The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.
Educational and Organizational Interventions to Improve the Management of Depression in Primary Care: A Systematic Review
Open accessAbstract
CONTEXT: Depression is commonly encountered in primary care settings yet is often missed or suboptimally managed. A number of organizational and educational strategies to improve management of depression have been proposed. The clinical effectiveness and cost-effectiveness of these strategies have not yet been subjected to systematic review. OBJECTIVE: To systematically evaluate the effectiveness of organizational and educational interventions to improve the management of depression in primary care settings. DATA SOURCES: We searched electronic medical and psychological databases from inception to March 2003 (MEDLINE, PsycLIT, EMBASE, CINAHL, Cochrane Controlled Trials Register, United Kingdom National Health Service Economic Evaluations Database, Cochrane Depression Anxiety and Neurosis Group register, and Cochrane Effective Professional and Organisational Change Group specialist register); conducted correspondence with authors; and used reference lists. Search terms were related to depression, primary care, and all guidelines and organizational and educational interventions. STUDY SELECTION: We selected 36 studies, including 29 randomized controlled trials and nonrandomized controlled clinical trials, 5 controlled before-and-after studies, and 2 interrupted time-series studies. Outcomes relating to management and outcome of depression were sought. DATA EXTRACTION: Methodological details and outcomes were extracted and checked by 2 reviewers. Summary relative risks were, where possible, calculated from original data and attempts were made to correct for unit of analysis error. DATA SYNTHESIS: A narrative synthesis was conducted. Twenty-one studies with positive results were found. Strategies effective in improving patient outcome generally were those with complex interventions that incorporated clinician education, an enhanced role of the nurse (nurse case management), and a greater degree of integration between primary and secondary care (consultation-liaison). Telephone medication counseling delivered by practice nurses or trained counselors was also effective. Simple guideline implementation and educational strategies were generally ineffective. CONCLUSIONS: There is substantial potential to improve the management of depression in primary care. Commonly used guidelines and educational strategies are likely to be ineffective. The implementation of the findings from this research will require substantial investment in primary care services and a major shift in the organization and provision of care.
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“There is a growing body of evidence that shows supporting people to self-manage their health and care can lead to improvements in clinical and humanistic outcomes [12–18], reducing the economic impact of chronic disease and a means of contributing to the sustainability of the global healthcare system.”
From Helping patients help themselves: A systematic review of self-management support strategies in primary health care practice (2019) · cites this paper as [18]
In the citing paper
“Similar trends have been found in existing literature in several contexts that self-management is essential to optimizing clinical and humanistic outcomes for patients with chronic conditions [13, 15, 18, 152–155].”
From Helping patients help themselves: A systematic review of self-management support strategies in primary health care practice (2019) · cites this paper as [18]
In the citing paper
“general practitioners (GP) treatment options are generally limited to medication and referral to counselling or cognitive behavioural therapy (Gilbody et al. , 2003; McPherson and Armstrong, 2012).”
From Do depressed and anxious men do groups? What works and what are the barriers to help seeking? (2014) · cites this paper as Gilbody et al. , 2003
In the citing paper
“Various interventions [1], collaborative care [2], self-management [3,4], and social and community initiatives [5] have shown preliminary evidence of effectiveness in trials in improving outcomes for people experiencing depression and anxiety who may not readily access timely or appropriately targeted care.”
