Cited by 221Rheumatoid Arthritis Research and TherapiesMusculoskeletal pain and rehabilitationCancer survivorship and care

The DOI matches its Crossref record; 105 of the 106 references it cites were found in a registry or an index.

Non-pharmacological interventions for fatigue in rheumatoid arthritis

Open access

Cramp, Fiona, Hewlett, Sarah, Almeida, Celia, Kirwan, John R, Choy, Ernest HS, Chalder, Trudie, Pollock, Jon, Christensen, Robin·2013·Cochrane Database of Systematic Reviews

DOI 10.1002/14651858.cd008322.pub2PMC PMC11748118

Open this paper in CoChat — free account

Abstract

BACKGROUND: Fatigue is a common and potentially distressing symptom for people with rheumatoid arthritis with no accepted evidence based management guidelines. Non-pharmacological interventions, such as physical activity and psychosocial interventions, have been shown to help people with a range of other long-term conditions to manage subjective fatigue. OBJECTIVES: To evaluate the benefit and harm of non-pharmacological interventions for the management of fatigue in people with rheumatoid arthritis. This included any intervention that was not classified as pharmacological in accordance with European Union (EU) Directive 2001/83/EEC. SEARCH METHODS: The following electronic databases were searched up to October 2012, Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE; EMBASE; AMED; CINAHL; PsycINFO; Social Science Citation Index; Web of Science; Dissertation Abstracts International; Current Controlled Trials Register; The National Research Register Archive; The UKCRN Portfolio Database. In addition, reference lists of articles identified for inclusion were checked for additional studies and key authors were contacted. SELECTION CRITERIA: Randomised controlled trials were included if they evaluated a non-pharmacological intervention in people with rheumatoid arthritis with self-reported fatigue as an outcome measure. DATA COLLECTION AND ANALYSIS: Two review authors selected relevant trials, assessed risk of bias and extracted data. Where appropriate, data were pooled using meta-analysis with a random-effects model. MAIN RESULTS: Twenty-four studies met the inclusion criteria, with a total of 2882 participants with rheumatoid arthritis. Included studies investigated physical activity interventions (n = 6 studies; 388 participants), psychosocial interventions (n = 13 studies; 1579 participants), herbal medicine (n = 1 study; 58 participants), omega-3 fatty acid supplementation (n = 1 study; 81 participants), Mediterranean diet (n = 1 study; 51 participants), reflexology (n = 1 study; 11 participants) and the provision of Health Tracker information (n = 1 study; 714 participants). Physical activity was statistically significantly more effective than the control at the end of the intervention period (standardized mean difference (SMD) -0.36, 95% confidence interval (CI) -0.62 to -0.10; back translated to mean difference of 14.4 points lower, 95% CI -4.0 to -24.8 on a 100 point scale where a lower score means less fatigue; number needed to treat for an additional beneficial outcome (NNTB) 7, 95% CI 4 to 26) demonstrating a small beneficial effect upon fatigue. Psychosocial intervention was statistically significantly more effective than the control at the end of the intervention period (SMD -0.24, 95% CI -0.40 to -0.07; back translated to mean difference of 9.6 points lower, 95% CI -2.8 to -16.0 on a 100 point scale, lower score means less fatigue; NNTB 10, 95% CI 6 to 33) demonstrating a small beneficial effect upon fatigue. For the remaining interventions meta-analysis was not possible and there was either no statistically significant difference between trial arms or findings were not reported. Only three studies reported any adverse events and none of these were serious, however, it is possible that the low incidence was in part due to poor reporting. The quality of the evidence ranged from moderate quality for physical activity interventions and Mediterranean diet to low quality for psychosocial interventions and all other interventions. AUTHORS' CONCLUSIONS: This review provides some evidence that physical activity and psychosocial interventions provide benefit in relation to self-reported fatigue in adults with rheumatoid arthritis. There is currently insufficient evidence of the effectiveness of other non-pharmacological interventions.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1002/14651858.cd008322.pub2

Cites

105 of 105 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,603
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis
Arnett, F. C., Edworthy, S. M., Bloch, D. A., McShane, D. J., Fries, J. F., Cooper, N. S., Healey, L. A., Kaplan, S. R., Liang, M. H., Luthra, H. S., et al. (1988) · Arthritis & Rheumatism · doi:10.1002/art.1780310302 · Cited by 19,753
Pharmacological interventions for somatoform disorders in adults
Kleinstäuber, M., Witthöft, M., Steffanowski, A., van Marwijk, H., Hiller, W., & Lambert, M. J. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010628.pub2 · Cited by 11,369
Revised Criteria for the Classification of Rheumatoid Arthritis
Arnett, F. C. (1990) · Orthopaedic Nursing · doi:10.1097/00006416-199003000-00011 · Cited by 7,742
Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1. The Cochrane Collaboration
Higgins, J., Green, S. R., & Higgins, J. (2008) · Cited by 5,544
Randomized Controlled Trial
Epidoxorubicin In, A., Cascinu, S., Labianca, R., Barone, C., Santoro, O., Carnaghi, C., Frontini, L., Aitini, E., Rota, S., Torri, V., et al. (2009) · Springer eBooks · doi:10.1007/978-0-387-78665-0_6514 · Cited by 1,394
Chapter 12: Interpreting results and drawing conclusions
Schünemann, H. J., Oxman, A. D., Jonathan, J., & Glasziou, P. (2011) · Cited by 873
The prevalence and meaning of fatigue in rheumatic disease.
Wolfe, F., Hawley, D. J., & Wilson, K. (1996) · PubMed · Cited by 639
Fish-Oil Fatty Acid Supplementation in Active Rheumatoid Arthritis
Kremer, J. M., Jubiz, W., Michalek, A., Rynes, R. I., Bartholomew, L. E., Bigaouette, J., Timchalk, M., Beeler, D. A., & Lininger, L. L. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-106-4-497 · Cited by 544

