The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Live-Born Major Congenital Heart Disease in Denmark: Incidence, Detection Rate, and Termination of Pregnancy Rate From 1996 to 2013
Open accessAbstract
Importance: The occurrence of major congenital heart disease (CHD) is affected by several variables. Determining the development of the true incidence is critical to the establishment of proper treatment of these patients. Objective: To evaluate time trends in incidence, detection rate, and termination of pregnancy (TOP) rate of major CHD in fetuses in Denmark and assess the influence of the introduction of general prenatal screening in 2004. Design, Setting, and Participants: Nationwide, population-based, retrospective observational study in Denmark from 1996 to 2013 that included a consecutive sample of 14 688 live-born children and terminated fetuses diagnosed as having CHD. Patient records on TOP and children with major CHD were reviewed to validate the diagnoses. Major CHD included univentricular heart, transposition of the great arteries, congenitally corrected transposition of the great arteries, truncus arteriosus, interrupted aortic arch, atrioventricular septal defects, double outlet right ventricle, coarctatio of the aorta, Ebstein anomaly, pulmonary atresia with ventricular septal defect, pulmonary atresia with intact ventricular septum, and tetralogy of Fallot. Data were analyzed between January 2017 and March 2018. Main Outcomes and Measures: Temporal changes in incidence, detection rate, and TOP of major CHD. Results: Of 14 688 children and fetuses diagnosed with CHD, 2695 (18.4%; 95% CI, 17.8-19.1) had major CHD. A total of 7131 boys (1304 with major CHD) and 6926 girls (920 with major CHD) were included, with a median age of 11 years (interquartile range, 6-15 years). During the study period, the live-birth incidence of CHD was constant at 1.22% (95% CI, 1.18-1.26), whereas it decreased for major CHD. When including TOP, the incidence of major CHD did not change over time. The detection rate of major CHD increased from 4.5% (95% CI, 1.2-7.8) to 71.0% (95% CI, 63.3-78.7) (P < .001). At the end of the study, all cases of double outlet right ventricle, Ebstein anomaly, congenitally corrected transposition of the great arteries, and pulmonary atresia with ventricular septal defect were detected prenatally, whereas coarctation of the aorta had the lowest detection rate (21.7%; 95% CI, 3.5-40.0). The TOP rate increased from 0.6% (95% CI, -0.6 to 1.9) to 39.1% (95% CI, 30.9-47.4) (P < .001) among all major CHD. For prenatally diagnosed major CHD, 57.8% of cases were terminated and the proportion did not change significantly throughout the study. Diagnoses leading to TOP included all major CHD diagnoses. Conclusions and Relevance: Detection rates of major CHD improved during the study. This has led to increased TOP rates, with a subsequent 39% decrease in the live-birth incidence of major CHD.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It is likely that this policy has become even more effective since then, as the detection rate of congenital heart defects may have increased 6 .”
From ISUOG Practice Guidelines (updated): performance of the routine mid‐trimester fetal ultrasound scan (2022) · cites this paper as [6]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The incidence of congenital heart disease.