From Development and evaluation of culturally sensitive psychosocial interventions for under-served people in primary care (2014) · cites this paper as [2]
Citations
Cites
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
Jadad, A. R., Moore, R. A., Carroll, D., Jenkinson, C., Reynolds, D. J. M., Gavaghan, D. J., & McQuay, H. J. (1996) · Controlled Clinical Trials · doi:10.1016/0197-2456(95)00134-4 · Cited by 17,582
(1979) · Medical Entomology and Zoology · Cited by 11,252
(1996) · Cited by 6,884
Framework for design and evaluation of complex interventions to improve health
Campbell, M. (2000) · BMJ · doi:10.1136/bmj.321.7262.694 · Cited by 3,474
The world health report 2001 - Mental health: new understanding, new hope
Sayers, J. (2001) · Europe PMC (PubMed Central) · doi:10.1590/s0042-96862001001100014 · Cited by 3,307
Organizing Care for Patients with Chronic Illness
Wagner, E. H., Austin, B. T., & Korff, M. V. (1996) · The Milbank Quarterly · doi:10.2307/3350391 · Cited by 2,877
Unützer, J., Katon, W., Callahan, C. M., Williams, Jr., Hunkeler, E., Harpole, L., Hoffing, M., Della Penna, R. D., Noël, P. H., Lin, E. H. B., et al. (2002) · JAMA · doi:10.1001/jama.288.22.2836 · Cited by 2,405
Ukoumunne, Gulliford, M. C., Chinn, Sterne, & Burney, P. (1999) · Health Technology Assessment · doi:10.3310/hta3050 · Cited by 1,211
Principles of Educational Outreach ('Academic Detailing') to Improve Clinical Decision Making
Soumerai, S. B. (1990) · JAMA · doi:10.1001/jama.1990.03440040088034 · Cited by 1,045
Wells, K. B., Sherbourne, C., Schoenbaum, M., Duan, N., Meredith, L., Unützer, J., Miranda, J., Carney, M. F., & Rubenstein, L. V. (2000) · JAMA · doi:10.1001/jama.283.2.212 · Cited by 1,021
A Multifaceted Intervention to Improve Treatment of Depression in Primary Care
Katon, W. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830100072009 · Cited by 835
Stepped Collaborative Care for Primary Care Patients With Persistent Symptoms of Depression
Katon, W. J., Korff, M. V., Lin, E., Simon, G., Walker, E., Unützer, J., Bush, T. M., Russo, J. E., & Ludman, E. J. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.12.1109 · Cited by 658
Research designs for studies evaluating the effectiveness of change and improvement strategies
Eccles, M. (2003) · Quality and Safety in Health Care · doi:10.1136/qhc.12.1.47 · Cited by 586
Simon, G. E. (2000) · BMJ · doi:10.1136/bmj.320.7234.550 · Cited by 519
Thompson, C., Kinmonth, A., Stevens, L., Pevele, R., Stevens, A., Ostler, K., Pickering, R., Baker, N., Henson, A., Preece, J., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(99)03171-2 · Cited by 489
Hunkeler, E. M. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.8.700 · Cited by 464
Rutz, W., von Knorring, L., & Wålinder, J. (1992) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1992.tb01448.x · Cited by 399
Kessler, D. S., Lloyd, K. R., Lewis, G., Gray, D. P., & Heath, I. (1999) · BMJ · doi:10.1136/bmj.318.7181.436 · Cited by 385
Priest, R. G., Vize, C., Roberts, A., Roberts, M., & Tylee, A. (1996) · BMJ · doi:10.1136/bmj.313.7061.858 · Cited by 385
Randomized Trial of a Depression Management Program in High Utilizers of Medical Care
Katzelnick, D. J. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.4.345 · Cited by 331
Cost-effectiveness of Practice-Initiated Quality Improvement for Depression
Schoenbaum, M., Unützer, J., Sherbourne, C. D., Duan, N., Rubenstein, L. V., Miranda, J. M., Meredith, L. S., Carney, M. F., & Wells, K. B. (2001) · JAMA · doi:10.1001/jama.286.11.1325 · Cited by 330
Routinely administered questionnaires for depression and anxiety: systematic review
Gilbody, S. M., House, A. O., & Sheldon, T. (2001) · BMJ · doi:10.1136/bmj.322.7283.406 · Cited by 328
Self-citationKaton, W., Von Korff, M., Lin, E., & Simon, G. (2001) · General Hospital Psychiatry · doi:10.1016/s0163-8343(01)00136-0 · Cited by 313
Getting Evidence into Practice
