Cited by 386Posttraumatic Stress Disorder ResearchStress Responses and CortisolTraumatic Brain Injury Research

The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.

Assessment of Plasma C-Reactive Protein as a Biomarker of Posttraumatic Stress Disorder Risk

Open access

Eraly, Satish A., Nievergelt, Caroline M., Maihofer, Adam X., Barkauskas, Donald A., Biswas, Nilima, Agorastos, Agorastos, O’Connor, Daniel T., Baker, Dewleen G.·2014·JAMA Psychiatry

DOI 10.1001/jamapsychiatry.2013.4374PMC PMC4032578

Open this paper in CoChat — free account

Abstract

IMPORTANCE: Posttraumatic stress disorder (PTSD) has been associated in cross-sectional studies with peripheral inflammation. It is not known whether this observed association is the result of PTSD predisposing to inflammation (as sometimes postulated) or to inflammation predisposing to PTSD. OBJECTIVE: To determine whether plasma concentration of the inflammatory marker C-reactive protein (CRP) helps predict PTSD symptoms. DESIGN, SETTING, AND PARTICIPANTS: The Marine Resiliency Study, a prospective study of approximately 2600 war zone-deployed Marines, evaluated PTSD symptoms and various physiological and psychological parameters before deployment and at approximately 3 and 6 months following a 7-month deployment. Participants were recruited from 4 all-male infantry battalions imminently deploying to a war zone. Participation was requested of 2978 individuals; 2610 people (87.6%) consented and 2555 (85.8%) were included in the present analysis. Postdeployment data on combat-related trauma were included for 2208 participants (86.4% of the 2555 included) and on PTSD symptoms at 3 and 6 months after deployment for 1861 (72.8%) and 1617 (63.3%) participants, respectively. MAIN OUTCOMES AND MEASURES: Severity of PTSD symptoms 3 months after deployment assessed by the Clinician-Administered PTSD Scale (CAPS). RESULTS: We determined the effects of baseline plasma CRP concentration on postdeployment CAPS using zero-inflated negative binomial regression (ZINBR), a procedure designed for distributions, such as CAPS in this study, that have an excess of zeroes in addition to being positively skewed. Adjusting for the baseline CAPS score, trauma exposure, and other relevant covariates, we found baseline plasma CRP concentration to be a highly significant overall predictor of postdeployment CAPS scores (P = .002): each 10-fold increment in CRP concentration was associated with an odds ratio of nonzero outcome (presence vs absence of any PTSD symptoms) of 1.51 (95% CI, 1.15-1.97; P = .003) and a fold increase in outcome with a nonzero value (extent of symptoms when present) of 1.06 (95% CI, 0.99-1.14; P = .09). CONCLUSIONS: AND RELEVANCE A marker of peripheral inflammation, plasma CRP may be prospectively associated with PTSD symptom emergence, suggesting that inflammation may predispose to PTSD.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1001/jamapsychiatry.2013.4374

Cites

82 of 82 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The development of a Clinician-Administered PTSD Scale
Blake, D. D., Weathers, F. W., Nagy, L. M., Kaloupek, D. G., Gusman, F. D., Charney, D. S., & Keane, T. M. (1995) · Journal of Traumatic Stress · doi:10.1002/jts.2490080106 · Cited by 5,024
Inflammation and insulin resistance
Shoelson, S. E. (2006) · Journal of Clinical Investigation · doi:10.1172/jci29069 · Cited by 4,769
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
Miller, A. H., Maletic, V., & Raison, C. L. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.11.029 · Cited by 3,848
The Metabolic Syndrome and Cardiovascular Risk
Mottillo, S., Filion, K. B., Genest, J., Joseph, L., Pilote, L., Poirier, P., Rinfret, S., Schiffrin, E. L., & Eisenberg, M. J. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.05.034 · Cited by 3,009
Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis.
Howren, M. B., Lamkin, D. M., & Suls, J. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181907c1b · Cited by 2,766
Macrophages, inflammation, and insulin resistance
Olefsky, J. M., & Glass, C. K. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135846 · Cited by 2,733
Obesity, Inflammation, and Insulin Resistance
Shoelson, S. E., Herrero, L., & Naaz, A. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.03.059 · Cited by 1,806
Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma
Gilbertson, M. W., Shenton, M. E., Ciszewski, A., Kasai, K., Lasko, N. B., Orr, S. P., & Pitman, R. K. (2002) · Nature Neuroscience · doi:10.1038/nn958 · Cited by 1,635
Cytokine-Associated Emotional and Cognitive Disturbances in Humans
Reichenberg, A., Yirmiya, R., Schuld, A., Kraus, T., Haack, M., Morag, A., & Pollmächer, T. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.5.445 · Cited by 1,365
Post-Traumatic Stress Disorder
Yehuda, R. (2002) · New England Journal of Medicine · doi:10.1056/nejmra012941 · Cited by 1,134

