Risks of Developing Persistent Opioid Use After Major Surgery
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3% of previously opioid-naïve patients continue to use opioids 3 months after major surgery.
“Moreover, 3% and 0.4% of previously opioid-naïve patients continue to use opioids 3 months7 and 1 year after major surgery, respectively, likely due to persistent postsurgical pain.6”
A significant proportion of chronic pain and problematic opioid use issues can be linked to the acute phase after major surgery, when patients are commonly prescribed opioid analgesics to manage their postsurgical pain.
“A significant proportion of chronic pain and problematic opioid use issues can be linked to the acute phase after major surgery, when patients are commonly prescribed opioid analgesics to manage their postsurgical pain.6,7”
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“significant proportion of chronic pain and problematic opioid use issues can be linked to the acute phase after major surgery, when patients are commonly prescribed opioid analgesics to manage their postsurgical pain.(6,7)”
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- Authors
- Soneji, N., Clarke, H. A., Ko, D. T., & Wijeysundera, D. N.
- Affiliations
- Toronto Western Hospital (CA)
- Institute for Clinical Evaluative Sciences (CA)
- St. Michael's Hospital (CA)
- Corresponding author
- Clarke, Hance A.
- Venue
- JAMA Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 2016-11-01
- Volume
- 151
- Issue
- 11
- Pages
- 1083
- ISSN
- 2168-6254 (ISSN-L)
- OpenAlex
- W2516647718
- Cited by
- 135
- References
- 6
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 7 · 2023: 7 · 2022: 16 · 2021: 19 · 2020: 28 · 2019: 18 · 2018: 12 · 2017: 12
- FWCI
- 13.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Surgery › Anesthesia and Pain Management
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- persistent opioid use, postoperative opioid use, major surgery, opioid use disorder, risk factors, postoperative pain management
- MeSH terms
- Aged, Analgesics, Opioid, Female, Humans, Male, Opioid-Related Disorders, Ontario, Pain, Postoperative, Postoperative Pain, Retrospective Studies, Risk
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