Hoffman, J. I. E., & Kaplan, S. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)01886-7 · Cited by 6,099
Detection of Transposition of the Great Arteries in Fetuses Reduces Neonatal Morbidity and Mortality
Bonnet, D., Coltri, A., Butera, G., Fermont, L., Le Bidois, J., Kachaner, J., & Sidi, D. (1999) · Circulation · doi:10.1161/01.cir.99.7.916 · Cited by 760
Improved Surgical Outcome After Fetal Diagnosis of Hypoplastic Left Heart Syndrome
Tworetzky, W., McElhinney, D. B., Reddy, V. M., Brook, M. M., Hanley, F. L., & Silverman, N. H. (2001) · Circulation · doi:10.1161/01.cir.103.9.1269 · Cited by 678
Prospective diagnosis of 1,006 consecutive cases of congenital heart disease in the fetus
Allan, L. D., Sharland, G. K., Milburn, A., Lockhart, S. M., Groves, A. M. M., Anderson, R. H., Cook, A. C., & Nuala, L. K. (1994) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)90391-3 · Cited by 489
Khairy, P., Clair, M., Fernandes, S. M., Blume, E. D., Powell, A. J., Newburger, J. W., Landzberg, M. J., & Mayer, J. E. (2012) · Circulation · doi:10.1161/circulationaha.112.135046 · Cited by 360
Bull, C. (1999) · The Lancet · doi:10.1016/s0140-6736(99)01167-8 · Cited by 355
Garne, E., Stoll, C. G., & Clementi, M. (2001) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.2001.00385.x · Cited by 349
Tegnander, E., Williams, W., Johansen, O. J., Blaas, H. ‐. K., & Eik‐Nes, S. H. (2006) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.2710 · Cited by 315
Stümpflen, I., Stümpflen, A., Wimmer, M., & BERNASCHEK, G. (1996) · The Lancet · doi:10.1016/s0140-6736(96)04069-x · Cited by 292
Wernovsky, G., Mayer, J. E., Jonas, R. A., Hanley, F. L., Blackstone, E. H., Kirklin, J. W., & Castañeda, A. R. (1995) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(95)70391-8 · Cited by 289
Cited by
Sorted by citations
2020 ESC Guidelines for the management of adult congenital heart disease
Baumgartner, H., Backer, J. F. A. D., Babu‐Narayan, S. V., Budts, W., Chessa, M., Diller, G., Lung, B., Kluin, J., Lang, I. M., Meijboom, F. J., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa554 · Cited by 2,473
Self-citationISUOG Practice Guidelines (updated): performance of the routine mid‐trimester fetal ultrasound scan
Salomon, L. J., Alfirevic, Z., Berghella, V., Bilardo, C. M., Chalouhi, G. E., Da Silva Costa, F., Hernandez‐Andrade, E., Malinger, G., Munoz, H., Paladini, D., et al. (2022) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.24888 · Cited by 436
Survival in Children With Congenital Heart Disease: Have We Reached a Peak at 97%?
Mandalenakis, Z., Giang, K. W., Eriksson, P., Liden, H., Synnergren, M., Wåhlander, H., Fedchenko, M., Rosengren, A., & Dellborg, M. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.017704 · Cited by 430
Bakker, M. K., Bergman, J. E. H., Krikov, S. V., Amar, E., Cocchi, G., Cragan, J. D., de Walle, H. E. K., Gatt, M., Groisman, B., Liu, S., et al. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-028139 · Cited by 276
Why are congenital heart defects being missed?
van Nisselrooij, A. E. L., Teunissen, A. K. K., Clur, S. B., Rozendaal, L., Pajkrt, E., Linskens, I. H., Rammeloo, L. A. J., Lith, J. M. M. V., Blom, N. A., & Haak, M. C. (2019) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.20358 · Cited by 162
Maternal Obesity and Diabetes Mellitus as Risk Factors for Congenital Heart Disease in the Offspring
Helle, E., & Priest, J. R. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.011541 · Cited by 151
Peyvandi, S., Baer, R. J., Chambers, C., Norton, M. E., Rajagopal, S. K., Ryckman, K. K., Moon‐Grady, A. J., Jelliffe‐Pawlowski, L. L., & Steurer, M. A. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.015255 · Cited by 91