Flagged first, then by citations

Show all 81 references

Research works printed but not linked: 1

[8]Tucker P Jeon-Slaughter H Pfefferbaum B Khan Q Davis NJ Emotional and biological stress measures in Katrina survivors relocated to Oklahoma Am J Disaster Med 2010 5 2 113 125 20496644

Sorted by citations

Items 301–385 of 385

The complex neurobiology of resilient functioning after child maltreatmentPreprint
Ioannidis, K., Askelund, A. D., Kievit, R., & van Harmelen, A. (2016) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/3vfqb · Cited by 3
Mental health symptoms are not correlated with peripheral inflammatory biomarkers concentrations in COVID-19-ARDS survivors
Chean, D., Benarroch, S., Pochard, F., Kentish‐Barnes, N., Azoulay, É., the Famirea study group, Resche‐Rigon, M., Mégarbane, B., Reuter, D., Labbé, V., et al. (2022) · Intensive Care Medicine · doi:10.1007/s00134-022-06936-2 · Cited by 2
WITHDRAWN: Pro-inflammatory markers are related to cortical network connectivity in women exposed to interpersonal trauma with PTSD
Yetter, M. A., Fitzgerald, T. R., Philippi, C. L., & Bruce, S. E. (2024) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.114942 · Cited by 2
Retracted
Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohortsPreprint
Katrinli, Ş., Wani, A. H., Maihofer, A. X., Ratanatharathorn, A. D., Daskalakis, N. P., Montalvo‐Ortiz, J. L., Núñez-Ríos, D. L., Zannas, A. S., Zhao, X., Aiello, A. E., et al. (2024) · medRxiv · doi:10.1101/2024.07.15.24310422 · Cited by 2
Self-citation
Staging model of PTSD: a strategy for the implementation of precision medicine in military settings
McFARLANE, A. C. (2023) · BMJ Military Health · doi:10.1136/military-2023-002352 · Cited by 1
Psycho-Somatic Evolution of Patients with Multiple Traumatic Injuries
Anghele, M., Marina, V., Moscu, C.-A., Anghele, A.-D., & Dragomir, L. (2024) · Clinics and Practice · doi:10.3390/clinpract14060189 · Cited by 1
Application of vagal nerve stimulation to post-traumatic stress disorder
Wittbrodt, M. T., Gurel, N. Z., Inan, O. T., Mehta, P. K., & Bremner, J. D. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-816996-4.00011-3 · Cited by 1
Transauricular vagus nerve stimulation in preventing post-traumatic stress disorder in emergency trauma surgery patients in China: a study protocol for a multicenter, double-blind, randomised, controlled trial
Zhang, J., Shen, Q.-H., Lin, X., Liu, T., Yu, L., Yu, Y., Liang, J., Xin, Y., & Chen, G. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-093467 · Cited by 1
Advancements in the Diagnosis and Treatment of War-Related Post-traumatic Stress Disorder: A Narrative Review
Shi, L., Leng, W. T., Song, P., Sun, Q., Ren, F., Tian, Y., & Wang, Y. (2025) · Iranian Journal of Psychiatry and Behavioral Sciences · doi:10.5812/ijpbs-162324 · Cited by 1
Peripheral immune system activity in young psychiatry patients
Seizer, L., Löchner, J., & Renner, T. J. (2025) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2025.101143 · Cited by 1
Development and validation of machine learning models to predict PTSD at multiple time points in hospitalized trauma patients
Chu, X., Dai, X., Jiang, X., Liu, S., Chen, W., Zhao, S., Zhou, Y., & Shi, X. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.121096 · Cited by 1
Identification of Fibrinogen C Domain-Containing protein 1 (FIBCD1) as a novel target for treatment of Post-Traumatic stress disorder (PTSD) and discovery of a novel FIBCD1 inhibitor
Ma, S., Wang, Z., Zhang, F., & Zhang, H. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.106775 · Cited by 1
„Old Friends“, Immunregulation und Stressresilienz
Langgartner, D., Lowry, C. A., & Reber, S. O. (2020) · Nervenheilkunde · doi:10.1055/a-1037-0710 · Cited by 1
Post-traumatic stress in older, community-dwelling adults with hypertension during the COVID-19 pandemic: An investigation of pre-pandemic sociodemographic, health, and vascular and inflammatory biomarker predictors
