Cognitive Impairment and Depression-Cause, Consequence, or Coincidence?
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Cognitive impairment may be implicated in the pathogenesis of depressive symptoms.
“While cognitive impairment may be implicated in the pathogenesis of depressive symptoms [222]”
From Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature (2021) · cites this paper as [222]
Factors such as low cognitive ability/function, cognitive vulnerability, cognitive impairment or deficits, subjective cognitive decline, regression of dendritic branching and hippocampal atrophy/death of hippocampal cells, impaired neuroplasticity, and neurogenesis-related aspects have been linked to depression.
“The results show that factors, such as low cognitive ability/function, cognitive vulnerability, cognitive impairment or deficits, subjective cognitive decline, regression of dendritic branching and hippocampal atrophy/death of hippocampal cells, impaired neuroplasticity, and neurogenesis-related aspects, have been linked to depression [131,212,222,223,224,225,226,227,228,229,230,231,232,233,234,2”
From Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature (2021) · cites this paper as [222]
According to the 'cognitive neuropsychological' model of depression, negative affective biases play a central part in the development of depression.
“according to the ‘cognitive neuropsychological’ model of depression, negative affective biases play a central part in the development of depression [222,241].”
From Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature (2021) · cites this paper as [222]
A family history of cognitive impairment (in first degree relatives) is linked to depression.
“Halahakoon et al. [222] note a meta-analysis [240] that shows that a family history of cognitive impairment (in first degree relatives) is also linked to depression.”
From Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature (2021) · cites this paper as [222]
Negative information processing biases are important in depression.
“negative information processing biases are also important”
From Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature (2021) · cites this paper as [222]
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
eQTLGen, Wray, N. R., 23andMe, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., et al. (2018) · Nature Genetics · doi:10.1038/s41588-018-0090-3 · Cited by 3,005 · see citing works
Cognitive impairment in depression: a systematic review and meta-analysis
Rock, P. L., Roiser, J. P., Riedel, W. J., & Blackwell, A. D. (2014) · Psychological Medicine · doi:10.1017/s0033291713002535 · Cited by 2,161 · see citing works
Self-citationThe Genetic Basis of Complex Human Behaviors
Plomin, R. J., Owen, M. J., & McGuffin, P. (1994) · Science · doi:10.1126/science.8209254 · Cited by 1,021 · see citing works
Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Michelle Luciano, A., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns‐Ritchie, C., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04362-x · Cited by 668 · see citing works
Cognitive Mechanisms of Treatment in Depression
Roiser, J. P., Elliott, R., & Sahakian, B. J. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.183 · Cited by 535 · see citing works
Self-citationConradi, H. J., Ormel, J., & de Jonge, P. (2011) · Psychological Medicine · doi:10.1017/s0033291710001911 · Cited by 515 · see citing works
The timing of maternal depressive symptoms and child cognitive development: a longitudinal study
Evans, J., Melotti, R., Heron, J., Ramchandani, P., Wiles, N., Murray, L., & Stein, A. (2012) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2011.02513.x · Cited by 184 · see citing works
Stanley, C. A., Murray, L., & Stein, A. L. (2004) · Development and Psychopathology · doi:10.1017/s0954579404044384 · Cited by 173 · see citing works
Pearson, R. M., Bornstein, M. H., Cordero, M., Scerif, G., Mahedy, L., Evans, J., Abioye, A., & Stein, A. L. (2015) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12483 · Cited by 133 · see citing works
Scult, M. A., Paulli, A. R., Mazure, E. S., Moffitt, T. E., Hariri, A. R., & Strauman, T. J. (2016) · Psychological Medicine · doi:10.1017/s0033291716002075 · Cited by 121 · see citing works
MacKenzie, L. E., Uher, R., & Pavlova, B. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.3672 · Cited by 60 · see citing works
Glaser, B., Gunnell, D., Timpson, N. J., Joinson, C. J., Zammit, S., Smith, G. D., & Lewis, G. (2010) · Psychological Medicine · doi:10.1017/s0033291710000814 · Cited by 35 · see citing works
Self-citationSchaefer, J. D., Scult, M. A., Caspi, A., Arseneault, L., Belsky, D. W., Hariri, A. R., Harrington, H., Houts, R., Ramrakha, S., Poulton, R., et al. (2017) · Development and Psychopathology · doi:10.1017/s095457941700164x · Cited by 26 · see citing works
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2 of the 17 references couldn’t be matched to a known paper.
