Cited by 699Bariatric Surgery and OutcomesBody Contouring and SurgeryMinimally Invasive Surgical Techniques

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Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study

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Courcoulas, Anita P., King, Wendy C., Belle, Steven H., Berk, Paul, Flum, David R., Garcia, Luis, Gourash, William, Horlick, Mary, Mitchell, James E., Pomp, Alfons, Pories, Walter J., Purnell, Jonathan Q., Singh, Ashima, Spaniolas, Konstantinos, Thirlby, Richard, Wolfe, Bruce M., Yanovski, Susan Z.·2018·JAMA Surgery

DOI 10.1001/jamasurg.2017.5025PMC PMC6584318

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Abstract

Importance: More information is needed about the durability of weight loss and health improvements after bariatric surgical procedures. Objective: To examine long-term weight change and health status following Roux-en-Y gastric bypass (RYGB) and laparoscopic adjustable gastric banding (LAGB). Design, Setting, and Participants: The Longitudinal Assessment of Bariatric Surgery (LABS) study is a multicenter observational cohort study at 10 US hospitals in 6 geographically diverse clinical centers. Adults undergoing bariatric surgical procedures as part of clinical care between 2006 and 2009 were recruited and followed up until January 31, 2015. Participants completed presurgery, 6-month, and annual research assessments for up to 7 years. Main Outcome and Measures: Percentage of weight change from baseline, diabetes, dyslipidemia, and hypertension, determined by physical measures, laboratory testing, and medication use. Results: Of 2348 participants, 1738 underwent RYGB (74%) and 610 underwent LAGB (26%). For RYBG, the median age was 45 years (range, 19-75 years), the median body mass index (calculated as weight in kilograms divided by height in meters squared) was 47 (range, 34-81), 1389 participants (80%) were women, and 257 participants (15%) were nonwhite. For LAGB, the median age was 48 years (range, 18-78), the body mass index was 44 (range, 33-87), 465 participants (76%) were women, and 63 participants (10%) were nonwhite. Follow-up weights were obtained in 1300 of 1569 (83%) eligible for a year-7 visit. Seven years following RYGB, mean weight loss was 38.2 kg (95% CI, 36.9-39.5), or 28.4% (95% CI, 27.6-29.2) of baseline weight; between years 3 and 7 mean weight regain was 3.9% (95% CI, 3.4-4.4) of baseline weight. Seven years after LAGB, mean weight loss was 18.8 kg (95% CI, 16.3-21.3) or 14.9% (95% CI, 13.1-16.7), with 1.4% (95% CI, 0.4-2.4) regain. Six distinct weight change trajectory patterns for RYGB and 7 for LAGB were identified. Most participants followed trajectories in which weight regain from 3 to 7 years was small relative to year-3 weight loss, but patterns were variable. Compared with baseline, dyslipidemia prevalence was lower 7 years following both procedures; diabetes and hypertension prevalence were lower following RYGB only. Among those with diabetes at baseline (488 of 1723 with RYGB [28%]; 175 of 604 with LAGB [29%]), the proportion in remission at 1, 3, 5, and 7 years were 71.2% (95% CI, 67.0-75.4), 69.4% (95% CI, 65.0-73.8), 64.6% (95% CI, 60.0-69.2), and 60.2% (95% CI, 54.7-65.6), respectively, for RYGB and 30.7% (95% CI, 22.8-38.7), 29.3% (95% CI, 21.6-37.1), 29.2% (95% CI, 21.0-37.4), and 20.3% (95% CI, 9.7-30.9) for LAGB. The incidence of diabetes at all follow-up assessments was less than 1.5% for RYGB. Bariatric reoperations occurred in 14 RYGB and 160 LAGB participants. Conclusions and Relevance: Following bariatric surgery, different weight loss patterns were observed, but most participants maintained much of their weight loss with variable fluctuations over the long term. There was some decline in diabetes remission over time, but the incidence of new cases is low following RYGB. Trial Registration: clinicaltrials.gov Identifier: NCT00465829.