Chen, J., Huang, S., Zhang, Y., Chang, Q. H., Zhang, Y., Li, D., Qiu, J., Hu, L., Peng, X., Du, Y., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-44930-y · Cited by 80
Risk Factors for Brain Abscess: A Nationwide, Population-Based, Nested Case-Control Study
Bodilsen, J., Dalager‐Pedersen, M., van de Beek, D., Brouwer, M. C., & Nielsen, H. I. (2019) · Clinical Infectious Diseases · doi:10.1093/cid/ciz890 · Cited by 73
Ryd, D., Fricke, K., Bhat, M., Arheden, H., Liuba, P., & Hedström, E. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.3538 · Cited by 60
DeVore, G. R., Haxel, C. S., Satou, G. M., Sklansky, M., Pelka, M., Jone, P., & Cuneo, B. F. (2020) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.21989 · Cited by 54
Diagnostic Accuracy of Machine Learning Models to Identify Congenital Heart Disease: A Meta-Analysis
Hoodbhoy, Z. A., Jiwani, U., Sattar, S., Salam, R. A., Hasan, B. S., & Das, J. K. (2021) · Frontiers in Artificial Intelligence · doi:10.3389/frai.2021.708365 · Cited by 53
Artificial Intelligence in Pediatric Cardiology: A Scoping Review
Sethi, Y., Patel, N., Kaka, N., Desai, A., Kaiwan, O., Sheth, M., Sharma, R., Huang, H. Y. R., Chopra, H., Khandaker, M. U., et al. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11237072 · Cited by 55
Miremberg, H., Gindes, L., Schreiber, L., Sternfeld, A. R., Bar, J., & Kovo, M. (2019) · Prenatal Diagnosis · doi:10.1002/pd.5515 · Cited by 49
Stayner, L. T., Jensen, A. S., Schullehner, J., Coffman, V. R., Trabjerg, B. B., Olsen, J., Hansen, B., Pedersen, M., Pedersen, C. B., & Sigsgaard, T. (2022) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2021.100286 · Cited by 48
Hedermann, G., Hedley, P. L., Thagaard, I. N., Krebs, L., Ekelund, C. K., Sørensen, T. I. A., & Christiansen, M. (2021) · PLOS ONE · doi:10.1371/journal.pone.0252343 · Cited by 48
Giang, K. W., Mandalenakis, Z., Fedchenko, M., Eriksson, P., Rosengren, A., Norman, M., Hanséus, K., & Dellborg, M. (2022) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwac227 · Cited by 50
Hautala, J., Gissler, M., Ritvanen, A., Tekay, A., Pitkänen-Argillander, O. M., Stefanović, V., Sarkola, T., Helle, E., Pihkala, J. I., Pätilä, T., et al. (2018) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.15589 · Cited by 39
Perez, M., Bucholz, E. M., Asimacopoulos, E. P., Ferraro, A. M., Salem, S. M., Schauer, J. S., Holleman, C. M., Sekhavat, S., Tworetzky, W., Powell, A. J., et al. (2022) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.24863 · Cited by 39
Cohort Profile: The Copenhagen Baby Heart Study (CBHS)
Vøgg, R. O. B., Basit, S., Raja, A. A., Sillesen, A., Pihl, C., Vejlstrup, N. G., Jonsen, E. H., Larsen, O. W., Zingenberg, H., Boyd, H. A., et al. (2021) · International Journal of Epidemiology · doi:10.1093/ije/dyab147 · Cited by 39
Self-citationZhang, X., Sun, Y., Zhu, J., Zhu, Y., & Qiu, L. (2020) · BMC Pediatrics · doi:10.1186/s12887-020-02313-4 · Cited by 37
Kaur, A., Hornberger, L. K., Fruitman, D. S., Ngwezi, D. P., & Eckersley, L. (2022) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.26030 · Cited by 36
Combs, C. A., Hameed, A. B., Friedman, A. M., & Hoskins, I. A. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.02.040 · Cited by 36
Alkhodari, M., Hadjileontiadis, L. J., & Khandoker, A. H. (2024) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2024.3357506 · Cited by 33
Fetal Echocardiographic Dimension Indices: Important Predictors of Postnatal Coarctation
Fricke, K., Liuba, P., & Weismann, C. G. (2020) · Pediatric Cardiology · doi:10.1007/s00246-020-02509-6 · Cited by 33