Sanderson, I. (2004) · Evaluation · doi:10.1177/1356389004048283 · Cited by 313
Frequency of suicide on Gotland after systematic postgraduate education of general practitioners
Rutz, W., von Knorring, L., & Wålinder, J. (1989) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1989.tb01318.x · Cited by 310
A Randomized Trial of Relapse Prevention of Depression in Primary Care
Katon, W. J., Rutter, C. M., Ludman, E. J., Korff, M. V., Lin, E. H. B., Simon, G., Bush, T. M., Walker, E., & Unützer, J. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.3.241 · Cited by 292
Treatment Costs, Cost Offset, and Cost-Effectiveness of Collaborative Management of Depression
Korff, M. V., Katon, W. J., Bush, T. M., Lin, E. H. B., Simon, G. E., Saunders, K. W., Ludman, E. J., Walker, E. A., & Unützer, J. (1998) · Psychosomatic Medicine · doi:10.1097/00006842-199803000-00005 · Cited by 271
Peveler, R., George, C., Kinmonth, A. L., Campbell, M. J., & Thompson, C. (1999) · BMJ · doi:10.1136/bmj.319.7210.612 · Cited by 255
Achieving Guidelines for the Treatment of Depression in Primary Care
Lin, E. H. B., Katon, W. J., Simon, G. E., Korff, M. V., Bush, T. M., Rutter, C. M., Saunders, K. W., & Walker, A. (1997) · Medical Care · doi:10.1097/00005650-199708000-00008 · Cited by 228
Coleman, E. A., Grothaus, L. C., Sandhu, N., & Wagner, E. H. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb03832.x · Cited by 221
Predictors of Adequacy of Depression Management in the Primary Care Setting
Joo, J. H., Solano, F. X., Mulsant, B. H., Reynolds, C. F., & Lenze, E. J. (2005) · Psychiatric Services · doi:10.1176/appi.ps.56.12.1524 · Cited by 210
Goldberg, H. I., Wagner, E. H., Fihn, S. D., Martin, D. P., Horowitz, C. R., Christensen, D. B., Cheadle, A. D., Diehr, P. H., & Simon, G. (1998) · The Joint Commission Journal on Quality Improvement · doi:10.1016/s1070-3241(16)30367-4 · Cited by 180
Population-based care of depression: Effective disease management strategies to decrease prevalence
Katon, W. J., Korff, M. V., Lin, E. H. B., Unützer, J., Simon, G., Walker, E., Ludman, E. J., & Bush, T. M. (1997) · General Hospital Psychiatry · doi:10.1016/s0163-8343(97)00016-9 · Cited by 164
Long-term Effectiveness of Disseminating Quality Improvement for Depression in Primary Care
Sherbourne, C. D., Wells, K. B., Duan, N., Miranda, J. M., Unützer, J., Jaycox, L. H., Schoenbaum, M., Meredith, L. S., & Rubenstein, L. V. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.7.696 · Cited by 147
Evidence-Based Care For Depression In Managed Primary Care Practices
Rubenstein, L. V., Jackson‐Triche, M., Unützer, J., de Miranda, J. V. M., Minnium, K., Pearson, M. L., & Wells, K. B. (1999) · Health Affairs · doi:10.1377/hlthaff.18.5.89 · Cited by 135
Quality of Care for Primary Care Patients With Depression in Managed Care
Wells, K. B. (1999) · Archives of Family Medicine · doi:10.1001/archfami.8.6.529 · Cited by 120
Cost-effectiveness of a program to prevent depression relapse in primary care
Simon, G. E., Von Korff, M., Ludman, E. J., Katon, W. J., Rutter, C., Unützer, J., Lin, E. H. B., Bush, T., & Walker, E. (2002) · Medical Care · doi:10.1097/00005650-200210000-00011 · Cited by 115
van Eijk, M. E. C., Avorn, J., Porsius, A. J., & de Boer, A. (2001) · BMJ · doi:10.1136/bmj.322.7287.654 · Cited by 111
Implementing practice guidelines for depression: Applying a new framework to an old problem
Cabana, M. D., Rushton, J. L., & Rush, A. J. (2002) · General Hospital Psychiatry · doi:10.1016/s0163-8343(01)00169-4 · Cited by 111
Can Depression Treatment in Primary Care Reduce Disability?: A Stepped Care Approach
Lin, E. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.10.1052 · Cited by 110
Baker, R., Reddish, S., Robertson, N., Hearnshaw, H., & Jones, B. (2001) · Europe PMC (PubMed Central) · Cited by 105
Does physician education on depression management improve treatment in primary care?
