, A. M., Snyder, P. J., Weber, T. J., Longstreth, J. A., & Berman, N. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.12.7045 · Cited by 343 · see citing works

A Double-Blind, Placebo-Controlled, Randomized Clinical Trial of Transdermal Dihydrotestosterone Gel on Muscular Strength, Mobility, and Quality of Life in Older Men with Partial Androgen Deficiency

Ly, L. P., Jimenez, M., Zhuang, T. N., Celermajer, D. S., Conway, A. J., & Handelsman, D. J. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.9.7821 · Cited by 241 · see citing works

Pharmacokinetics of Transdermal Testosterone Gel in Hypogonadal Men: Application of Gel at One Site Versus Four Sites: A General Clinical Research Center Study

Wang, C., Berman, N., Longstreth, J. A., Chuapoco, B., Hull, L., Steiner, B., Faulkner, S., Dudley, R. E., & Swerdloff, R. S. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.3.6437 · Cited by 189 · see citing works

Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production: A Randomized Controlled Trial

Bhasin, S., Travison, T. G., Storer, T. W., Lakshman, K., Kaushik, M., Mazer, N. A., Ngyuen, A.-H., Davda, M. N., Jara, H., Aakil, A., et al. (2012) · JAMA · doi:10.1001/jama.2012.227 · Cited by 152 · see citing works

Testosterone therapy in men with androgen deficiency syndromes: An endocrine society clinical practice guideline (Journal of Clinical Endocrinology and Metabolism (2010) 95, (2536-2559))

Bhasin, S., Cunningham, G. R., Hayes, F. J., Matsumoto, A. M., Snyder, P. J., Swerdloff, R. S., & Montori, V. M. (2010) · The Journal of Clinical Endocrinology & Metabolism · Cited by 149 · see citing works

Long-Term Effects of Dihydrotestosterone Treatment on Prostate Growth in Healthy, Middle-Aged Men Without Prostate Disease

Idan, A., Griffiths, K. A., Harwood, D. T., Seibel, M. J., Turner, L., Conway, A. J., & Handelsman, D. J. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-153-10-201011160-00004 · Cited by 89 · see citing works

The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men

Amory, J. K., Anawalt, B. D., Matsumoto, A. M., Page, S. T., Bremner, W. J., Wang, C., Swerdloff, R. S., & Clark, R. V. (2008) · The Journal of Urology · doi:10.1016/j.juro.2008.01.145 · Cited by 85 · see citing works

Dihydrotestosterone Administration Does Not Increase Intraprostatic Androgen Concentrations or Alter Prostate Androgen Action in Healthy Men: A Randomized-Controlled Trial

Page, S. T., Lin, D. W., Mostaghel, E. A., Marck, B. T., Wright, J. L., Wu, J. D., Amory, J. K., Nelson, P. S., & Matsumoto, A. M. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1865 · Cited by 77 · see citing works

Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and its Clinical Significance: A Prospective Clinical Study

Uygur, M. C., Arık, A. İ., Altuğ, U., & Erol, D. (1998) · Steroids · doi:10.1016/s0039-128x(98)00005-1 · Cited by 60 · see citing works

Effects of finasteride on serum testosterone and body mass index in men with benign prostatic hyperplasia

Roehrborn, C. G., Lee, M., Meehan, A. G., & Waldstreicher, J. (2003) · Urology · doi:10.1016/s0090-4295(03)00661-7 · Cited by 56 · see citing works

Association Between 5-α Reductase Inhibition and Risk of Hip Fracture

Jacobsen, S. J. (2008) · JAMA · doi:10.1001/jama.300.14.1660 · Cited by 41 · see citing works

Erythrocytosis Following Testosterone Therapy

Ohlander, S. J., Varghese, B., & Pastuszak, A. W. (2018) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2017.04.001 · Cited by 168 · see citing works

Expression of 5α- and 5β-reductase in spinal cord and muscle of birds with different courtship repertoires

Fuxjager, M. J., Schuppe, E. R., Hoang, J., Chew, J. G., Shah, M., & Schlinger, B. A. (2016) · Frontiers in Zoology · doi:10.1186/s12983-016-0156-y · Cited by 24 · see citing works

The role of the androgen receptor in the pathogenesis of obesity and its utility as a target for obesity treatments

Venkatesh, V. S., Grossmann, M., Zajac, J. D., & Davey, R. A. (2022) · Obesity Reviews · doi:10.1111/obr.13429 · Cited by 22 · see citing works

Elevated Dihydrotestosterone is Associated with Testosterone Induced Erythrocytosis

Aghazadeh, M. A., Pastuszak, A. W., Johnson, W. G., McIntyre, M. G., Hsieh, T., & Lipshultz, L. I. (2015) · The Journal of Urology · doi:10.1016/j.juro.2015.01.038 · Cited by 19 · see citing works

Testosterone replacement therapy: clinical considerations

Luther, P. M., Spillers, N. J., Talbot, N. C., Sinnathamby, E. S., Ellison, D., Kelkar, R. A., Ahmadzadeh, S., Shekoohi, S., & Kaye, A. D. (2024) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2024.2306832 · Cited by 17 · see citing works

Improvements in body composition, cardiometabolic risk factors and insulin sensitivity with trenbolone in normogonadic rats

Donner, D. G., Beck, B. R., Bulmer, A. C., Lam, A. K.-Y., & Toit, E. F. D. (2014) · Steroids · doi:10.1016/j.steroids.2014.12.017 · Cited by 8 · see citing works

Influence of dutasteride treatment on serum hormone levels and aging male symptoms in patients with benign prostatic enlargement

Maeda, T., Kikuchi, E., Hasegawa, M., Homma, K., Ando, T., Suzuki, K., Kaneko, G., Mizuno, R., Miyajima, A., & Oya, M. (2017) · International Journal of Urology · doi:10.1111/iju.13470 · Cited by 6 · see citing works

The effect of 5α-reductase inhibitors on prostate growth in men receiving testosterone replacement therapy: a systematic review and meta-analysis

Cui, Y., Zong, H., Yang, C., Yan, H., & Zhang, Y. (2013) · International Urology and Nephrology · doi:10.1007/s11255-013-0477-0 · Cited by 6 · see citing works

Therapeutic Effects of Selective Androgen Receptor Modulation in the Treatment of Cardiac, Metabolic and Bone Pathologies Associated with Androgen Decline and Obesity

Donner, D. G. (2015) · Griffith Research Online · doi:10.13140/rg.2.1.1191.1761

Testosterone and 5 alpha-reductase

Maeda, T., Kikuchi, E., & Oya, M. (2012) · Journal of Clinical Urology

Roles of 5 α-reductase in male reproduction

Xiao, W. (2003) · Journal of reproductive medicine

5α‐Reductase Inhibitors

Rittmaster, R. S. (1997) · Journal of Andrology · doi:10.1002/j.1939-4640.1997.tb02434.x · Cited by 62 · see citing works

Study on the effects of 5-alpha reductase inhibitor on hormones and semen parameters in men

Lim, K.-T., Choo, C., Lim, K.-S., Lee, W.-D., & Lim, J. (2025) · Endocrine Abstracts · doi:10.1530/endoabs.109.p220

Persistent Sexual Dysfunction and 5 Alpha Reductase Inhibitors

Uribe, J. F. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02676.x