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A Solution-Focused Research Approach to Achieve an Implementable Revolution in Digital Mental Health
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“Examining trends also adds to evidence regarding iCBT in routine care as there are few reports of iCBT outcomes sustained over longer periods after initial implementation efforts conclude. 35”
From Utilization, Patient Characteristics, and Longitudinal Improvements among Patients from a Provincially Funded Transdiagnostic Internet-delivered Cognitive Behavioural Therapy Program: Observational Study of Trends over 6 Years (2022) · cites this paper as [35]
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“Yet, despite evidence from 15 years of research for the effectiveness of digital mental health interventions, a historical and global research translation gap has hindered clinical implementation, and very few digital interventions have been successfully integrated into mental services.”
From The Lancet Psychiatry Commission on youth mental health (2024) · cites this paper as [364]
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“40 Real-world implementation of digital technologies often fails because they are not used by patients or do not fit within clinical practice.”
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“Risiken und Chancen sektorenübergreifender Therapiekonzepte und innovativer Technologien Obwohl wir vielversprechende Befunde zu sektorenübergreifendenTherapiekonzepten und innovativen Technologien in der Versorgung von Menschen mit psychischen Störungen identifiziert haben, haben sowohl die vorliegende selektive Über…”
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“…and intention to use, potentially constituting a barrier to reaching the full potential of these services (Apolinário-Hagen et al., 2018; Klein & Cook, 2010; Mohr, Riper, & Schueller, 2018; Musiat, Goldstone, & Tarrier, 2014; Wahbeh, Svalina, & Oken, 2014; Wallin, Mattsson, & Olsson, 2016).”
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The AI Integration Matrix: a Framework for Responsible Artificial Intelligence in Mental Health
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“To address these barriers, digital mental health interventions (DMHIs) have rapidly emerged as scalable, accessible alternatives [5].”
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“DMHIs that have both patient- and CC-facing features (1) allow patients to engage in relevant therapeutic modules between provider visits, increasing the resources for symptom self-management; (2) enhance CC’s provision of care by providing decision support tools that can help CCs follow appropriate procedures when wo…”
BackgroundSelf-citationAspect of Artificial Intelligence in Dealing with Mental Health Disorders in Adolescents
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“…health resources are limited, programs utilizing novel approaches such as experiential interventions have been shown to offer substantial benefits to diverse clientele (Arjadi et al., 2018; Burns et al., 2016; Firth et al., 2017; Freeman et al., 2017; Mohr et al., 2018; Yulinda et al., 2023).”
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“In digital mental health research, for instance, it is perceived as a required paradigm shift necessary to overcome multiple failures in current research design, and is expected to produce more ground-breaking results (Mohr et al., 2018).”
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Examining Provider Factors Supporting the Adoption and Use of Research-Supported Interventions
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Optimizing implementation of patient-centered innovations Learning from cancer care practice
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Can digital tools improve clinical care in psychiatry?
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This document will be updated.Preprint
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Adolescent Mental Health Care: Time for Revolution
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“Participatory design can also help ensure compatibility of program-led tools with the routines and constraints of both users and providers, enhancing individual engagement and system-level integration (Mohr et al. 2018).”
Shah, A., Feroz, A. S., Sheehan, K., Wright, S., Nolan, R. P., Strudwick, G., Sockalingam, S., & Seto, E. (2025) · doi:10.2196/preprints.82139
Рафиковна, Х. З., Plotnikov, A., Kelareva, I., & Gani, S. V. (2025) · Communications in computer and information science · doi:10.1007/978-3-032-04958-2_21
Razmak, J., & Farhan, W. (2025) · Information Discovery and Delivery · doi:10.1108/idd-02-2025-0036
Han, Y.-S., Wang, W., Hu, J., Hu, J., Xu, X., Ai, M., Hong, S., & Kuang, L. (2025) · JMIR Formative Research · doi:10.2196/88824
Finkbeiner, M., Kühnhausen, J., Schmid, J., Conzelmann, A., Dürrwächter, U., Wahl, L.-M., Kelava, A., Gawrilow, C., & Renner, T. J. (2022) · Figshare · doi:10.6084/m9.figshare.20677865
When Lived Experience Designs the Intervention
van Mierlo, T. (2026) · Journal of Medical Internet Research · doi:10.2196/91371
Digital Interventions for Improving Mental Health and Well-Being in Young People
Katsikidou, M. (2026) · Springer eBooks · doi:10.1007/978-3-032-08980-9_10
Antepartum and Postpartum Mental Health Issues
Camoni, L., Bernardini, C., Gigantesco, A., & Mirabella, F. (2026) · Springer eBooks · doi:10.1007/978-3-032-08980-9_20
Adaptive Mental Health Interventions: Integrating VR and Generative AI in Learning Environments
Greca, A. D., Amaro, I., & Barra, P. (2026) · Lecture notes in computer science · doi:10.1007/978-3-032-17604-2_1
Shah, A., Feroz, A. S., Sheehan, K., Wright, S., Nolan, R. P., Strudwick, G., Sockalingam, S., & Seto, E. (2026) · JMIR Formative Research · doi:10.2196/82139
“Despite this potential and the effectiveness of virtual mental health interventions in controlled research settings for people living with complex chronic conditions, their uptake and integration into real-world clinical care have remained limited [11-13].”
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Jerome, L., Adams, K., Bird, V., & Ougrin, D. (2026) · PLOS Digital Health · doi:10.1371/journal.pdig.0001276
“Understanding users’ lived experiences can uncover their requirements, challenges, and any potential barriers or facilitators to engagement that may otherwise be overlooked [7–12].”
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“Across clinical, educational, and organizational settings, recurring concerns include privacy, algorithmic bias, transparency, accountability, and safety [7,16,29,40].”
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“For DTx product development, optimization might prioritize facilitating real-world behavioral internalization through adaptive content delivery and habit-change reinforcement rather than maximizing session frequency or time-on-app [33-35].”
A Randomized Controlled Trial of A Gamified Digital Mental Health Intervention for Child Anxiety
Kriegshauser, K. D., Larsen, M. A., Sharma, A., Pine, A. E., Leoutsakos, J., Hale, L. R., & Mcguire, J. F. (2026) · Child Psychiatry & Human Development · doi:10.1007/s10578-026-02097-1
Metadata
- Authors
- Mohr, D. C., Riper, H., & Schueller, S. M.
- Affiliations
- Northwestern University (US)
- Vrije Universiteit Amsterdam (NL)
- Venue
- JAMA Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2018-02-01
- Volume
- 75
- Issue
- 2
- Pages
- 113
- ISSN
- 2168-622X (ISSN-L)
- OpenAlex
- W2772874515
- Cited by
- 204
- References
- 7
- Citations by year
- 2026: 21 · 2025: 28 · 2024: 27 · 2023: 19 · 2022: 26 · 2021: 29 · 2020: 25 · 2019: 20 · 2018: 9
- FWCI
- 16.89
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (submittedVersion, other-oa)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (submittedVersion)
- VU Research Portal (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Keywords
- digital mental health, implementation, digital health interventions, mental health technology
- MeSH terms
- Mental Disorders, Computers, Forecasting, Health Plan Implementation, Humans, Mental Health Services, Motivation, Patient Acceptance of Health Care, Therapy, Computer-Assisted, Randomized Controlled Trials as Topic, Treatment Outcome, Biomedical Research, Mobile Applications
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