Lessons from exome sequencing in prenatally diagnosed heart defects: A basis for prenatal testing
Westphal, D. S., Leszinski, G. S., Rieger‐Fackeldey, E., Graf, E., Weirich, G., Meitinger, T., Ostermayer, E., Oberhoffer, R., & Wagner, M. (2019) · Clinical Genetics · doi:10.1111/cge.13536 · Cited by 33
Cheung, P., Hajihosseini, M., Dinu, I. A., Switzer, H. N., Joffe, A. R., Bond, G. Y., & Robertson, C. M. T. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2020.616659 · Cited by 33
Tomek, V., Jičínská, H., Pavlíček, J., Kovanda, J., Jehlička, P., Klásková, E., Mrázek, J., Čutka, D., Smetanová, D., Brestak, M., et al. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.34069 · Cited by 32
Congenital heart defects in children born after assisted reproductive technology: a CoNARTaS study
Sargisian, N., Petzold, M., Furenäs, E., Gissler, M., Spangmose, A. L., Malchau, S. S., Opdahl, S., Pinborg, A. B., Henningsen, A.-K. A., Westvik‐Johari, K., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae572 · Cited by 28
Holst, L. M., Kronborg, J. B., Jepsen, J. R. M., Christensen, J. Ø., Vejlstrup, N. G., Juul, K., Bjerre, J. V., Bilenberg, N., & Ravn, H. B. (2020) · Cardiology in the Young · doi:10.1017/s1047951119003184 · Cited by 24
Self-citationAI supported fetal echocardiography with quality assessment
Taksøe‐Vester, C., Mikolaj, K. W., Bashir, Z., Christensen, A. N., Petersen, O. B., Sundberg, K., Feragen, A., Svendsen, M. B. S., Nielsen, M., & Tolsgaard, M. G. (2024) · Scientific Reports · doi:10.1038/s41598-024-56476-6 · Cited by 29
Self-citationNeonatal management of prenatally suspected coarctation of the aorta
Hede, S. V., DeVore, G. R., Satou, G. M., & Sklansky, M. (2020) · Prenatal Diagnosis · doi:10.1002/pd.5696 · Cited by 24
de Sousa, M. T., Hecher, K., Kording, F., Yamamura, J., Lenz, A., Adam, G., Bannas, P., & Schoennagel, B. P. (2020) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.13957 · Cited by 22
Cardinal, M.-P., Gagnon, M.-H., Têtu, C., Beauchamp, F.-O., Roy, L.-O., Noël, C., Vaujois, L., Cavallé-Garrido, T., Bigras, J., Roy‐Lacroix, M., et al. (2022) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.121.013796 · Cited by 23
Prenatal diagnosis of congenital heart defects and voluntary termination of pregnancy
Montaguti, E., Balducci, A., Perolo, A., Livi, A., Contro, E., Casadio, P., Donti, A., Angeli, E., Gargiulo, G., & Pilu, G. (2020) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2020.100207 · Cited by 24
The accuracy of prenatal diagnosis of major congenital heart disease is increasing
Lytzen, R. M. T., Vejlstrup, N. G., Bjerre, J. V., Petersen, O. B., Leenskjold, S., Dodd, J. K., Jørgensen, F. S., & Søndergaard, L. (2019) · Journal of Obstetrics and Gynaecology · doi:10.1080/01443615.2019.1621814 · Cited by 22
Self-citationVijayaraghavan, A., Sudhakar, A., Sundaram, K. R., Kumar, R., & Vaidyanathan, B. (2019) · Cardiology in the Young · doi:10.1017/s104795111900252x · Cited by 22
DeVore, G. R., Satou, G. M., Afshar, Y., Harake, D. E., & Sklansky, M. (2021) · Journal of Ultrasound in Medicine · doi:10.1002/jum.15639 · Cited by 20
Major heart defects: the diagnostic evaluations of first-year-olds
Pavlíček, J., Klásková, E., Kaprálová, S., Palátová, A., Piegzová, A., Špaček, R., & Gruszka, T. (2021) · BMC Pediatrics · doi:10.1186/s12887-021-02997-2 · Cited by 20
Time Trends in Simple Congenital Heart Disease Over 39 Years: A Danish Nationwide Study
El-Chouli, M. H., Mohr, G. H., Bang, C. N., Malmborg, M. W., Ahlehoff, O., Torp-Pedersen, C. T., Gerds, T. A., Idorn, L., Raunsø, J., & Gislason, G. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.020375 · Cited by 20
Impact of Socioeconomic Status and Residence Distance on Infant Heart Disease Outcomes in Canada