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Neighborhood deprivation and residential property values do not affect weight loss at 1 or 3 years after bariatric surgery
Drewnowski, A., Hong, B. D., Shen, E., Ji, M., Paz, S. R., Bhakta, B. B., Macias, M. M., Crawford, C. L., Lewis, K. H., Liu, J., et al. (2023) · Obesity · doi:10.1002/oby.23623 · Cited by 9
“Some college or college degree 0.20 ( 1.50 to 1.11) 0.77 0.59 ( 0.92 to 2.11) 0.44 Some graduate school or graduate degree 0.50 ( 1.22 to 2.22) 0.57 0.59 ( 1.40 to 2.59) 0.56 Not reported (missing) 0.97 ( 4.20 to 2.26) 0.56 1.04 ( 4.82 to 2.74) 0.59 Self-reported annual income <$50,000 — — ≥$51,000 1.13 ( 2.18 to 0.07…”
BackgroundInfluential
Psychological and Behavioral Aspects of Primary and Reoperative Surgery: a 6-Month Longitudinal Study
Pinto‐Bastos, A., Conceição, E., de Lourdes, M., Arrojado, F., Brandão, I., & Machado, P. P. P. (2018) · Obesity Surgery · doi:10.1007/s11695-018-3452-0 · Cited by 9
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“9% WR between 3 and 7 years post RYGB [22].”
BackgroundInfluential
Comparative efficacy of remotely delivered mindfulness-based eating awareness training versus behavioral-weight loss counseling during COVID-19
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Axer, S. S., Szabó, É., & Näslund, I. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06783-0 · Cited by 9
“demonstrated an association between the “magnitude and direction/slope of the initial loss” and long-term weight trajectories, stressing the importance of “enhanced and early (Years 1-2) postoperative efforts to optimize short-term weight loss trajectory directions” [30].”
Background
Distinctive patterns of sulfide- and butyrate-metabolizing bacteria after bariatric surgery: potential implications for colorectal cancer risk
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“Our post-surgery adults were recruited more than six months after RYGB or VSG to assess their effects on the microbiome in the weight-maintenance phase and after resuming solid foods.(37,38) We excluded patients if they had other risk factors for colorectal cancer (e.”
Method
Metabolic surgery results in greater metabolic benefits in patients who achieve healthy weight
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“Studies have shown that a significant proportion of patients, ranging from 3.9% to 87%, experience recurrent weight gain within 2–6 years following metabolic bariatric procedures, such as sleeve gastrectomy and Roux-en-Y gastric bypass[6–9].”
Influential
Opportunities for General Internal Medicine to Promote Equity in Obesity Care
Kane, R. M., Nicklas, J. M., Schwartz, J. L., Bramante, C. T., Yancy, W. S., Gudzune, K. A., & Jay, M. R. (2024) · Journal of General Internal Medicine · doi:10.1007/s11606-024-09084-z · Cited by 8
“45,93,94 Guidelines recommend surgery for patients with BMI ≥ 35 kg/m 2 or ≥ 30 kg/m 2 with a weight-related comorbidity.”
Obesity and mitochondrial uncoupling – an opportunity for the carbon monoxide-based pharmacology of metabolic diseases
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Mediators of suicidality 12 years after bariatric surgery relative to a nonsurgery comparison group
Mabey, J. G., Kolotkin, R. L., Crosby, R. D., Crowell, S. E., Hunt, S. C., & Davidson, L. E. (2020) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2020.08.026 · Cited by 9
“Weight regain following peak weight loss in bariatric surgery is a welldocumented phenomenon (42) and may be related to the recurrence of the chronic metabolic conditions that coexist with severe obesity (43).”
Background
The impact of psychological distress on weight regain in post-bariatric patients during the COVID-19 pandemic: A latent profile analysis
Salituro, N., Landi, G., Garelli, S., Balsamo, F., Rottoli, M., Cattivelli, R., Tossani, E., Grandi, S., Pagotto, U., Bernante, P., et al. (2022) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2022.111144 · Cited by 8
Examining spousal and family support as predictors of long-term weight loss and remission of type 2 diabetes following bariatric surgery in Singapore: a retrospective cohort study
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The ‘Behavioral Balance Model’: A new perspective on the aetiology and therapy of obesity
Schultes, B., Ernst, B., Hallschmid, M., Bueter, M., & Meyhöfer, S. M. (2023) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15271 · Cited by 9
“77,78 While the experience of weight regain can be frustrating, it also underlines that behavioural support strengthening top-down control can be still necessary after bariatric surgery and supports the idea of a multimodal treatment approach.”