Lin, E. H. B., Simon, G. E., Katzelnick, D. J., & Pearson, S. D. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009614.x · Cited by 104
Two-year effects of quality improvement programs on medication management for depression
Unützer, J., Rubenstein, L., Katon, W. J., Tang, L., Duan, N., Lagomasino, I. T., & Wells, K. B. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.10.935 · Cited by 102
The effect of primary care nurse intervention upon older people screened as depressed
Blanchard, M. R., Waterreus, A. J., & Mann, A. H. (1995) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.930100405 · Cited by 99
ROST, K. M., Nutting, P. A., Smith, J. L., & Werner, J. J. (2000) · General Hospital Psychiatry · doi:10.1016/s0163-8343(00)00059-1 · Cited by 97
Worrall, G. J., Ángel, J. M. R., Chaulk, P. C., Clarke, C., & Robbins, M. (1999) · Europe PMC (PubMed Central) · Cited by 92
Lin, E. H. B., Simon, G. E., Katon, W. J., Russo, J. E., Korff, M. V., Bush, T. M., Ludman, E. J., & Walker, E. A. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.4.643 · Cited by 89
Brook, O. H., van Hout, H. P. J., Nieuwenhuyse, H., & Heerdink, E. R. (2002) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00074-3 · Cited by 83
Freemantle, N., Nazareth, I., Eccles, M., Wood, J., & Haines, A. (2002) · PubMed Central · Cited by 82
Recognition and Management of Depression in Primary Care
Barkin, R. L., Schwer, W. A., & Barkin, S. J. (2000) · American Journal of Therapeutics · doi:10.1097/00045391-200007030-00008 · Cited by 76
Improving the recognition and management of depression: is there a role for physician education?
Gerrity, M., Cole, S., Dietrich, A. J., & Barrett, J. E. (1999) · PubMed · Cited by 75
Rollman, B. L., Hanusa, B. H., Gilbert, T., Lowe, H., Kapoor, W. N., & Schulberg, H. C. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.2.189 · Cited by 75
Brown, J. B., Shye, D., McFarland, B. H., Nichols, G. A., Mullooly, J. P., & Johnson, R. E. (2000) · The Joint Commission Journal on Quality Improvement · doi:10.1016/s1070-3241(00)26004-5 · Cited by 73
An evaluation of practice nurses working with general practitioners to treat people with depression.
MANN, A. H., Blizard, R., Murray, J., Smith, J. A., Botega, N. J., MacDonald, E. A., & Wilkinson, G. (1998) · Europe PMC (PubMed Central) · Cited by 71
Changing the psychiatric knowledge of primary care physicians
Andersen, S. M., & Harthorn, B. H. (1990) · General Hospital Psychiatry · doi:10.1016/0163-8343(90)90077-p · Cited by 59
Depression in Primary Care: Detection, Diagnosis, and Treatment
Panel, D. G. (1994) · Journal of the American Academy of Nurse Practitioners · doi:10.1111/j.1745-7599.1994.tb00946.x · Cited by 59
Meredith, L. S., Jackson‐Triche, M., Duan, N., Rubenstein, L. V., Camp, P., & Wells, K. B. (2000) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2000.91149.x · Cited by 54
Wilkinson, G., Allen, P., Marshall, E., Walker, J., Browne, W., & MANN, A. H. (1993) · Psychological Medicine · doi:10.1017/s0033291700039027 · Cited by 49
A CQI intervention to change the care of depression: a controlled study.