Olugbuyi, O., Smith, C., Kaul, P., Dover, D. C., Mackie, A. S., Islam, S., Eckersley, L., & Hornberger, L. K. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.122.026627 · Cited by 19
Birth prevalence of congenital heart defects in Western Australia, 1990–2016
Hansen, M., Greenop, K. R., Yim, D., Ramsay, J., Thomas, Y., & Baynam, G. S. (2021) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.15592 · Cited by 16
Current outcomes and future trends in paediatric and congenital cardiac surgery: a narrative review
Király, L. (2021) · Pediatric Medicine · doi:10.21037/pm-21-47 · Cited by 19
Yan, H., Zhai, B., Feng, R., Wang, P., Zhang, Y., Wang, Y., Hou, Y., & Zhou, Y. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.828300 · Cited by 21
Detection of severe congenital heart defects in live‐born infants in Norway 2017–2020
Wik, G., Jortveit, J., Sitras, V., Perminow, K. V., Pripp, A. H., Døhlen, G., Rønnestad, A. E., & Holmström, H. (2023) · Acta Paediatrica · doi:10.1111/apa.16953 · Cited by 16
Trends in the Prenatal Detection of Major Congenital Heart Disease in Alberta From 2008–2018
Kaur, A., Hornberger, L. K., Fruitman, D. S., Ngwezi, D. P., Chandra, S., & Eckersley, L. (2022) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2022.03.020 · Cited by 16
Lee, J. S., Jung, J., Choi, J.-U., Seo, W., & Shin, H. J. (2022) · Yonsei Medical Journal · doi:10.3349/ymj.2022.0111 · Cited by 16
Screening for Critical Congenital Heart Defects in Sweden
Lannering, K., Kazamia, K., Bergman, G., Östman‐Smith, I., Liuba, P., Dahlqvist, J. A., Elfvin, A., & Mellander, M. (2023) · PEDIATRICS · doi:10.1542/peds.2023-061949 · Cited by 15
Impact of prenatally diagnosed congenital heart defects on outcomes and management
Wong, J., Kohari, K. S., Bahtiyar, M. O., & Copel, J. A. (2022) · Journal of Clinical Ultrasound · doi:10.1002/jcu.23219 · Cited by 15
Prenatal detection rate of major congenital heart defects in Copenhagen from 2015 to 2018
Vedel, C., Tabor, A., Jørgensen, F. S., Rode, L., Sundberg, K., Vejlstrup, N. G., Zingenberg, H., & Ekelund, C. K. (2020) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.22167 · Cited by 14
Self-citationEvans, W. N., Acherman, R. J., & Restrepo, H. (2021) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2021.2004115 · Cited by 13
Weichert, J., & Weichert, A. (2021) · Echocardiography · doi:10.1111/echo.15037 · Cited by 13
Matsui, H., Hirata, Y., Inuzuka, R., Hayashi, T., Nagamine, H., Ueda, T., & Nakayama, T. (2021) · Journal of Cardiology · doi:10.1016/j.jjcc.2021.08.013 · Cited by 11
Chih, W.-L., Tung, Y.-H., Lussier, E. C., Sung, C.-Y., Huang, Y., Hung, W., Hsu, K.-H., Chang, C., Chang, T. Y., & Chen, M. (2022) · Pediatrics & Neonatology · doi:10.1016/j.pedneo.2022.07.015 · Cited by 11
Long-term Mortality and Risk of Epilepsy in Children and Young Adults With Brain Abscess
Bodilsen, J., Dalager‐Pedersen, M., & Nielsen, H. V. (2020) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0000000000002736 · Cited by 11
Hjort‐Pedersen, K., Olesen, A. W., Garne, E., & Sperling, L. (2023) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.14582 · Cited by 11
Liu, L., Wang, H., Cui, C., Li, Y., Liu, Y., Wang, Y., Fan, T., & Peng, B. (2019) · Medicine · doi:10.1097/md.0000000000017492 · Cited by 11
Sanapo, L., Donofrio, M. T., Ahmadzia, H. K., Gimovsky, A. C., & Mohamed, M. A. (2020) · Journal of Perinatology · doi:10.1038/s41372-020-00795-9 · Cited by 11
Guía ESC 2020 para el tratamiento de las cardiopatías congénitas del adulto
Baumgartner, H., Backer, J. F. A. D., Babu‐Narayan, S. V., Budts, W., Chessa, M., Diller, G., Iung, B., Kluin, J., Lang, I. M., Meijboom, F. J., et al. (2021) · Revista Española de Cardiología · doi:10.1016/j.recesp.2020.10.023 · Cited by 13