Background
Osteoarthritis in patients with obesity: The bariatric surgery impacts on its evolution
Eymard, F., & Aron‐Wisnewsky, J. (2023) · Joint Bone Spine · doi:10.1016/j.jbspin.2023.105639 · Cited by 9
Portal Venous Metabolite Profiling After RYGB in Male Rats Highlights Changes in Gut-Liver Axis
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“One of the most remarkable features of Roux-en-Y gastric bypass surgery (RYGB) that makes it a superior therapy to other interventions is its ability to elicit clinically significant weight loss that is sustained over long periods of time [1, 2].”
Background
Clinical and Metabolic Improvement after Bariatric Surgery in Older Adults: A 6-Year Follow-Up
da Cunha, J. B., Fialho, M. C. P., Arruda, S., Nóbrega, O. D. T., & Camargos, E. F. (2020) · The journal of nutrition health & aging · doi:10.1007/s12603-020-1406-4 · Cited by 8
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Eating patterns and unhealthy weight control behaviors are associated with loss-of-control eating following bariatric surgery
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24‐Month f ollow‐up of randomized controlled trial of g uided‐self‐help for l oss‐of‐control eating after bariatric surgery
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“2 diabetes mellitus (DM) remission (5,6).”
Influential
Long-term Engagement in Physical Activity Among Bariatric Surgery Patients: Associations with Treatment Outcomes at 5-Year Follow-up
Launius, K. N., Neff, K. M. H., Schuh, L. M., Saules, K. K., Creel, D. B., & Inman, M. M. (2022) · Obesity Surgery · doi:10.1007/s11695-022-06425-x · Cited by 8
“1 3 recurrence is common, often not starting until around 2 years post-surgery [13], studying the role of PA over the course of many years is warranted.”
Background
Remission with an Intervention
Hanipah, Z. N., Rubino, F., & Schauer, P. R. (2023) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2022.09.002 · Cited by 8
The Influence of a Roux-en-Y Gastric Bypass on Plasma Concentrations of Antidepressants
Garin, P., Favre, L., Vionnet, N., Frantz, J., Eap, C. B., & Vandenberghe, F. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06526-1 · Cited by 8
“The prevalence of depression decreases during the first 6 months, when an important degree of weight loss is observed, but rises again 2 to 3 years after intervention, when weight loss is plateauing [32].”
Background
Conversion of laparoscopic sleeve gastrectomy after weight loss failure into laparoscopic one anastomosis gastric bypass: short-term safety and efficacy and effect of indications on outcome
Gerges, W. B., Omran, H., & Makram, F. (2021) · Surgical Endoscopy · doi:10.1007/s00464-021-08374-5 · Cited by 8
Financial Incentives to Improve Patient Follow-up and Weight Loss After Bariatric Surgery
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Increased Resting Energy Expenditure/Body Weight and Decreased Respiratory Quotient Correlate with Satisfactory Weight Loss After Sleeve Gastrectomy: a 6-Month Follow-Up
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The Impact of Reoperations Following Bariatric Surgery on Mid-term Outcomes
Straatman, J., Demirkiran, A., Harlaar, N. J., Cense, H. A., Dutch Audit for Treatment of Obesity Group (DATO), & Jonker, F. H. W. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06519-0 · Cited by 7
“The effect of major complications following primary surgery, such as reoperations within 30 days of index surgery, on mid-to-long-term outcomes, was not discussed in larger follow-up cohort series [8, 9].”
BackgroundInfluential
Obesity-associated Inflammation and Alloimmunity
Zhou, H., Gizlenci, M., Xiao, Y., Martin, F., Nakamori, K., Zicari, E. M., Sato, Y., & Tullius, S. G. (2024) · Transplantation · doi:10.1097/tp.0000000000005183 · Cited by 8
“123 124-127 In recent years, metabolomic analysis has emerged as a powerful tool in metabolic and bariatric research.”