Troyer, E. A., Kohn, J. N., Castillo, M. F. R., Lobo, J. D., Sanchez, Y. R., Ang, G., Cirilo, A., Leal, J. A., Pruitt, C., Walker, A., et al. (2023) · Journal of Health Psychology · doi:10.1177/13591053231213305 · Cited by 1
Inflammation as the Common Pathophysiology Linking Stress, Mental Illness, Autoimmunity and Chronic Disease: Implications for Public Health Policy
Kinderlehrer, D. A. (2024) · Journal of Biomedical Research & Environmental Sciences · doi:10.37871/jbres1889 · Cited by 2
Regeneration at the interface of mental and physical health after trauma
Haffner‐Luntzer, M., Reber, S. O., Huber-Lang, M. S., & Ignatius, A. A. (2024) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2024.100545 · Cited by 1
Disorders Specifically Associated with Stress: PTSD, Complex PTSD, Prolonged Grief Disorder, Acute Stress Reaction, Adjustment Disorder
Blakey, S. M., Dillon, K. H., McFARLANE, A. C., & Beckham, J. C. (2024) · Springer eBooks · doi:10.1007/978-3-030-51366-5_59 · Cited by 1
INNOVATIVE MICROBIAL-BASED THERAPIES FOR POST-TRAUMATIC STRESS DISORDER
LYPEY, І. M. (2024) · Biotechnologia Acta · doi:10.15407/biotech17.05.014 · Cited by 1
The association between inflammatory markers and psychological disorders in veterans and military personnel: a systematic review protocol
Bennett, N., Davy, C. P., Lawrence‐Wood, E., & McFARLANE, A. C. (2015) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2015-2022 · Cited by 1
Post-traumatic stress symptoms following childhood sepsis: The impact of inflammation and corticosteroids
Burcher, G. C., Caspani, G., Cooper, M., Pierce, C. M., Als, L. C., Garralda, M. E., & Nadel, S. (2019) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.11.693 · Cited by 1
Surgery on the Incarcerated Patient
Beyer, T. D., & Applewhite, M. K. (2022) · Difficult decisions in surgery: an evidence-based approach · doi:10.1007/978-3-030-84625-1_21 · Cited by 1
Exercise and Posttraumatic Stress Disorder
Rosenbaum, S., Stubbs, B., Schuch, F. B., & Vancampfort, D. (2017) · Springer eBooks · doi:10.1007/978-3-662-49411-0_16-1 · Cited by 3
Peritraumatic Behavior Questionnaire
Agorastos, A., Angkaw, A. C., Johnson, H. E., Hansen, C. J., Cook, C. V., & Baker, D. G. (2015) · Springer eBooks · doi:10.1007/978-3-319-08613-2_102-1 · Cited by 2
Self-citation
Spotlight: An Interview with Dr. Christopher A. Lowry, on the Convergence of Microbes, Nature, and Mental Health
Logan, A. C., & Lowry, C. A. (2022) · Challenges · doi:10.3390/challe13020051 · Cited by 2
Hippocampal Volumes in PTSD
Chao, L. L. (2016) · Springer eBooks · doi:10.1007/978-3-319-08359-9_99 · Cited by 1
Potential Neuroprotective Effects of Natural Anti-NMDAR1 Autoantibodies Against Psychiatric Symptoms Associated with Traumatic Brain InjuriesPreprint
Vaughn, M. N., Acheson, D. T., Powell, S. B., Yurgil, K. A., Nievergelt, C. M., Baker, D. G., Risbrough, V. B., & Zhou, X. (2026) · medRxiv · doi:10.64898/2026.01.08.26343690 · Cited by 1
Self-citation
Peritraumatic Behavior Questionnaire
Agorastos, A., Angkaw, A. C., Johnson, H. E., Hansen, C. J., Cook, C. V., & Baker, D. G. (2016) · Springer eBooks · doi:10.1007/978-3-319-08359-9_102
Self-citation
Postulating Traumatic Stress Disorders
Stein, M. B. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.06.018
Relating C-reactive Protein to Psychopathology after Cardiac Surgery and Intensive Care Unit Admission: A Mendelian Randomization StudyPreprint
Kok, L., Lin, B. D., Broersen, J. L., Bekema, E., Medic, J., van Eijk, K. R., Hillegers, M. H. J., Veldhuijzen, D. S., & Luykx, J. J. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/196790
Genetic, Biomarker and Psychological Factors for Risk and Resilience of PTSD
Bruenig, D. (2017) · Queensland University of Technology · doi:10.5204/thesis.eprints.112180
LincRNAs involved in DCS-induced fear extinction: Shedding light on the transcriptomic dark matterPreprint
Malan‐Müller, S., de Souza, V. B. C., Daniels, W. M. U., Seedat, S., Robinson, M. D., & Hemmings, S. M. J. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/834242