Self-citationAortic Coarctation: The Fetal Cardiologist’s Achilles Heel
Hornberger, L. K., & Eckersley, L. (2021) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.121.012877 · Cited by 11
Vepa, S., Alavi, M., Wu, W., Schmittdiel, J. A., Herrinton, L. J., & Desai, K. H. (2024) · Prenatal Diagnosis · doi:10.1002/pd.6544 · Cited by 9
Phillips, A. A., Punn, R., Algaze, C. A., Blumenfeld, Y. J., Chock, V. Y., Kwiatkowski, D. M., Quirin, A., Tacy, T. A., Thorson, K., & Maskatia, S. A. (2024) · Fetal Diagnosis and Therapy · doi:10.1159/000538550 · Cited by 9
Gröning, M., Smerup, M., Nielsen, D. G., Nissen, H., Munk, K., Mortensen, U. M., Andersen, H., Engholm, M., Bjerre, J. V., Vejlstrup, N. G., et al. (2023) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezad007 · Cited by 9
Self-citationExtra‐cardiac diagnoses and postnatal outcomes of fetal tetralogy of fallot
Sharma, R., Niederhoffer, K. Y., Caluseriu, O., Cooke, C. M., Hornberger, L. K., He, R., Eckersley, L., Lin, L. Q., Rushfeldt, M., & McBrien, A. (2022) · Prenatal Diagnosis · doi:10.1002/pd.6102 · Cited by 9
Kim, S. T., Song, J., Huh, J., Kang, I., Yang, J., Jun, T.-G., Oh, S., Choi, S., & Roh, C. (2019) · Journal of Korean Medical Science · doi:10.3346/jkms.2019.34.e170 · Cited by 9
Kristensen, R., Omann, C., Gaynor, J. W., Rode, L., Ekelund, C. K., & Hjortdal, V. E. (2023) · Frontiers in Pediatrics · doi:10.3389/fped.2023.1104179 · Cited by 9
Ethical issues after pre-natal diagnosis
Corno, A. F. (2021) · Translational Pediatrics · doi:10.21037/tp-20-141 · Cited by 8
Clinical implementation of first trimester screening for congenital heart defects
Helmbæk, M. E., Sundberg, K., Jørgensen, D. S., Petersen, O. B., Tolsgaard, M. G., Vejlstrup, N. G., Harmsen, L., Kruse, C. D., Steensberg, J. N., Vedel, C., et al. (2024) · Prenatal Diagnosis · doi:10.1002/pd.6584 · Cited by 8
Self-citationNationwide Birth Prevalence of Crucial Congenital Heart Defects From 2014 to 2018 in Korea
Ha, K. S., Park, C. M., Lee, J. H., Shin, J. H., Choi, E. K., Choi, M., Kim, J., Shin, H. J., Choi, B. M., & Kim, S. (2024) · Korean Circulation Journal · doi:10.4070/kcj.2024.0105 · Cited by 8
Adverse Obstetric Outcomes in Pregnancies With Major Fetal Congenital Heart Defects
Hedermann, G., Hedley, P. L., Gadsbøll, K., Thagaard, I. N., Krebs, L., Karlsen, M. A., Vedel, C., Rode, L., Christiansen, M., & Ekelund, C. K. (2024) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2024.5073 · Cited by 8
Cardiac Implantable Electronic Device–Related Infection Due to Granulicatella adiacens
Sendi, P., Wustmann, K., Büchi, A. E., Noti, F., Klaeser, B., Sonderegger, B., der Maur, C. A., Mercier, T., Schwerzmann, M., & Ruppen, C. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofz130 · Cited by 8
Natterer, J., Schneider, J., Sekarski, N., Rathke, V., Adams, M., Latal, B., Borradori-Tolsa, C., Bouhabib, M., Kradolfer, K. F., Glöckler, M., et al. (2022) · Swiss Medical Weekly · doi:10.4414/smw.2022.w30217 · Cited by 8
Universal Fetal Echocardiography for Pregestational Diabetes Mellitus
Savitsky, L. M., Hamilton, C., Sterrett, M. E., Olerich, K. L. W., Ma, K., & Albright, C. M. (2024) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000005538 · Cited by 9
Type of infertility and prevalence of congenital malformations
Basso, O., Shapiro, G. D., Gagnon, R. J., Tamblyn, R. M., & Platt, R. W. (2023) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.13012 · Cited by 7
Mutation burden in patients with small unrepaired atrial septal defects