Disordered Eating Behaviors and Weight Regain in Post-Bariatric Patients
Lopes, K. G., Romagna, E. C., Mattos, D. M. F., & Kraemer‐Aguiar, L. G. (2024) · Nutrients · doi:10.3390/nu16234250 · Cited by 10
“Bariatric surgery is an effective and sustained treatment for severe obesity [2], improving or remitting chronic diseases and reducing mortality [3].”
Glycemia, Insulin Sensitivity, and Secretion Improve 3 Months Post-sleeve Gastrectomy in Youth With Type 2 Diabetes
Dobbs, T. J., Cree‐Green, M., Bailey, A., Baumgartner, A., Garrish, J., Diniz-Behn, C., Pyle, L., Kelsey, M. M., SHAH, A. S., Inge, T. H., et al. (2025) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaf020 · Cited by 7
“MBS results in significant and durable weight loss of nearly 30% after 7 years in adults [14], with short-and medium-term metabolic effects that appear independent of weight loss, including improvements in glycemia, hypertension, and hyperlipidemia [15] and diabetes remission in most adults [16].”
Psychological Assessment and Psychosocial Outcomes in Bariatric Surgery Candidates: A Retrospective Study
Magurano, M. R., Napolitano, D., Bozzetti, M., Cascio, A. L., Oppo, L., Tayupanta, L. A. F., Ferrazzoli, S., Lopasso, L., Rellini, E., Raffaelli, M., et al. (2025) · Healthcare · doi:10.3390/healthcare13111294 · Cited by 8
“While lifestyle modifications and pharmacotherapy are considered primary interventions, bariatric surgery has emerged as the most effective treatment for long-term weight reduction and improvement of obesity-related comorbidities [4,5].”
Physiology of the Weight-Reduced State and Its Impact on Weight Regain
Hafida, S., & Apovian, C. M. (2022) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2022.06.002 · Cited by 7
Transcriptome Changes and Metabolic Outcomes After Bariatric Surgery in Adults With Obesity and Type 2 Diabetes
Rashid, M., Qarni, A. A. A., Mahri, S. A., Mohammad, S., Khan, A. H., Abdullah, M. L., Lehé, C. L., Amoudi, R. A., Aldibasi, O. S., & Bouchama, A. (2023) · Journal of the Endocrine Society · doi:10.1210/jendso/bvad159 · Cited by 7
“Furthermore, the proportion of patients in remission can decline after several years of follow-up, although the rate varies between studies [ 3, 4].”
BackgroundResult
Bariatric surgery and its role in obesity pandemic
Lo, T., & Tavakkoli, A. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.09.002 · Cited by 7
Comparison of Ambulatory Health Care Costs and Use Associated With Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy
Lewis, K. H., Argetsinger, S., Arterburn, D. E., Clemenzi, J., Zhang, F., Kamusiime, R., Fernandez, A., Ross‐Degnan, D., & Wharam, J. F. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.9661 · Cited by 7
Long-Term Outcomes of Bariatric Surgery in Idiopathic Intracranial Hypertension Patients
Hermes, S. M., Bharadwaj, M., Miller, N. R., Waslo, C. S., Husain, F. A., Wolfe, B. M., & Tanne, E. (2022) · The Neurologist · doi:10.1097/nrl.0000000000000446 · Cited by 7
Self-citation
Cohort profile: The Bariatric Experience Long Term (BELONG): a long-term prospective study to understand the psychosocial, environmental, health and behavioural predictors of weight loss and regain in patients who have bariatric surgery
Coleman, K. J., Paz, S. R., Bhakta, B. B., Taylor, B., Liu, J., Yoon, T. K., Macias, M. M., Arterburn, D. E., Crawford, C. L., Drewnowksi, A., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-059611 · Cited by 7
Changes in Marital Status Following Roux-en-Y Gastric Bypass and Sleeve Gastrectomy: A US Multicenter Prospective Cohort Study
King, W. C., Hinerman, A. S., & White, G. E. (2022) · Annals of Surgery Open · doi:10.1097/as9.0000000000000182 · Cited by 7
Self-citation
A Positive Emotion–Focused Intervention to Increase Physical Activity After Bariatric Surgery: Protocol for a Pilot Randomized Controlled Trial
