Cited by 68Nutrition and Health in AgingClinical Nutrition and GastroenterologyNutrition and Health Studies

Protein and energy supplementation in elderly people at risk from malnutrition

Milne, AC, Potter, J, Avenell, A·2002·Cochrane Database of Systematic Reviews

Abstract

Background This review was carried out because evidence for the effectiveness of nutritional supplements containing protein and energy which are often prescribed for elderly people is limited. Furthermore malnutrition is more common in this age group and deterioration of nutritional status can occur during a stay in hospital. It is important to establish whether supplementing the diet with protein and energy is an effective way of improving outcomes for older people at risk from malnutrition. Objectives This review examines the evidence from trials for improvement in nutritional status and clinical outcomes when extra protein and energy food were provided, usually in the form of commercial 'sip-feeds'. Search strategy We searched The Cochrane Library (issue 1, 2001), MEDLINE (1966 to February 2001), EMBASE (1980 to March 2001), Health star (1975 to March 2001), CINAHL (1982 to Jan 2001), BIOSIS (1985 to March 2001) and CAB abstracts (1973 to March 2001). We also hand searched nutrition journals and reference lists and contacted 'sip-feed' manufacturers. Date of most recent search: March 2001. Selection criteria Randomised controlled trials and quasi-randomised controlled trials of oral protein and energy supplementation in older people with the exception of groups recovering from cancer treatment or in critical care. Data collection and analysis Two reviewers independently assessed trials prior to inclusion and independently extracted data and assessed trial quality; any diff…

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Crossref · 10.1002/14651858.cd003288

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  • Subgroup analysis in meta-analyses from Milne et al. 2002 and 2005 showed a consistently statistically significant impact of ONS on mortality when supplementation was continued for 35 days or more compared to less than 35 days.

    “Regarding the length of the intervention, subgroup analysis in the meta-analyses from Milne et al. from 2002 (117) and 2005 (118) showed a consistently statistically significant impact of ONS on mortality when supplementation was continued for 35 days or more compared to less than 35 days.”
  • A systematic literature search found six high-quality SLRs that have assessed the efficacy of ONS versus usual care in older persons.

    “A systematic literature search found six high-quality SLRs that have assessed the efficacy of ONS versus usual care in older persons (114-121).”

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Authors
Milne, A., Potter, J., & Avenell, A.
Affiliations
University of Aberdeen (GB)
Venue
Cochrane Database of Systematic Reviews
Published
2002-04-22
Issue
3
Pages
CD003288-CD003288
ISSN
  • 1361-6137 (ISSN-L)
  • 1465-1858
OpenAlex
W4243995816
Cited by
68
References
0
Citations by year
2026: 1 · 2025: 1 · 2024: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 1 · 2015: 5 · 2014: 2 · 2013: 2
Type
reference entry
Language
en
Open access
closed
Locations
  • Cochrane Database of Systematic Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
Keywords
dietary supplements, malnutrition, older adults, nutritional status, mortality, hospital-acquired malnutrition, functional outcome, complications, nursing homes, energy supplementation, hospital readmission, length of hospital stay, hospital costs, in-hospital complications, hospital discharge outcomes
MeSH terms
Aged, Energy Intake, Dietary Proteins, Humans, Length of Stay, Nutrition Disorders, Randomized Controlled Trials as Topic

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