Correlation between Inflammatory Markers and Liver Enzymes in Patients with Post-Traumatic Stress Disorder
Fajkić, A., Mušanović, J., Lepara, O., Musić, M., Pepić, E., Džubur, A., Džubur, A., & Lisica, D. (2021) · Journal of Evolution of Medical and Dental Sciences · doi:10.14260/jemds/2021/108
The Immune System and Anxiety Disorders
Michopoulos, V., & Jovanović, T. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108539623.013
Akute und posttraumatische Belastungsstörung
Kapfhammer, H. (2016) · Springer eBooks · doi:10.1007/978-3-642-45028-0_71-1 · Cited by 1
The interplay between the genome and the exposome in psychosis spectrum
Pries, L.-K. (2020) · Research Publications (Maastricht University) · doi:10.26481/dis.20201211lp
References
(2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811351-6.00026-7
Hippocampal Volumes in PTSD
Chao, L. L. (2015) · Springer eBooks · doi:10.1007/978-3-319-08613-2_99-1
Adverse Human Health Outcomes Associated with Psychologi-cal Trauma: A review
Jan, Z., Gostečnik, C., & Kralj‐Iglič, V. (2022) · Socratic Lectures · doi:10.55295/psl.2022.d7
Socratic Lectures 7
(2022) · doi:10.55295/psl.2022.d
Examining Neuroendocrine and Inflammatory Biomarker Profiles to Characterize PTSD Subtypes and Symptom Profiles.
Jarkas, D. (2022) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2022-15321
Review: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R0/PR2
Schmidt, M. A., Jones, J. A., & Mason, C. E. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr2
Decision: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R1/PR9
Schmidt, M. A., Jones, J. A., & Mason, C. E. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr9
Recommendation: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R0/PR4
Schmidt, M. A., Jones, J. A., & Mason, C. E. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr4
Author comment: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R0/PR1
Schmidt, M. A. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr1
Recommendation: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R1/PR8
Schmidt, M. A., Jones, J. A., & Mason, C. E. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr8
Author comment: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R1/PR6
Schmidt, M. A. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr6
Review: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R1/PR7
Schmidt, M. A., Jones, J. A., & Mason, C. E. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr7
Review: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R0/PR3
Schmidt, M. A., Jones, J. A., & Mason, C. E. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr3
Decision: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R0/PR5
Schmidt, M. A., Jones, J. A., & Mason, C. E. (2023) · Cambridge Prisms Precision Medicine · doi:10.1017/pcm.2023.16.pr5
Inflammation and traumatic stress
Hori, H., & Hakamata, Y. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-817558-3.00015-9
Transcutaneous Vagal Nerve Stimulation in Trauma Spectrum Psychiatric Disorders
Bremner, J. D., Wittbrodt, M. T., Gurel, N. Z., Shandhi, M. M. H., Gazi, A. H., Park, J., & Inan, O. T. (2023) · Neuromethods · doi:10.1007/978-1-0716-3465-3_8
Sex and gender differences in risk factors for post-traumatic stress disorder: a systematic review and meta-analysis of prospective studiesPreprint
Haering, S., Meyer, C., Schulze, L., Conrad, E., Blecker, M. K., El‐Haj‐Mohamad, R., Geiling, A., Klusmann, H., Schumacher, S., Knaevelsrud, C., et al. (2023) · doi:10.31234/osf.io/hfqt2
Disorders Specifically Associated with Stress: PTSD, Complex PTSD, Acute Stress Reaction, Adjustment Disorder
Blakey, S. M., Dillon, K. H., McFARLANE, A. C., & Beckham, J. C. (2023) · Springer eBooks · doi:10.1007/978-3-030-42825-9_59-1 · Cited by 1
The Future of Psychiatry
Correia, J., Cavaco, T. B., & Catanho, J. (2024) · Gazeta Médica · doi:10.29315/gm.v1i1.838