Feig, E. H., Harnedy, L. E., Thorndike, A. N., Psaros, C., Healy, B. C., & Huffman, J. C. (2022) · JMIR Research Protocols · doi:10.2196/39856 · Cited by 7
Twelve-Month Outcomes in Patients with Obesity Following Bariatric Surgery—A Single Centre Experience
Soroceanu, R. P., Timofte, D. V., Maxim, M., Platon, R., Vlăsceanu, V. I., Ciuntu, B. M., Pînzariu, A. C., Clim, A., Soroceanu, A., Silistraru, I., et al. (2023) · Nutrients · doi:10.3390/nu15051134 · Cited by 9
Limited Effect of Beta-blockade on Postoperative Outcome After Laparoscopic Gastric Bypass Surgery
Stenberg, E., Mohseni, S., Cao, Y., & Näslund, E. B. (2019) · Obesity Surgery · doi:10.1007/s11695-019-04108-8 · Cited by 7
Differential Outcomes and Clinical Challenges of NAFLD With Extreme Obesity
Arnouk, J., Rachakonda, V. P., Jaiyeola, D., & Behari, J. (2020) · Hepatology Communications · doi:10.1002/hep4.1572 · Cited by 7
“(24-26) Furthermore, bariatric surgery may not confer equal weight-reduction benefit in all patients and may increase mortality in some subgroups.(27,28) Finally, it is possible that in individuals with extreme obesity, weight-loss surgery may be less beneficial than in lower BMI individuals.”
Background
The effect of Roux-en-Y gastric bypass in the treatment of hypertension and diabetes
Marchetti, G., Ardengh, A. O., Colombo‐Souza, P., Kassab, P., de Freitas, W. R., & Ilias, E. J. (2020) · Revista do Colégio Brasileiro de Cirurgiões · doi:10.1590/0100-6991e-20202655 · Cited by 9
The Cards and Lottery Task: Validation of a New Paradigm Assessing Decision Making Under Risk in Individuals With Severe Obesity
Schäfer, L., Schmidt, R., Müller, S. M., Dietrich, A., & Hilbert, A. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00690 · Cited by 7
“In contrast, surgical weight-loss interventions produce substantial weight loss (7), although long-term effects (>5 years) are variable across patients and weight regain is likely to set in again (8, 9), particularly in those with a pre-surgery BMI ≥ 40 kg/m2 (10).”
Background
Actual weight loss trajectories after bariatric surgery compared with the SOPHIA prediction tool: An observational comparison study
Sankar, A., McNeilage, C., Alkhaffaf, B. H., & Syed, A. A. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16219 · Cited by 6
“17,18 However, the converse has also been found, and much of the existing literature has a female population bias.”
Long-term Satisfaction with Roux-en-Y Gastric Bypass Surgery
White, G. E., Courcoulas, A. P., & King, W. C. (2020) · Annals of Surgery · doi:10.1097/sla.0000000000004625 · Cited by 6
“4% weight loss at 7 years post-RYGB.(2) Our findings also suggest that acceptable weight may be an unrealistic weight loss goal since the median percent weight loss needed to reach acceptable weight (37.”
BackgroundInfluentialSelf-citation
Addressing a critical need: A randomised controlled feasibility trial of acceptance and commitment therapy for bariatric surgery patients at 15–18 months post-surgery
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GLP-1 and GIP may play a role in long-term weight trajectories after gastric bypass
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Comparative long-term effectiveness and safety of primary bariatric surgeries in treating type 2 diabetes mellitus in adults: a protocol for systematic review and network meta-analysis of randomised controlled trials
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Conversion from Prediabetes to Diabetes in Individuals with Obesity, 5-Years Post-Band, Sleeve, and Gastric Bypass Surgeries
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Bariatric Surgery Among Medicare Subgroups: Short‐ and Long‐Term Outcomes
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“The primary strength of this study is the availability of long-term follow-up with high retention (31).”
