The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Immunological Memory: The Role of B Cells in Long-term Protection Against Invasive Bacterial Pathogens
Abstract
Protein-polysaccharide conjugate vaccines that protect against Haemophilus influenzae type b (Hib), serogroup C Neisseria meningitidis, and multiple capsular serotypes of Streptococcus pneumoniae have had a major impact on invasive bacterial disease in childhood when incorporated into routine infant immunization schedules. However, effectiveness data from the United Kingdom suggest that primary infant immunization alone may not be associated with long-term protection. Both immunological priming and antibody persistence are important aspects of long-term protection induced by these vaccines. An improved understanding of the immunobiology of the B-cell response to these vaccines may direct development of immunization strategies that provide sustained protection.
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“it is thought that immune memory may not be sufficient for protection against rapidly invasive bacterial infections that can cause severe disease within hours or days following acquisition of the pathogen42”
From A guide to vaccinology: from basic principles to new developments (2021) · cites this paper as [42]
Citations
Cites
Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells
Bernasconi, N. L., Traggiai, E., & Lanzavecchia, A. (2002) · Science · doi:10.1126/science.1076071 · Cited by 1,304
HUMAN IMMUNITY TO THE MENINGOCOCCUS
Goldschneider, I., Gotschlich, E. C., & Artenstein, M. S. (1969) · The Journal of Experimental Medicine · doi:10.1084/jem.129.6.1307 · Cited by 1,298
Klein, U., Rajewsky, K., & Küppers, R. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.9.1679 · Cited by 1,161
Decline of Childhood Haemophilus influenzae Type b (Hib) Disease in the Hib Vaccine Era
Adams, W. G. (1993) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1993.03500020055031 · Cited by 696
Cutting edge: long-term B cell memory in humans after smallpox vaccination
Crotty, S., Felgner, P., Davies, H., Glidewell, J., Villarreal, L., & Ahmed, R. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.10.4969 · Cited by 695
Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction
Trotter, C. L., Andrews, N. J., Kaczmarski, E. B., Miller, E., & Ramsay, M. E. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16725-1 · Cited by 571
Agematsu, K., Hokibara, S., Nagumo, H., & Komiyama, A. (2000) · Immunology Today · doi:10.1016/s0167-5699(00)01605-4 · Cited by 411
Eskola, J., Käyhty, H. M., Takala, A. K., Peltola, H., Rönnberg, P.-R., Kela, E., Pekkanen, E., McVerry, P. H., & Mäkelä, P. H. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011153232004 · Cited by 334
Tangye, S. G., Avery, D. T., Deenick, E. K., & Hodgkin, P. D. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.2.686 · Cited by 300
Generation and maintenance of immunological memory
Gourley, T. S., Wherry, E. J., Masopust, D., & Ahmed, R. (2004) · Seminars in Immunology · doi:10.1016/j.smim.2004.08.013 · Cited by 241
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T regulatory cells and the germinal center
Alexander, C. (2011) · doi:10.17077/etd.cobmkd2k
Blanchard Rohner, G. (2006) · Archive ouverte UNIGE (University of Geneva) · doi:10.13097/archive-ouverte/unige:444
Memory-immuniteit tegen kinkhoest
Hendrikx, L., Veenhoven, R. H., Sanders, E. A. M., Berbers, G. A. M., & Buisman, A. (2008) · Tijdschrift voor kindergeneeskunde · doi:10.1007/bf03078169
Development of a flagellin-based multivalent vaccine against Pseudomonas aeruginosa
Weimer, E. T. (2009) · WakeSpace Scholarship (Wake Forest University)
Maintaining protection against invasive bacteria with protein- polysaccharide conjugate vaccines
Cohn, M. L., Libero, G. D., Gascoigne, N. R. J., Hoefer, T., Jameson, S. C., Luescher, I. F., Mallaun, M., & Mescher, M. F. (2009)
Novel Complement Blocking Antibodies Against Serogroup B N. meningitidis: A Dissertation
Ray, T. D. (2010) · eScholarship@UMassChan · doi:10.13028/kwp1-3r83
(2006) · Elsevier eBooks · doi:10.1016/b1-416-03007-7/10020-3
Bhagavan, N. V., & Ha, C. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-416687-5.00033-6
Pneumococcal Conjugate Vaccine and Pneumococcal Common Protein Vaccines
Klugman, K. P., Malley, R., & Whitney, C. G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-79058-1.00047-5
Feraoun, G. N. Y. (2022) · theses.fr (ABES) · doi:10.70675/e8e7fd4azd930z4307zad62z2c0404a8d331
Metadata
- Authors
- Kelly, D. F., Pollard, A. J., & Moxon, E. R.
- Affiliations
- University of Oxford (GB)
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2005-12-21
- Volume
- 294
- Issue
- 23
- Pages
- 3019
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2119514683
- Cited by
- 113
- References
- 34
- Citations by year
- 2026: 1 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 5 · 2020: 6 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 2 · 2015: 3 · 2014: 5 · 2013: 9 · 2012: 10
- FWCI
- 6.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Keywords
- Haemophilus influenzae type b, Neisseria meningitidis serogroup C, invasive bacterial infection, childhood immunization, long-term vaccine protection, immune priming, antibody persistence, B cell response, immunological memory
- MeSH terms
- Antibodies, Bacterial, Antibody Affinity, B-Lymphocytes, Bacterial Vaccines, Child, Humans, Immunization, Secondary, Immunologic Memory, Infant, Plasma Cells, Polysaccharides, Bacterial, Vaccination, B-Lymphocyte Subsets, Bacterial Capsules, Haemophilus Vaccines, Vaccines, Conjugate, Meningococcal Vaccines
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