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Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature
Remes, O., Mendes, J. F., & Templeton, P. (2021) · Brain Sciences · doi:10.3390/brainsci11121633 · Cited by 482 · see citing works
Air pollution and human cognition: A systematic review and meta-analysis
Thompson, R., Smith, R. B., Karim, Y. B., Shen, C., Drummond, K., Teng, C., & Toledano, M. B. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.160234 · Cited by 118 · see citing works
Coughlan, G., Zhukovsky, P., Puthusseryppady, V., Gillings, R., Minihane, A. M., Cameron, D., & Hornberger, M. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.02.007 · Cited by 32 · see citing works
A computational approach to understanding effort-based decision-making in depression
Valton, V., Mkrtchian, A., Moses-Payne, M. E., Gray, A., Kieslich, K., VanUrk, S., Samborska, V., Halahakoon, D. C., Manohar, S., Dayan, P., et al. (2025) · Psychological Medicine · doi:10.1017/s0033291725101967 · Cited by 26 · see citing works
Self-citationZhou, X., & Wu, H. Y. (2023) · Journal of Global Health · doi:10.7189/jogh.13.04068 · Cited by 24 · see citing works
Hong, X. L., Cheng, L. J., Feng, R. C., Goh, J., Gyanwali, B., Itoh, S., Tam, W., & Wu, X. V. (2023) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2023.105161 · Cited by 19 · see citing works
Ethics and the impossibility of the consent form: Ethnography in a Danish nursing home
Balkin, E. J., Kollerup, M. G., Kymre, I. G., Martinsen, B., & Grønkjær, M. (2023) · Journal of Aging Studies · doi:10.1016/j.jaging.2023.101110 · Cited by 18 · see citing works
Borelli, W. V., Zimmer, E. R., Bieger, A., Coelho, B. B., Pascoal, T. A., Chaves, M. L. F., Amariglio, R. E., & Castilhos, R. M. (2022) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12368 · Cited by 17 · see citing works
The Prevalence of Cognitive Impairment and Dementia in Incarcerated Older Adults
Baillargeon, J., Linthicum, L. C., Murray, O. J., Raji, M. A., Kuo, Y., Pulvino, J. S., Milani, S. A., Williams, B. A., Baillargeon, G. M., Blair, P. A., et al. (2023) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbad136 · Cited by 16 · see citing works
Kaur, A., Sonal, A., Ghosh, T. K., & Ahamed, F. (2023) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_2458_22 · Cited by 16 · see citing works
Speech as a Biomarker for Disease Detection
Botelho, C., Abad, A., Schultz, T., & Trancoso, I. M. (2024) · IEEE Access · doi:10.1109/access.2024.3506433 · Cited by 15 · see citing works
Dao, L., Wang, K., Yang, Z., Li, H., & Wang, S. (2021) · PubMed Central · Cited by 15 · see citing works
Zang, J. C. S., Hohoff, C., Assche, E. V., Lange, P., Kraft, M., Sandmann, S., Varghese, J., Jörgens, S., Knight, M. J., & Baune, B. T. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110826 · Cited by 12 · see citing works
Tarantini, L., Möller, C., Schiestl, V., Sordon, S., Noll‐Hussong, M., Wittemann, M., Menzie, N., & Riemenschneider, M. J. (2025) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-025-01978-1 · Cited by 11 · see citing works
Risk Factors for Incident Dementia Among Older Cubans
Peeters, G. M. E. E., Almirall‐Sánchez, A., Guerra, J. L., LAWLOR, B. A., Kenny, R. A., Yaffe, K. S., & Rodríguez, J. J. L. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.00481 · Cited by 11 · see citing works
Bao, C., Wang, Y., Le, T. T., Xu, L., Tang, W., Zou, W., Bao, Y., Xu, D., & Zhao, K. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-04976-6 · Cited by 10 · see citing works