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Body mass index and attitudes towards health behaviors among women with endometrial cancer before and after treatment
Harrison, R. F., Zhao, H., Sun, C. C., Fu, S., Armbruster, S. D., Westin, S. N., Rauh‐Hain, J. A., Lu, K. H., Giordano, S. H., & Meyer, L. A. (2019) · International Journal of Gynecological Cancer · doi:10.1136/ijgc-2019-000999 · Cited by 6
Optimizing contraceptive access for women undergoing bariatric surgery
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Preoperative Depression Status and 5 Year Metabolic and Bariatric Surgery Outcomes in the PCORnet Bariatric Study Cohort
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Influence of Bariatric Surgery on Oral Microbiota: A Systematic Review
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Marijuana, e-cigarette, and tobacco product use in young adults who underwent pediatric bariatric surgery
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“Blood pressure reductions are seen following RYGB surgery and seem to be correlated to the magnitude of weight loss [27,53].”
BackgroundMethodInfluential
Role of Ethnicity on Weight Loss and Attrition After Bariatric Surgery
King, R. A., Patel, K., Mark, V., Shah, A. M., & Laferrère, B. (2019) · Obesity Surgery · doi:10.1007/s11695-019-04029-6 · Cited by 6
Psychometric properties of the eating loss of control scale among postbariatric patients
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Halo or horn? A qualitative study of mothers’ experiences with feeding children during the first year following bariatric surgery
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Self-citation
Weight loss after bariatric surgery in cancer survivors
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Altered systematic glucose utilization after gastrectomy: correlation with weight loss
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Anthropometrics by Three-Dimensional Photonic Scanner in Patients with Obesity Before and After Bariatric Surgery
Shah, A. M., PRASAD, M. A., Devjani, S., Rai, P., Ashby‐Thompson, M., Yu, W. W., Gallagher, D., & Laferrère, B. (2020) · Obesity Surgery · doi:10.1007/s11695-020-04905-6 · Cited by 6
“Further, minority populations are often under-represented in bariatric cohorts [18, 19] and less likely to get bariatric surgery compared with their Caucasian counterparts [20].”
Background
The Bariatric Interprofessional Psychosocial Assessment of Suitability Scale predicts binge eating, quality of life and weight regain following bariatric surgery
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Effects of Bariatric Surgery on Influenza-Like Illness: a Two-Center Cross-sectional Study
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“excluded (a) patients ≤ 18-year-old at the time of the survey; (b) subjects that had undergone a bariatric procedure other than adjustable gastric band (AGB), sleeve gastrectomy (SG), and Roux-en-Y Gastric By-pass (RYGB); (c) subjects that had undergone the intervention less than 12 months before the beginning of the…”
Background
Preoperative brain μ-opioid receptor availability predicts weight development following bariatric surgery in women
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“Weight regain following bariatric surgery occurs in one-fifth (15–17) up to one-third of the patients (18–20).”
BackgroundInfluential
Psychological Functioning and Health Behaviors Associated with Weight Loss Patterns up to 13.7 Years After Weight Loss Surgery
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Post-bariatric Surgery Outcomes and Complications in Patients with Celiac Disease: a Matched Case-Control Study
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Associations of Pregnancy After Bariatric Surgery with Long‐Term Weight Trajectories and Birth Weight: LABS‐2 Study
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Seeking an Initial-Weight-Independent Metric in a Mediterranean Cohort of Gastric Bypass Patients: the %AWL Revisited
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Relations between trajectories of weight loss and changes in psychological health over a period of 2 years following bariatric metabolic surgery
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Clinical Significance of Early Postoperative Weight Loss in Bariatric Surgery: A Narrative Review
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“Understanding these mechanisms is critical, as they form the biological basis for early weight loss and may inform the plan to optimize surgical outcomes and enhance postoperative management [9,49-51].”
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Self-citation
A reincidência de obesidade em pacientes que realizaram cirurgia bariátrica: uma revisão de literatura
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Psychological Traits of Bariatric Surgery Candidates and Predictors of Outcomes
Hadipour, A. L., Mento, C., Scaramuzzino, C., Arena, F., Turiaco, F., Muscatello, M. R. A., Navarra, G., Pandolfo, G., & Lombardo, C. (2025) · Journal of Personalized Medicine · doi:10.3390/jpm15060215 · Cited by 5
“However, although short-term outcomes are generally favourable, these results should be interpreted cautiously in light of possible surgical risks and the growing evidence of suboptimal long-term efficacy for a substantial proportion of patients [23,24].”