Nielsen, A. K. M., Nyboe, C., Ovesen, A. S. L., Udholm, S., Larsen, M. M., Hjortdal, V. E., & Larsen, L. A. (2021) · International Journal of Cardiology Congenital Heart Disease · doi:10.1016/j.ijcchd.2021.100164 · Cited by 7
Fricke, K., Ryd, D., Weismann, C. G., Hanséus, K., Hedström, E., & Liuba, P. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1285391 · Cited by 7
A population-based study of neonatal air transport in the Arctic region of Norway from 1994 to 2023
Trulsen, L. N., Hansen, L. G., Songstad, N. T., Lang, A. M., & Klingenberg, C. (2025) · Frontiers in Pediatrics · doi:10.3389/fped.2025.1594729 · Cited by 6
Severe Congenital Heart Defects and Cerebral Palsy
Garne, E., Goldsmith, S. C., Barišić, I., Braz, P., Đaković, I., Gibson, C. S., Hansen, M., Hoei‐Hansen, C. E., Hollung, S. J., Klungsøyr, K., et al. (2023) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2023.113617 · Cited by 6
Hedermann, G., Hedley, P. L., Gadsbøll, K., Thagaard, I. N., Krebs, L., Hagen, C. M., Sørensen, T. I. A., Christiansen, M., & Ekelund, C. K. (2024) · International Journal of Obesity · doi:10.1038/s41366-024-01531-5 · Cited by 13
Lim, C. W., Jensen, A. S., Marstein, C. M., Bække, P. S., Thuraiaiyah, J., Lytzen, R. M. T., Jøns, C., Schmidt, M. R., Søndergaard, L., & Jørgensen, T. H. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.124.035115 · Cited by 6
Self-citationMasood, S. N., Baqai, S. M., Naheed, F., Masood, Y., Sikandar, R., Chaudhri, R., Yasmin, H., & Korejo, R. (2021) · Journal of Diabetology · doi:10.4103/jod.jod_88_20 · Cited by 6
Association between parental decisions regarding abortion and severity of fetal heart disease
Nakao, M., Kuwabara, M., Saito, M., Horiuchi, C., Morisaki, H., Kishiki, K., Hamamichi, Y., Orui, I., Ono, R., Suzuki, R., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-66027-8 · Cited by 6
Prenatal detection and outcome of major heart defects in a country with universal screening
Vedel, C., Steensberg, J. N., Petersen, O. B., Andersen, H., Barbosa, M., Christiansen, M., Gjørup, V., Jensen, A., Munk, K., Nyborg, K. M., et al. (2025) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.70107 · Cited by 5
Self-citationvan der Have, O., Tran‐Lundmark, K., Wåhlander, H., Kaskinen, A. K., Møller, T., Juul, K., Jahnukainen, T., Weinreich, I. D., Sarkola, T., Nilsson, J., et al. (2025) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2025.05.020 · Cited by 5
Wiezell, E., Guðnason, J. F., Synnergren, M. J., & Sunnegårdh, J. T. (2020) · Acta Paediatrica · doi:10.1111/apa.15732 · Cited by 5
Diagnosis of severe congenital heart defects in Norway 2016
Jortveit, J., Wik, G., Ødegaard, J. S., Sitras, V., Perminow, K. V., & Holmström, H. (2019) · Tidsskrift for Den norske legeforening · doi:10.4045/tidsskr.18.0606 · Cited by 5
Jiang, Y. (2024) · BMC Medical Imaging · doi:10.1186/s12880-024-01235-2 · Cited by 4
Stancioi-Cismaru, A. F., Dinu, M., Carp-Velişcu, A., Capitanescu, R. G., Pana, R. C., Sîrbu, O. C., Tanase, F., Dita, F.-A., Popa, M. A., Robu, M. R., et al. (2024) · Diagnostics · doi:10.3390/diagnostics14111185 · Cited by 3
Чазова, И. Е., Горбачевский, С. В., Martynyuk, T. V., Shmalts, A. A., Солтановна, В. З., Baryshnikova, I. Y., Glushko, L. A., Владимирович, Г. В., Азизов, В. А., Veselova, T. N., et al. (2022) · Eurasian heart journal · doi:10.38109/2225-1685-2022-1-6-70 · Cited by 5
Cost-utility analysis of prenatal diagnosis of congenital cardiac diseases using deep learning
Ginsberg, G. M., Drukker, L., Pollak, U., & Brezis, M. (2024) · Cost Effectiveness and Resource Allocation · doi:10.1186/s12962-024-00550-3 · Cited by 5
