The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Adjustment for Baseline Characteristics in Randomized Clinical Trials
Open accessAbstract
This Guide to Statistics and Methods provides an overview of the use of adjustment for baseline characteristics in the analysis of randomized clinical trials and emphasizes several important considerations.
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“We also presented the results of a multivariable analysis, which adjusted for baseline variables known to predict abstinence and did not interact with treatment, including nicotine dependence and quit attempts [32].”
From Personalized chat‐based support for smoking cessation among smokers with mental health symptoms in the workplace: A randomized controlled trial. (2025) · cites this paper as [32]
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Cites
Kahan, B. C., Jairath, V., Doré, C. J., & Morris, T. P. (2014) · Trials · doi:10.1186/1745-6215-15-139 · Cited by 497
Adjustments for Center in Multicenter Studies: An Overview
Localio, A. R., Berlin, J. A., Have, T. R. T., & Kimmel, S. E. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-135-2-200107170-00012 · Cited by 442
Randomization in Clinical Trials: Permuted Blocks and Stratification
Broglio, K. (2018) · JAMA · doi:10.1001/jama.2018.6360 · Cited by 243
Zampieri, F. G., Machado, F. R., Biondi, R., Freitas, F. G. R., Veiga, V. C., Figueiredo, R. C., Lovato, W. J., Amêndola, C. P., Neto, A. S., Paranhos, J. L. D. R., et al. (2021) · JAMA · doi:10.1001/jama.2021.11684 · Cited by 221
Planning a method for covariate adjustment in individually randomised trials: a practical guide
Morris, T. P., Walker, A. S., Williamson, E. J., & White, I. R. (2022) · Trials · doi:10.1186/s13063-022-06097-z · Cited by 97
Estimands, Estimators, and Estimates
Little, R. J. A., & Lewis, R. J. (2021) · JAMA · doi:10.1001/jama.2021.2886 · Cited by 50
Mistry, E. A., Yeatts, S. D., Khatri, P., Mistry, A. M., Detry, M. A., Viele, K., Harrell, F. E., & Lewis, R. J. (2022) · Stroke · doi:10.1161/strokeaha.121.034859 · Cited by 45
Covariate Adjustment in Cardiovascular Randomized Controlled Trials
Pirondini, L., Gregson, J., Owen, R., Collier, T. J., & Pocock, S. (2022) · JACC Heart Failure · doi:10.1016/j.jchf.2022.02.007 · Cited by 23
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Pittas, A. G., Kawahara, T., Jorde, R., Dawson‐Hughes, B., Vickery, E. M., Angellotti, E., Nelson, J., Trikalinos, T. A., & Balk, E. M. (2023) · Annals of Internal Medicine · doi:10.7326/m22-3018 · Cited by 186
Interpreting Randomized Controlled Trials
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Effects of a Mobile App to Promote Social Participation on Older Adults: Randomized Controlled Trial
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Kopf-Beck, J., Müller, C. L., Tamm, J., Fietz, J., Rek, N., Just, L., Spock, Z. I., Weweck, K., Takano, K., Rein, M., et al. (2024) · Psychotherapy and Psychosomatics · doi:10.1159/000535492 · Cited by 30
Metadata
- Authors
- Holmberg, M. J., & Andersen, L. W.
- Affiliations
- Aarhus University (DK)
- Corresponding author
- Andersen, Lars W.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2022-12-06
- Volume
- 328
- Issue
- 21
- Pages
- 2155
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W4309183852
- Cited by
- 161
- References
- 8
- Citations by year
- 2026: 55 · 2025: 45 · 2024: 40 · 2023: 21
- FWCI
- 19.69
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Keywords
- baseline characteristics, adjustment, randomized controlled trials, covariate adjustment, treatment effect estimation, confounding
- MeSH terms
- Research Design, Randomized Controlled Trials as Topic
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