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“Overall, the trends of individual ADM deescalation are consistent with a previous study in the 12 months following BS that showed proportional decreases in each type of ADM.(5) However, we identified a small increase in metformin, sulfonylurea, and insulin from 12 months after BS, which may be due to worsening blood g…”
BackgroundMethodResultInfluential
Additional Metabolic Effects of Bariatric Surgery in Patients with a Poor Mid-Term Weight Loss Response: A 5-Year Follow-Up Study
Benaiges, D., Bisbe, M., Pedro‐Botet, J., de Vargas‐Machuca, A., Ramón, J. M., Pera, M., Villatoro, M., Fontané, L., Julià, H., Climent, E., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9103193 · Cited by 5
“They are more frequently identified at mid-term follow-up taking into account that most patients experience a slight weight regain from the first year post-surgery [3,7,8].”
BackgroundResult
Real-world retrospective analysis of outcomes in patients undergoing bariatric surgery with class 1 obesity
Altieri, M. S., DeMaria, E. J., Lensing, C. J., Derecho, J., Fallorina, R., Mehrotra, S., Pories, W. J., & Irish, W. D. (2022) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2022.01.011 · Cited by 5
Self-citation
Bariatric Surgery and Risk of Unemployment and Sickness Absence
Bramming, M., Becker, U., Jørgensen, M. B., Neermark, S., Bisgaard, T., & Tolstrup, J. S. (2022) · Obesity Surgery · doi:10.1007/s11695-021-05802-2 · Cited by 4
Metabolic Profile and Metabolite Analyses in Extreme Weight Responders to Gastric Bypass Surgery
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Early-phase insulin hypersecretion associated with weight loss outcome after LSG: a prospective cohort study in Asian patients with BMI ≥28 kg/m2
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Bariatric emergencies for the general surgeon
Altieri, M. S., Rogers, A. M., Afaneh, C. I., Moustarah, F., Grover, B. T., Khorgami, Z., & Eisenberg, D. (2023) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2023.02.007 · Cited by 7
Longitudinal study
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Longer-Term Weight Loss Outcomes Are Not Primarily Driven by Diet Following Roux-en-Y Gastric Bypass and Sleeve Gastrectomy
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“The variability of longer-term (beyond the first year) weight loss outcomes after surgery is well documented and can depend on numerous factors, including the age of the patient undergoing surgery [27]; the initial surgery type and subsequent surgical revisions or reversals [28]; sedentary behavior and physical activi…”
Background
Does the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program bariatric risk/benefit calculator hold its weight? An assessment of its accuracy
Giannopoulos, S., Athanasiadis, D. I., Hernandez, E., Colgate, C. L., Christodoulides, A., Osuji, V. C., Petrucciani, A., & Stefanidis, D. (2023) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2023.10.019 · Cited by 5
Six-year postoperative associations between the Minnesota Multiphasic Personality Inventory – 3 (MMPI-3) and weight recurrence, eating behaviors, adherence, alcohol misuse, and quality of life
Marek, R. J., Ben‐Porath, Y. S., & Heinberg, L. J. (2023) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2023.12.008 · Cited by 7
Pre-Surgery Cortisol Levels as Biomarker of Evolution after Bariatric Surgery: Weight Loss and Weight Regain
Casteràs, A., Fidilio, E., Comas, M., Zabalegui, A., Flores, V., Giralt, M., Troyano, N. D., Ferrer, R., Vilallonga, R., Ciudin, A., et al. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13175146 · Cited by 7
“…inverse correlation between morning serum cortisol at baseline and the degree reduction 6 months postoperative, but the di ﬀ erence at 12 months disappeared, losing clinical relevance. female) who had undergone SG, a was associated to less probability of achieving %EWL ≥ 50% at 6 months after BS.”
