Cited by 95Thyroid Disorders and TreatmentsThyroid and Parathyroid SurgeryPharmaceutical Practices and Patient Outcomes

The DOI matches its Crossref record, with a small difference in title or year; 16 of the 16 references it cites were found in a registry or an index.

The Aging Thyroid: The Use of Thyroid Hormone in Older Persons

Sawin, Clark T.·1989·JAMA

DOI 10.1001/jama.261.18.2653

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Abstract

The overall prevalence of thyroid hormone use in an unselected population of older adults (n = 2575; average age, 68.6 years) was 6.9% (10.0% in women and 2.3% in men). Eighty-one percent of women taking it were doing so for appropriate indications, eg, hypothyroidism, while 12% were not, eg, for obesity or high serum cholesterol; more men (29%) were taking it inappropriately. Inappropriate use was associated with desiccated thyroid more than with thyroxine. After follow-up averaging 6.9 years, 58% of inappropriate users were still taking it. Underuse also occurred. Thirty-seven percent of those definitely hypothyroid had a clearly elevated serum thyrotropin level (greater than 10 mU/L) despite thyroid therapy. Thyroid therapy is common in the elderly; most is appropriate. When inappropriate use occurs, it is more common in men and more often associated with desiccated thyroid, still commonly used in this age group. In chronic users of thyroid hormone, it is important to review currently appropriate indications and to measure serum thyrotropin levels to assess the adequacy of treatment of primary hypothyroidism.

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Ocampo, E. L., & Surks, M. I. (1997) · doi:10.1007/978-1-4757-2594-0_9
Recherche d'un lien entre les diabétiques de type 2 présentant un syndrome métabolique, et les hypothyroïdies, frustes ou avérées, en Aquitaine
Moulinie, L. (2015) · HAL

Authors: Sawin, C. T.
Affiliations: United States Department of Veterans Affairs (US)
Corresponding author: Sawin, Clark T.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 1989-05-12
Volume: 261
Issue: 18
Pages: 2653
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.261.18.2653
OpenAlex: W2043303113
Cited by: 94
References: 16
Citations by year: 2023: 2 · 2021: 1 · 2019: 2 · 2017: 2 · 2016: 5 · 2015: 5 · 2014: 2 · 2013: 3 · 2012: 4
FWCI: 3.03
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
Keywords: thyroid hormone replacement, older adults, hypothyroidism, inappropriate prescribing, desiccated thyroid, levothyroxine, serum thyrotropin, sex differences in prescribing
MeSH terms: Age Factors, Aged, Drug Utilization, Female, Follow-Up Studies, Goiter, Humans, Hypercholesterolemia, Hypothyroidism, Male, Sex Factors, Thyroid Diseases, Thyroid Hormones, Cohort Studies

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The Aging Thyroid: The Use of Thyroid Hormone in Older Persons

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