Effects of Electroencephalogram Neurofeedback Intervention on Blood C-Reactive Protein Levels in Astronauts Attending 2-Week Long Analog Moon Mission
Hinca, J., & Dornowski, M. (2024) · Brain Sciences · doi:10.3390/brainsci14080843
References
(2024) · Elsevier eBooks · doi:10.1016/b978-0-443-23565-8.09996-8
Posttraumatic Stress Disorder
Anisman, H., Hayley, S. P., & Kusnecov, A. W. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-23565-8.00010-7
The Moderating Effect of Resilience on the Relationship Between the Relevance to Victims With Post-Trauma Psychiatric Symptoms of Community Residents After Seoul Halloween Crowd Crush
Kim, S. Y., Jung, S., Lee, M.-Y.-O., Oh, K.-S., Shin, Y., Shin, D., Kim, J., Kim, E. S., Jung, S. W., Lee, K.-Y., et al. (2024) · Psychiatry Investigation · doi:10.30773/pi.2024.0154
The Role of the Immune System in Creating Depression, Post-traumatic-Stress-Disorder, and Psychosis
Littrell, J. L. (2024) · Integrated science · doi:10.1007/978-3-031-72079-6_2
Post-traumatic stress disorder moderates the association between BrainAge acceleration and GrimAge acceleration
Beakas, J., Dwulit, A. K., Hussain, A. T., Garrett, M. E., Ashley‐Koch, A. E., Clausen, A. N., Harnett, N. G., Ressler, K. J., van Rooij, S. J. H., Stevens, J. S., et al. (2026) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2026.05.010 · Cited by 1
Body Mass Index and Risk of Post-Traumatic Stress Disorder: A Cohort Study of 1.4 Million Late Adolescents
Abuhasira, S., Tatsa-Laur, L., & Shelef, L. (2025) · Military Medicine · doi:10.1093/milmed/usaf334
Neurobiology of post-traumatic stress disorder
Đorović, Đ., & Puškaš, L. (2025) · Medicinski podmladak · doi:10.5937/mp76-49506 · Cited by 1
Research Progress in Pharmacological Treatment of Post-Traumatic Stress Disorder
柯, 苹. (2025) · Advances in Psychology · doi:10.12677/ap.2025.159532
Ibudilast perpetuates stress-induced anxiety-like behavior and fear memory expression in adult Sprague-Dawley rats
Enga, R. M., Naderi, A. O., Scott, E. M., Coachman, K. D., Silva, G. M., Bergman, E. M., May, M. D., Batuure, A., Fenlon, N. S., DeMar, J. C., et al. (2025) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/j.jpet.2025.103746
Additional file 1 of Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice
Li, S., Liao, Y., Dong, Y., Li, X., Li, J., Cheng, Y., Cheng, J., & Yuan, Z. (2021) · Figshare · doi:10.6084/m9.figshare.13525292
Additional file 1 of Contact with primary care physicians among adults with pre-existing common mental health problems during the COVID-19 pandemic: a registry-based study from Norway
Jensen, P., Madsen, C., Hauge, L. J., Gustavson, K., Lund, I. O., Pettersen, J. H., Knudsen, A. K., Reneflot, A., Brandlistuen, R. E., Valdimarsdóttir, U. A., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24295667
Pharmacological aspects of biological drugs for the treatment of posttraumatic stress disorder
LYPEY, І. M. (2025) · Biotechnologia Acta · doi:10.15407/biotech18.06.005
Gut microbiota: a perspective for post-traumatic stress disorder
Soleimani, R. A. (2025) · Gastrointestinal Nursing · doi:10.12968/gasn.2025.0071
Riesgo cardiovascular asociado al trastorno de estrés postraumático: revisión narrativa y llamado a la acción en Colombia
Salamanca, A. F. D. (2025) · Revista de la Facultad de Ciencias de la Salud Universidad del Cauca · doi:10.47373/rfcs.2025.v27.2613
Time-dependent associations between early high-sensitivity C-reactive protein levels and post-traumatic stress disorder after physical injury
Kim, J., Kang, H.-J., Kim, J.-W., Lee, J.-Y., Jang, H., Kim, J.-C., Kim, S.-W., & Shin, I.-S. (2026) · Psychiatry Research · doi:10.1016/j.psychres.2026.117005
Association between steatotic liver disease and post-traumatic stress symptoms in the Fukushima health management survey
Hayashi, F., Ohira, T., Takahashi, A., Ueda, Y., Nakano, H., Okazaki, K., Nagao, M., Sato, S., Maeda, M., Miura, I., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-41265-0