de Cates, A. N., Martens, M., Wright, L. C., Gibson, D., Spitz, G., van Praag, C. G., Suri, S., Cowen, P. J., Murphy, S. E., & Harmer, C. J. (2023) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2023.03.014 · Cited by 9 · see citing works
Association between age-related macular degeneration and subjective cognitive complaints
Zhu, Z., Liao, H., Wang, W., Scheetz, J., Zhang, J., & He, M. (2019) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2019-314853 · Cited by 9 · see citing works
Jin, L., & Jing, F. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1415715 · Cited by 8 · see citing works
Cognitive abilities of institutionalized older persons with depressive symptoms
Felício, L. F. F., Leão, L. L., Souza, E. H. E. E., Machado, F. S. M., Laks, J., Deslandes, A. C., de Paula, A. M. B., & Monteiro-Júnior, R. S. (2022) · Jornal Brasileiro de Psiquiatria · doi:10.1590/0047-2085000000383 · Cited by 8 · see citing works
Dai, M., Song, Q., Wang, X., Li, Y., Lin, T., Liang, R., Jiang, T., Shu, X., Ge, N., & Yue, J. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1024341 · Cited by 7 · see citing works
Li, J., Li, J., Shen, L., Wang, H., Tian, Z., Hui, Y., & Li, X. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1196055 · Cited by 7 · see citing works
Distinctive neuropsychological profiles of lateral temporal lobe epilepsy
Longo, A., Houot, M., Herlin, B., Méré, M., Denos, M., Samson, S., & Dupont, S. (2021) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2021.108411 · Cited by 7 · see citing works
Genetic similarities and differences among distinct definitions of depression
Wu, Y., Wang, L., Zhang, C., Li, M., & Li, Y. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114843 · Cited by 6 · see citing works
Executive functioning in matrescence and implications for perinatal depression
Ghadimi, T. R., & McCormack, C. A. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1663017 · Cited by 5 · see citing works
Li, W., Hu, N., Yang, X., Zheng, W., Tong, J., Song, J., Song, Y., Gao, X., Wang, Z., Liu, W., et al. (2025) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s524185 · Cited by 5 · see citing works
Balqis-Ali, N. Z., Ahmad, N., Minhat, H. S., & Azman, A. Z. F. (2024) · BMC Geriatrics · doi:10.1186/s12877-024-05211-x · Cited by 4 · see citing works
Komalasari, R., Mpofu, E., (Chang), H. C. (., Tallutondok, E. B., Uligraff, D. K., Zhan, R., & Thiamwong, L. (2024) · SAGE Open Nursing · doi:10.1177/23779608241296629 · Cited by 4 · see citing works
Kosovo sexual minorities: A mental health crisis
Llullaku, N., Selimi, R., Roest, J. J., & van der Helm, P. (2023) · Journal of Gay & Lesbian Mental Health · doi:10.1080/19359705.2023.2213217 · Cited by 4 · see citing works
Li, G., Wang, R. L., Fu, T., Tong, S., & Tian, F. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1552165 · Cited by 3 · see citing works
Pike, A. C., Rowan Board, Travers, E., Croal, M., Lam, Y. C., Valton, V., Robinson, O. J., & Roiser, J. P. (2026) · Psychological Medicine · doi:10.1017/s0033291726105340 · Cited by 3 · see citing works
Self-citationde la Fuente, D., Könen, T., In‐Albon, T., Schemer, L., & Karbach, J. (2024) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2024.100812 · Cited by 3 · see citing works
Alcohol, Depression, and Anxiety
Onaemo, V. N., & Chireh, B. (2024) · Springer eBooks · doi:10.1007/978-3-031-32046-0_130-1 · Cited by 3 · see citing works
Pro-cognitive effects of 5-HT4 receptor agonism in individuals with remitted depression
