The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Seven Questions for Personalized Medicine
Abstract
Personalized or precision medicine maintains that medical care and public health will be radically transformed by prevention and treatment programs more closely targeted to the individual patient. These interventions will be developed by sequencing more genomes, creating bigger biobanks, and linking biological information to health data in electronic medical records (EMRs) or obtained by monitoring technologies. Yet the assumptions underpinning personalized medicine have largely escaped questioning. In this Viewpoint, we seek to stimulate a more balanced debate by posing 7 questions for the advocates of personalized medicine.
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Cites
Clinical Use of Ibuprofen Is Associated with Slower FEV 1 Decline in Children with Cystic Fibrosis
Konstan, M. W., Schluchter, M. D., Xue, W., & Davis, P. B. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200702-181oc · Cited by 178
Personalized Genetic Risk Counseling to Motivate Diabetes Prevention
Grant, R. W., OʼBrien, K., Waxler, J. L., Vassy, J. L., Delahanty, L. M., Bissett, L., Green, R. C., Stember, K. G., Guiducci, C., Park, E. R., et al. (2012) · Diabetes Care · doi:10.2337/dc12-0884 · Cited by 152
Genotype-Guided vs Clinical Dosing of Warfarin and Its Analogues
Stergiopoulos, K., & Brown, D. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2014.2368 · Cited by 125
Aligning incentives to fulfil the promise of personalised medicine
Dzau, V. J., Ginsburg, G. S., Nuys, K. V., Agus, D. B., & Goldman, D. P. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60722-x · Cited by 82
CYP2D6 Genotype and Tamoxifen Response for Breast Cancer: A Systematic Review and Meta-Analysis
Lum, D. W. K., Perel, P., Hingorani, A. D., & Holmes, M. V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076648 · Cited by 50
Cited by
The “All of Us” Research Program
The All of Us Research Program Investigators (2019) · New England Journal of Medicine · doi:10.1056/nejmsr1809937 · Cited by 2,440
Patient-Derived Organoids Predict Chemoradiation Responses of Locally Advanced Rectal Cancer
Yao, Y., Xu, X., Yang, L., Zhu, J., Wan, J., Shen, L., Xia, F., Fu, G., Deng, Y., Pan, M., et al. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2019.10.010 · Cited by 755
OM Forum—Healthcare Operations Management: A Snapshot of Emerging Research
Dai, T., & Tayur, S. (2020) · Manufacturing & Service Operations Management · doi:10.1287/msom.2019.0778 · Cited by 147
von Thiele Schwarz, U., Aarons, G. A., & Hasson, H. (2019) · BMC Health Services Research · doi:10.1186/s12913-019-4668-y · Cited by 134
Goldfeder, R. L., Wall, D. P., Khoury, M. J., Ioannidis, J. P. A., & Ashley, E. A. (2017) · American Journal of Epidemiology · doi:10.1093/aje/kww224 · Cited by 75
Metadata
- Authors
- Joyner, M. J., & Paneth, N.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2015-09-08
- Volume
- 314
- Issue
- 10
- Pages
- 999
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W1518730520
- Cited by
- 252
- References
- 5
- FWCI
- 41.41
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