Background
Update on eating disorders and disordered eating behaviors in metabolic bariatric surgery patients
Conceição, E., Mitchell, J. E., & Sarwer, D. B. (2024) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000962 · Cited by 5
Self-citation
A Naturalistic Assessment of the Relationship between Negative Affect and Loss of Control Eating Over Time Following Metabolic and Bariatric Surgery
Kerver, G. A., Wonderlich, J. A., Laam, L. A., Amponsah, T., Nameth, K., Steffen, K., Heinberg, L. J., Safer, D., Wonderlich, S. A., & Engel, S. (2024) · Appetite · doi:10.1016/j.appet.2024.107748 · Cited by 6
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Changes in visual attention towards food cues after obesity surgery: An eye-tracking study
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Benefits of Adjuvant Medical Weight Loss Intervention in Setting of Weight Regain and Inadequate Weight Loss After Weight Loss Surgery
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“Furthermore, weight regain has been shown to begin 1-3 years after bariatric surgery and continue over time with most weight regain seen between years 2 or 3 and years 7 or 8.(1,8) Similarly, patient weight after MBS in the adolescent population appears to nadir around 1 year after surgery with relative increases in w…”
Background
Relationship among Self-Efficacy Expectations, Locus of Control, and Attributions in Bariatric Patients
Ugarte, C. A., Quiñones, Á., & Saúl, L. Á. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19127107 · Cited by 6
“Bariatric surgery is the most effective treatment for obesity [1,2].”
Background
Maternal and Neonatal Outcomes of Pregnancy within 7 years after Roux-Y Gastric Bypass or Sleeve Gastrectomy Surgery
White, G. E., Courcoulas, A. P., Broskey, N. T., Rogan, S. C., Jeyabalan, A., & King, W. C. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06575-6 · Cited by 5
“Micronutrient absorption is most hampered during rapid weight loss [7], which generally occurs in the first 6–12 months after MBS [8].”
BackgroundSelf-citation

Authors: Courcoulas, A. P., King, W. C., Belle, S. H., Berk, P., Flum, D. R., Garcia, L., Gourash, W., Horlick, M., Mitchell, J. E., Pomp, A., Pories, W. J., Purnell, J. Q., Singh, A., Spaniolas, K., Thirlby, R., Wolfe, B. M., & Yanovski, S. Z.
Affiliations: University of Pittsburgh Medical Center (US)
University of Pittsburgh (US)
Columbia University (US)
University of Washington (US)
University of North Dakota (US)
National Institute of Diabetes and Digestive and Kidney Diseases (US)
Neuropsychiatric Research Institute (US)
Weill Cornell Medicine (US)
East Carolina University (US)
Oregon Health & Science University (US)
Corresponding author: Courcoulas, Anita P.
ORCID: Courcoulas, Anita P.
King, Wendy C.
Flum, David R.
Gourash, William
Mitchell, James E.
Pomp, Alfons
Pories, Walter J.
Purnell, Jonathan Q.
Singh, Ashima
Spaniolas, Konstantinos
Wolfe, Bruce M.
Venue: JAMA Surgery
Publisher: American Medical Association (AMA)
Published: 2018-05-01
Volume: 153
Issue: 5
Pages: 427
ISSN: 2168-6254 (ISSN-L)
DOI: 10.1001/jamasurg.2017.5025
PMC: PMC6584318
OpenAlex: W2771736595
Cited by: 699
References: 18
Citations by year: 2026: 63 · 2025: 70 · 2024: 77 · 2023: 92 · 2022: 93 · 2021: 102 · 2020: 97 · 2019: 69 · 2018: 35
FWCI: 56.28
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: JAMA Surgery (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (U01DK066471, U01DK066557, U01DK066526, U01DK066568, U01DK108320, U01DK066667, U01DK066585)
National Center for Research Resources (UL1RR024153, M01RR000037, UL1RR024996)
Topics: Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
Health Sciences › Medicine › Surgery › Body Contouring and Surgery
Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
Keywords: bariatric surgery, Roux-en-Y gastric bypass, laparoscopic adjustable gastric banding, weight loss, weight regain, diabetes remission, dyslipidemia, hypertension, obesity, metabolic surgery outcomes, body mass index
MeSH terms: Body-Weight Trajectory, Adult, Aged, Female, Follow-Up Studies, Health Status, Humans, Male, Middle Aged, Obesity, Morbid, Retrospective Studies, Time Factors, Weight Loss, Body Mass Index, Treatment Outcome, Bariatric Surgery, Young Adult

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Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study

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