de Cates, A. N., Hamilton, S., Guru, A., Blandhol, M., Colwell, M., Cowen, P. J., Simmons, M., Jones, B., Harmer, C. J., & Murphy, S. E. (2026) · Psychological Medicine · doi:10.1017/s0033291726104450 · Cited by 2 · see citing works
Depressive Realism and Analyst Forecast Accuracy
Jannati, S., Khalaf, S., & Nguyen, D. (2020) · Journal of Banking & Finance · doi:10.1016/j.jbankfin.2025.107526 · Cited by 2 · see citing works
Alcohol, Depression, and Anxiety
Onaemo, V. N., & Chireh, B. (2025) · Springer eBooks · doi:10.1007/978-3-031-73363-5_130 · Cited by 1 · see citing works
Yuan, B., & Yiengprugsawan, V. (2019) · Community Mental Health Journal · doi:10.1007/s10597-019-00461-1 · Cited by 1 · see citing works
Studying cognitive function in patients with a long-standing diagnosis of SWEDD
Jesuthasan, A., Garcia, L. R., & Pavese, N. (2022) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2022.120353 · Cited by 1 · see citing works
Nicholas, P. (2020) · Queensland University of Technology · doi:10.5204/thesis.eprints.203098
Natukunda, H. P. M., Toska, E., Boyes, M. E., Sherr, L., Hoare, J., Nightingale, S., & Cluver, L. D. (2020) · doi:10.21203/rs.3.rs-71577/v1
Alsulaiman, F. A., Alabdali, M. M., Aljaafari, D., Alsulaiman, A. A., Alzahrani, S. I., Alyahya, R. M., Alshurem, M., Alsulaiman, A. A., & Ghamdi, O. A. (2025) · Annals of African Medicine · doi:10.4103/aam.aam_258_24
Zhang, W., Sun, H., Feng, Y., Sha, S., Su, Z., Cheung, T. C. C., Ungvari, G. S., Jackson, T., Zhang, Q.-E., & Xiang, Y. (2025) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/08919887251360261
de Cates, A. N., Lee, A. H. Y., Winchester, L. M., Ebmeier, K. P., Lalousis, P. A., Upthegrove, R., Murphy, S. E., Harmer, C. J., Nichols, T. E., & Topiwala, A. (2026) · BMJ Mental Health · doi:10.1136/bmjment-2025-302332
Liu, W., Yu, Y., Zheng, W., Song, W., Fu, Y., Di, Y., Li, S., Liu, Z., Wang, L., Yang, X., et al. (2026) · Current Psychology · doi:10.1007/s12144-025-09027-9
Yang, F., & Yu, D. (2026) · Research Square · doi:10.21203/rs.3.rs-8894238/v1
Maxfield, M., Courtney, K., & Widom, C. S. (2026) · Alzheimer s & Dementia Behavior & Socioeconomics of Aging · doi:10.1002/bsa3.70088
Su, Z., Ma, Z., & Ma, J. (2026) · Journal of Youth and Adolescence · doi:10.1007/s10964-026-02393-y
Zhang, R., Jiang, C., Guan, Z., Sun, X., Caotian, G., & Teng, W. (2026) · BMC Geriatrics · doi:10.1186/s12877-026-08065-7
Pugh, E., Calle, M. T., Babulal, G. M., & Adkins‐Jackson, P. B. (2026) · Alzheimer s & Dementia · doi:10.1002/alz.71790
Pan, W., Wang, J., Wang, X., Zuo, Z., & Pan, W. (2026) · Electronic Commerce Research and Applications · doi:10.1016/j.elerap.2026.101645
- Authors
- Halahakoon, D. C., Lewis, G., & Roiser, J. P.
- Affiliations
- University College London (GB)
- Venue
- JAMA Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2019-03-01
- Volume
- 76
- Issue
- 3
- Pages
- 239
- ISSN
- 2168-622X (ISSN-L)
- OpenAlex
- W2906535216
- Cited by
- 50
- References
- 17
- Citations by year
- 2026: 11 · 2025: 7 · 2024: 6 · 2023: 11 · 2022: 5 · 2021: 3 · 2020: 4 · 2019: 3
- FWCI
- 1.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- Wellcome Trust (101798/Z/13/Z)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- cognitive impairment, depression, comorbidities, causal relationship, executive function
- MeSH terms
- Cognition, Depression, Depressive Disorder, Major, Major Depressive Disorder, Humans, Cognitive Dysfunction
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