Connectional networks within the orbital and medial prefrontal cortex of macaque monkeys

In the citing paper

“Based on local cortico-cortical connections, two connectional systems or networks were recognized within the OMPFC, which have been referred to as the 'orbital' and 'medial prefrontal networks'.”

In the citing paper

“It consists of areas on the ventromedial surface of the frontal cortex, rostral and ventral to the genu, areas along the medial edge of the orbital cortex, and a small caudolateral orbital region at the rostral end of the insula (Carmichael and Price, 1996; Figure 3).”

In the citing paper

“As this region receives connections from all exteroceptive (Barbas, 2000) and interoceptive modalities (Carmichael and Price, 1996), it has been viewed as a polymodal convergence zone (Rolls, 2000), supporting the integration of external and internal stimuli with judgements about their affective relevance to the self (Ochsner and Gross, 2005).”

In the citing paper

“Second, tract tracing studies in the monkey demonstrated the existence of many of the structural connections implied by the first option described above, including direct (and largely reciprocal) connections from AIC, ACC and SGC to medial prefrontal pole (area 10 m; Carmichael and Price, 1996).”

In the citing paper

“Efferent projections from rat IL are similar to those of monkey 25, whereas the efferent projections from rat PrL are similar to those of monkey 32 (33–39).”

In the citing paper

“Since primate vmPFC exhibits a significant pattern of posterior to anterior projections (34)”

In the citing paper

“there remain significant restrictions on the extent to which one can draw inferences from what is known about the neural mechanisms by which rat IL comes to extinguish conditioned fear to claims about the neural mechanisms by which primate vmPFC comes to extinguish conditioned fear; especially since a number of anatomical studies make clear that areas such as 10m and 10r share little connectional”