Travma Sonrası Stres Bozukluğu Hastalarında İnterlökin-4, İnterlökin-17, İnterferon-Gama ve Beyaz Kan Hücre Düzeyleri ile Sosyodemografik Özelliklerin İncelenmesi
AYDAR, S., Günes, M., & Mete, N. (2026) · Dicle Medical Journal / Dicle Tip Dergisi · doi:10.5798/dicletip.1906536
Inflammatory biomarker outcomes associated with MDMA-assisted therapy: an open-label exploratory study
Kachmarik, J. E., Loftis, J. M., & Stauffer, C. S. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1716817
The role of gut microbiome in the pathophysiology of PTSD, depression, and anxiety disorders
Nto, N. J., Pirovano, W., Zyl, K. N. V., Malan‐Müller, S., Koch, E., Ramaboli, M. C., Madikgetla, D., de Leeuw, C., Lowry, C. A., & Hemmings, S. M. J. (2026) · Gut Microbes Reports · doi:10.1080/29933935.2026.2654224
C3 and C5 complement cascade activation in brain injury and disease: Molecular mechanisms, pathological roles, and therapeutic implications
Woodard, G. E. (2026) · Neurochemistry International · doi:10.1016/j.neuint.2026.106161
A novel soil-derived Mycolicibacterium decreases anxiety-like defensive behavioral responses in association with decreases in biomarkers of neuroinflammation and hippocampal microglial priming in adult male rats
Zhang, H., Marquart, B. M., Holbrook, E. M., Wright, C. T. O., Zambrano, C. A., Gebert, M. J., Dawud, L. M., Andersen, N. D., Kessler, L. R., Sago, S. A., et al. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.106809
Factors Influencing Health-related Quality of Life in Adults with Accident or Poisoning Related Treatment Experience in The Past Year: Analysis of the 2023 Korea National Health and Nutrition Examination Survey
Baek, H. J., & Gang, M. (2026) · Journal of Korean Academy of Fundamentals of Nursing · doi:10.7739/jkafn.2026.33.2.211
Neuroimmune mechanisms in PTSD: inflammatory heterogeneity, circuit dysfunction, and biomarker-based subtypes
Majumdar, S., Samaiya, P. K., Ahmed, S., Krishnamurthy, S., & Prajapati, S. K. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-12032-1
Sex-specific contribution of endothelial AT1aRs to avoidance behaviors and BBB changes in a mouse model of PTSD
Levesque, P., Canivet, C., Drolet, M., Martel, J., Risbrough, V. B., & Deslauriers, J. (2026) · Neurobiology of Disease · doi:10.1016/j.nbd.2026.107547
Posttraumatic stress disorder as a conditional transition outcome: an integrative theoretical review of non-transition, maintenance, and recovery
Sarapultsev, A., Komelkova, M. V., Gusev, E., Hu, D., & Черешнев, В. А. (2026) · European Journal of Trauma & Dissociation · doi:10.1016/j.ejtd.2026.100738
A scoping review of the longitudinal association between posttraumatic stress disorder and cardiometabolic health in military populations
Shank, L. M., Nair, R., Kalish, R. L., Cowansage, K. K., Boyd, C., Bellanti, D. M., Milligan, T., Richmond, A., & Kelber, M. S. (2026) · Journal of Traumatic Stress · doi:10.1002/jts.70123
Natural anti–NMDAR1 autoantibodies are associated with lower risk for depression and PTSD symptoms after traumatic brain injury
Vaughn, M. N., Acheson, D. T., Powell, S. B., DeWit, J. M., Yurgil, K. A., Nievergelt, C. M., Baker, D. G., Risbrough, V. B., & Zhou, X. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03883-y
Self-citation
Pre- and peri-traumatic risk factors associated with inflammatory and antiviral gene expression after traumatic injury
Tomas, C. W., Timmer‐Murillo, S. C., Cole, S. W., Larson, C. L., & deRoon‐Cassini, T. A. (2026) · Brain and Environment · doi:10.1016/j.braen.2026.100034
Immunometabolic alterations in post-traumatic stress disorder
Brasanac, J., El‐Ahmad, L., Mollerup, E., Gamradt, S., Gruenberg, L., Shyshko, D., Stiglbauer, V., Zimbalski, K., Schoofs, N., Priebe, K., et al. (2026) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2026.107031
Ist C-reaktives Protein im Plasma ein Biomarker für das PTBS-Risiko nach Traumatisierung?
Kellner, M. B. (2014) · InFo Neurologie + Psychiatrie · doi:10.1007/s15005-014-0920-5

