The DOI matches its OpenAlex record; 1 of the 1 references it cites were found in a registry or an index.
Tubal ligation, hysterectomy, and risk of ovarian cancer. A prospective study
Abstract
OBJECTIVE: To assess whether tubal ligation and hysterectomy affect subsequent risk of ovarian cancer. DESIGN: Prospective cohort study with 12 years of follow-up. SETTING: United States, multistate. PARTICIPANTS: A total of 121,700 female registered nurses who were 30 to 55 years of age in 1976; the follow-up rate was 90% as of 1988. MAIN OUTCOME MEASURE: Ovarian cancer of epithelial origin confirmed by medical record review. RESULTS: We observed a strong inverse association between tubal ligation and ovarian cancer, which persisted after adjustment for age, oral contraceptive use, parity, and other ovarian cancer risk factors (multivariate relative risk [RR], 0.33; 95% confidence interval [CI], 0.16 to 0.64). The association was similar when we assessed tubal ligation status at the baseline questionnaire and excluded cases in the first 4 years to eliminate any possible short-term decrease in risk due to screening of the ovaries during ligation surgery. We noted a weaker inverse association between simple hysterectomy and ovarian cancer (RR, 0.67; 95% CI, 0.45 to 1.00). Neither vasectomy nor condom use by a partner was associated with risk of ovarian cancer. CONCLUSIONS: These data indicate that tubal ligation, and perhaps hysterectomy, may substantially reduce risk of epithelial ovarian cancer.
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Cites
D'Agostino, R. B., Lee, M., Belanger, A. J., Cupples, L. A., Anderson, K., & Kannel, W. B. (1990) · Statistics in Medicine · doi:10.1002/sim.4780091214 · Cited by 798
Cited by
Epidemiology of ovarian cancer: a review
Brett M., R., Brett M., R., Jennifer B., P., Thomas A., S., Jennifer B., P., & Thomas A., S. (2017) · Cancer Biology & Medicine · doi:10.20892/j.issn.2095-3941.2016.0084 · Cited by 1,524
Parker, W. H., Broder, M. S., Chang, E., Feskanich, D., Farquhar, C., Liu, Z., Shoupe, D., Berek, J. S., Hankinson, S., & Manson, J. E. (2009) · Obstetrics & Gynecology · doi:10.1097/aog.0b013e3181a11c64 · Cited by 640
Self-citationHennessy, B. T., Coleman, R. L., & Markman, M. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61338-6 · Cited by 640
Parity, age at first childbirth, and risk of ovarian cancer
Adami, H.-O., Lambe, M., Persson, I., Ekbom, A., Adami, H. O., Hsieh, C. C., Trichopoulos, D., Ekbom, A., Lambe, M., Leon, D., et al. (1994) · The Lancet · doi:10.1016/s0140-6736(94)90749-8 · Cited by 347
Nelson, H. D., Huffman, L. H., Fu, R., & Harris, E. L. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-143-5-200509060-00012 · Cited by 346
Metadata
- Authors
- Hankinson, S. E.
- Venue
- JAMA
- Publisher
- American Medical Association
- Published
- 1993-12-15
- Volume
- 270
- Issue
- 23
- Pages
- 2813-2818
- ISSN
- 0002-9955 (ISSN-L)
- OpenAlex
- W4235941292
- Cited by
- 330
- References
- 1
- FWCI
- 11.40
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hankinson, S. E. (1993). Tubal ligation, hysterectomy, and risk of ovarian cancer. A prospective study. JAMA. https://doi.org/10.1001/jama.270.23.2813
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