Solberg, L. I., Fischer, L. R., Wei, F., Rush, W. A., Conboy, K. S., Davis, T. F., & Heinrich, R. L. (2001) · PubMed · Cited by 43
Ludman, E. J., Korff, M. V., Katon, W. J., Lin, E. H. B., Simon, G., Walker, E., Unützer, J., Bush, T. M., & Wahab, S. (2000) · The International Journal of Psychiatry in Medicine · doi:10.2190/44lk-28e9-rrj5-kqvw · Cited by 42
The burden of psychiatric disorder in primary care
Shah, A. K. (1992) · International Review of Psychiatry · doi:10.3109/09540269209066324 · Cited by 41
Treatment delivery and guidelines in primary care
Peveler, R., & Kendrick, T. (2001) · British Medical Bulletin · doi:10.1093/bmb/57.1.193 · Cited by 39
Arthur, A. J., Jagger, C., Lindesay, J. E. B., & Matthews, R. J. (2002) · Europe PMC (PubMed Central) · Cited by 38
Hampshire depression project: changes in the process of care and cost consequences.
Kendrick, T., Stevens, L., Bryant, A., Goddard, J. R., Stevens, A. J., Raftery, J., & Thompson, C. (2001) · Europe PMC (PubMed Central) · Cited by 32
Implementing practice guidelines.
Anderson, G. (1993) · PubMed · Cited by 31
A Primary Care Intervention for Depression
Smith, J. I., ROST, K. M., Nutting, P. A., Elliott, C. E., & Duan, N. (2000) · The Journal of Rural Health · doi:10.1111/j.1748-0361.2000.tb00482.x · Cited by 27
Bashir, K., Blizard, B., Bosanquet, A., Bosanquet, N., MANN, A. H., & Jenkins, R. (2000) · Europe PMC (PubMed Central) · Cited by 25
Collaborative Management to Achieve Treatment Guidelines: Impact on Depression in Primary Care
Katon, W. (1995) · JAMA · doi:10.1001/jama.1995.03520370068039 · Cited by 6
Kiuttu, J. K. J. (1999) · Nordic Journal of Psychiatry · doi:10.1080/080394899427818 · Cited by 4
Gonzalez-Salvador (1999) · doi:10.1002/(sici)1099-1166(199909)14:9
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An Ultra-Brief Screening Scale for Anxiety and Depression: The PHQ–4
Kroenke, K., Spitzer, R. L., Williams, J. B. W., & Löwe, B. (2009) · Psychosomatics · doi:10.1016/s0033-3182(09)70864-3 · Cited by 4,261
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Alexopoulos, G. S. (2005) · The Lancet · doi:10.1016/s0140-6736(05)66665-2 · Cited by 2,024
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Self-citation
Metadata
- Authors
- Gilbody, S., Whitty, P., Grimshaw, J., & Thomas, R.
- Affiliations
- University of Leeds (GB)
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2003-06-18
- Volume
- 289
- Issue
- 23
- Pages
- 3145
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2086627928
- Cited by
- 749
- References
- 70
- Citations by year
- 2026: 4 · 2025: 14 · 2024: 13 · 2023: 10 · 2022: 3 · 2021: 19 · 2020: 17 · 2019: 19 · 2018: 19 · 2017: 26 · 2016: 24 · 2015: 26 · 2014: 46 · 2013: 43 · 2012: 35
- FWCI
- 65.91
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- depression, primary care, organizational interventions, clinician education, nurse case management, psychosomatic medicine, guideline implementation, primary-secondary care integration, cost-effectiveness, depression treatment
- MeSH terms
- Clinical Trials as Topic, Cost-Benefit Analysis, Depression, Depressive Disorder, Humans, Mental Health Services, Outcome and Process Assessment, Health Care, Patient Education as Topic, Primary Health Care
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