Authors: Eraly, S. A., Nievergelt, C. M., Maihofer, A. X., Barkauskas, D. A., Biswas, N., Agorastos, A., O’Connor, D. T., & Baker, D. G.
Affiliations: University of California San Diego (US)
University of Southern California (US)
University Medical Center Hamburg-Eppendorf (DE)
Corresponding author: Baker, Dewleen G.
ORCID: Nievergelt, Caroline M.
Maihofer, Adam X.
Barkauskas, Donald A.
Biswas, Nilima
Agorastos, Agorastos
Baker, Dewleen G.
Venue: JAMA Psychiatry
Publisher: American Medical Association (AMA)
Published: 2014-04-01
Volume: 71
Issue: 4
Pages: 423
ISSN: 2168-622X (ISSN-L)
DOI: 10.1001/jamapsychiatry.2013.4374
PMC: PMC4032578
OpenAlex: W2100635378
Cited by: 386
References: 81
Citations by year: 2026: 20 · 2025: 28 · 2024: 33 · 2023: 47 · 2022: 36 · 2021: 28 · 2020: 27 · 2019: 22 · 2018: 29 · 2017: 37 · 2016: 39 · 2015: 30 · 2014: 10
FWCI: 45.63
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: JAMA Psychiatry (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
eScholarship (California Digital Library) (submittedVersion)
Funders: National Heart, Lung, and Blood Institute (R01HL094728, HL094728)
National Institute of Mental Health (MH093500, R01MH093500)
Topics: Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
Keywords: post-traumatic stress disorder, C-reactive protein, biomarkers, peripheral inflammation, combat deployment, military personnel, PTSD risk prediction, zero-inflated negative binomial regression, Clinician-Administered PTSD Scale, PTSD symptom severity, PTSD prevention
MeSH terms: Adult, C-Reactive Protein, Combat Disorders, Humans, Inflammation, Longitudinal Studies, Male, Military Personnel, Neuropsychological Tests, Predictive Value of Tests, Prospective Studies, Stress Disorders, Post-Traumatic, Biomarkers, Risk Assessment, Resilience, Psychological

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Assessment of Plasma C-Reactive Protein as a Biomarker of Posttraumatic Stress Disorder Risk

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks