The DOI matches its Crossref record; 284 of the 284 references it cites were found in a registry or an index.
Epidemiology of ovarian cancer: a review
Open accessAbstract
Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the world and the tenth most common in China. Epithelial OC is the most predominant pathologic subtype, with five major histotypes that differ in origination, pathogenesis, molecular alterations, risk factors, and prognosis. Genetic susceptibility is manifested by rare inherited mutations with high to moderate penetrance. Genome-wide association studies have additionally identified 29 common susceptibility alleles for OC, including 14 subtype-specific alleles. Several reproductive and hormonal factors may lower risk, including parity, oral contraceptive use, and lactation, while others such as older age at menopause and hormone replacement therapy confer increased risks. These associations differ by histotype, especially for mucinous OC, likely reflecting differences in etiology. Endometrioid and clear cell OC share a similar, unique pattern of associations with increased risks among women with endometriosis and decreased risks associated with tubal ligation. OC risks associated with other gynecological conditions and procedures, such as hysterectomy, pelvic inflammatory disease, and polycystic ovarian syndrome, are less clear. Other possible risk factors include environmental and lifestyle factors such as asbestos and talc powder exposures, and cigarette smoking. The epidemiology provides clues on etiology, primary prevention, early detection, and possibly even therapeutic strategies.
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Cites
2 retracted
Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2
Li, L., Mao, X., Qin, X., Zhou, M., Xing, H., Dong, F., Jiang, X., & ZHUANG, W. (2016) · Oncology Letters · doi:10.3892/ol.2016.4607 · Cited by 16
RetractedLi, L., Mao, X., Qin, X., Zhou, M., Xing, H., Dong, F., Jiang, X., & Zhuang, W. (2019) · Oncology Letters · doi:10.3892/ol.2019.10108 · Cited by 12
RetractedCancer statistics in China, 2015
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Cited by
Lheureux, S., Gourley, C., Vergote, I., & Oza, A. M. (2019) · The Lancet · doi:10.1016/s0140-6736(18)32552-2 · Cited by 1,919
Ovarian cancer in the world: epidemiology and risk factors
Momenimovahed, Z., Tiznobaik, A., Taheri, S., & Salehiniya, H. (2019) · International Journal of Women's Health · doi:10.2147/ijwh.s197604 · Cited by 912
The Role of Tumor-Associated Macrophages in the Progression and Chemoresistance of Ovarian Cancer
Nowak, M., & Klink, M. (2020) · Cells · doi:10.3390/cells9051299 · Cited by 287
Hao, J., Kim, Y., Mallavarapu, T., Oh, J. H., & Kang, M. (2019) · BMC Medical Genomics · doi:10.1186/s12920-019-0624-2 · Cited by 82
The Endometriotic Tumor Microenvironment in Ovarian Cancer
Wendel, J. R. H., Wang, X., & Hawkins, S. M. (2018) · Cancers · doi:10.3390/cancers10080261 · Cited by 51
Metadata
- Authors
- Brett M., R., Brett M., R., Jennifer B., P., Thomas A., S., Jennifer B., P., & Thomas A., S.
- Venue
- Cancer Biology & Medicine
- Publisher
- China Anti-cancer Association
- Published
- 2017
- Volume
- 14
- Issue
- 1
- Pages
- 9-32
- ISSN
- 2095-3941 (ISSN-L)
- OpenAlex
- W2594404528
- Cited by
- 1,524
- References
- 284
- FWCI
- 119.20
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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