Aoyama, R., Komatsu, M., Harada, N., Komatsu, R., Sakai, A., Takeda, K., Teraya, N., Asada, K., Kaneko, S., Iwamoto, K., et al. (2024) · Bioengineering · doi:10.3390/bioengineering11121256 · Cited by 4
Lin, Y., Huang, Y., Lin, C., Wu, V. C., Kao, Y., Chiang, H., & Chu, P. (2023) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2408225 · Cited by 4
Prevalence and detection rate of major congenital heart disease in twin pregnancies in Denmark
Bouazzi, M., Jørgensen, D. S., Andersen, H., Krusenstjerna-Hafstrøm, T., Ekelund, C. K., Jensen, A., Sandager, P., Sperling, L., Steensberg, J. N., Sundberg, K., et al. (2023) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.26249 · Cited by 3
Self-citationRaaby, L., Lou, S., Ivarsen, R. R. L., Sørensen, J. L., Larsen, O. H., & Vogel, I. (2024) · Prenatal Diagnosis · doi:10.1002/pd.6526 · Cited by 3
Gelaw, T. T., & Alebachew, B. Z. (2024) · Progress in Pediatric Cardiology · doi:10.1016/j.ppedcard.2024.101776 · Cited by 3
Henningsen, M. B., Bohnstedt, C., Vestergaard, T. R., Smerup, M., Madsen, P. V., & Stensballe, L. G. (2025) · Scientific Reports · doi:10.1038/s41598-025-15769-0 · Cited by 3
Morimoto, Y., Go, K., Yamamoto, H., Fukasawa, Y., Nakai, M., Morihana, E., Yasuda, K., Nishikawa, H., Ohashi, N., Takahashi, Y., et al. (2021) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2021.10.005 · Cited by 3
Schneider, K., Bousi, D., & Stressig, R. (2022) · Cardiology in the Young · doi:10.1017/s104795112200213x · Cited by 3
Evaluation of Infective Endocarditis in Children: A 19-Year Retrospective Study in Taiwan
Chien, S., Tseng, Y., Huang, Y.-H., Liu, H.-Y., Wu, Y., Chang, L., Yang, Y., & Lin, Y.-J. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12062298 · Cited by 3
Steffensen, E. H., Pedersen, L. H., Lou, S., Vogel, I., & The Danish Cytogenetic Central Registry Study Group (2023) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.14573 · Cited by 3
Metadata
- Authors
- Lytzen, R., Vejlstrup, N., Bjerre, J., Petersen, O. B., Leenskjold, S., Dodd, J. K., Jørgensen, F. S., & Søndergaard, L.
- Affiliations
- Rigshospitalet (DK)
- Aarhus University Hospital (DK)
- Aalborg University Hospital (DK)
- Hvidovre Hospital (DK)
- Corresponding author
- Lytzen, Rebekka
- Venue
- JAMA Cardiology
- Publisher
- American Medical Association (AMA)
- Published
- 2018-09-01
- Volume
- 3
- Issue
- 9
- Pages
- 829
- ISSN
- 2380-6583 (ISSN-L)
- PMC
- PMC6233653
- OpenAlex
- W2884472067
- Cited by
- 169
- References
- 35
- Citations by year
- 2026: 16 · 2025: 26 · 2024: 31 · 2023: 22 · 2022: 18 · 2021: 24 · 2020: 17 · 2019: 14 · 2018: 1
- FWCI
- 10.91
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- JAMA Cardiology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- VBN Forskningsportal (Aalborg Universitet) (submittedVersion, other-oa)
- Scopus (Elsevier) (submittedVersion, other-oa)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Funders
- Rigshospitalet
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
- Health Sciences › Medicine › Surgery › Congenital Anomalies and Fetal Surgery
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Screening and Diagnostics
- Keywords
- major congenital heart disease, incidence, prenatal screening, abortion, fetal diagnosis, detection rate, temporal trends, single ventricle, transposition of the great arteries, interrupted aortic arch, atrioventricular septal defect, tetralogy of Fallot, Denmark, live birth, fetal death, sex differences, prenatal diagnosis of congenital heart disease
- MeSH terms
- Abortion, Induced, Adolescent, Child, Denmark, Female, Heart Defects, Congenital, Humans, Pregnancy, Prenatal Diagnosis, Retrospective Studies, Incidence, Early Diagnosis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
