Icosapent Ethyl Supplementation and Cardiovascular Prevention—Implications of Evolving Data
Abstract
This Viewpoint discusses the findings of the Reduction of Cardiovascular Events With Icosapent Ethyl Intervention Trial regarding the use of icosapent ethyl in moderate- to high-risk patients with fasting triglyceride levels greater than 135 mg/dL.
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JELIS was challenged for its selection of patients with a relatively high background of fish consumption, and REDUCE-IT was revisited for the use of mineral oil as a comparator.
“Moreover, JELIS was often challenged for its selection of patients with a relatively high background of fish consumption, 26 and REDUCE‐IT was revisited for the use of mineral oil as a comparator, 27 , 28 , 29 respectively.”
From Association Between Omega-3 Fatty Acid Intake and Dyslipidemia: A Continuous Dose-Response Meta-Analysis of Randomized Controlled Trials (2023) · cites this paper as [28]
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References 9 · Cited by 2
- Authors
- Wilkins, J. T., & Lloyd-Jones, D. M.
- Affiliations
- Northwestern University (US)
- Department of Medicine (Cardiology), Northwestern University Feinberg School of Medicine, Chicago, Illinois
- ORCID
- Wilkins, John T.
- Venue
- JAMA Cardiology
- Publisher
- American Medical Association (AMA)
- Published
- 2022-12-01
- Volume
- 7
- Issue
- 12
- Pages
- 1185
- ISSN
- 2380-6583 (ISSN-L)
- OpenAlex
- W4307337684
- Cited by
- 2
- References
- 9
- Citations by year
- 2023: 2
- FWCI
- 0.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Keywords
- icosapent ethyl, omega-3 fatty acids, cardiovascular disease prevention, hypertriglyceridemia, fasting triglycerides, cardiovascular risk
- MeSH terms
- Cardiovascular Diseases, Humans, Eicosapentaenoic Acid, Hypertriglyceridemia, Dietary Supplements
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