Show all 106 references

Research works printed but not linked: 12

Danoff-Burg, 2006, Benefit finding and expressive writing in adults with lupus or rheumatoid arthritis, Psychology & Health, 21, 651, 10.1080/14768320500456996 · DOI
Hakkinen, 2003, Effects of dynamic strength training on physical function, valpar 9 work sample test, and working capacity in patients with recent-onset rheumatoid arthritis, Arthrits and Rheumatism, 49, 71, 10.1002/art.10902 · DOI
Lumley, 2011, The raised trial: Effects of coping skills training and written emotional disclosure on daily diary outcomes for patients with rheumatoid arthritis, Psychosomatic Medicine, 73, 164
Lumley, 2011, The raised trial: Effects of coping skills training and written emotional disclosure on daily diary outcomes for patients with rheumatoid arthritis, Psychosomatic Medicine, 73, 164
Neuberger, 2007, Predictors of exercise and effects of exercise on symptoms, function, aerobic fitness, and disease outcomes of rheumatoid arthritis, Arthritis and Rheumatism, 57, 943, 10.1002/art.22903 · DOI
Riemsma, 2003, Group education for patients with rheumatoid arthritis and their partners, Arthritis and Rheumatism, 49, 556, 10.1002/art.11207 · DOI
Evers, 2005, Cognitive-behavioral therapy in rheumatoid arthritis [Dutch], Nederlands Tijdschrift Voor Fysiotherapie, 115, 143
Hagfors, 2003, A Mediterranean dietary intervention study of patients with rheumatoid arthritis [PhD Thesis], 184
O'Leary, 1986, Psychological factors in rheumatoid arthritis pain and immune function: a self-efficacy approach [PhD Thesis], 209
Stenstrom, 1993, Dynamic therapeutic exercise in rheumatoid arthritis: Qualitative and quantitative aspects [PhD Thesis], 128
Department of Health, 2006, The Musculoskeletal Services Framework
Hewlett, 2011, Self-management of fatigue in rheumatoid arthritis: a randomised controlled trial of group cognitive behavioural therapy, Annals of the Rheumatic Diseases, 70, 1060, 10.1136/ard.2010.144691 · DOI

Sorted by citations

Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews
Geneen, L. J., Moore, R. A., Clarke, C., Martin, D., Colvin, L. A., & Smith, B. H. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011279.pub3 · Cited by 1,222
Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews
Geneen, L. J., Moore, R. A., Clarke, C., Martin, D., Colvin, L. A., & Smith, B. H. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011279.pub2 · Cited by 719
EULAR recommendations for patient education for people with inflammatory arthritis
Zangi, H. A., Ndosi, M. E., Adams, J., Andersen, L., Bode, C., Boström, C., van Eijk‐Hustings, Y., Gossec, L., Korandová, J., Mendes, G., et al. (2015) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2014-206807 · Cited by 400
2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis
Nikiphorou, E., Santos, E. J. F., Marques, A., Böhm, P., Bijlsma, J. W. J., Daïen, C., Esbensen, B. A., Ferreira, R. J. O., Fragoulis, G. E., Holmes, P., et al. (2021) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2021-220249 · Cited by 318
2021 EULAR recommendations regarding lifestyle behaviours and work participation to prevent progression of rheumatic and musculoskeletal diseases
Gwinnutt, J. M., Wieczorek, M., Balanescu, A. R., Bischoff-Ferrari, H. A., Boonen, A. E. R. C. H., Cavalli, G., de Souza, S., de Thurah, A. L., Dorner, T. E., Moe, R. H., et al. (2022) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2021-222020 · Cited by 269
Perceived Barriers, Facilitators and Benefits for Regular Physical Activity and Exercise in Patients with Rheumatoid Arthritis: A Review of the Literature
Zanten, J. V., Rouse, P. C., Hale, E., Ntoumanis, N., Metsios, G. S., Duda, J. L., & Kitas, G. D. (2015) · Sports Medicine · doi:10.1007/s40279-015-0363-2 · Cited by 262
The Burden of Disease in Rheumatoid Arthritis
Uhlig, T., Moe, R. H., & Kvien, T. K. (2014) · PharmacoEconomics · doi:10.1007/s40273-014-0174-6 · Cited by 209
The effects of the Mediterranean diet on rheumatoid arthritis prevention and treatment: a systematic review of human prospective studies
Forsyth, C., Kouvari, M., D'Cunha, N. M., Georgousopoulou, E. N., Panagiotakos, D. B., Mellor, D. D., Kellett, J., & Naumovski, N. (2017) · Rheumatology International · doi:10.1007/s00296-017-3912-1 · Cited by 196
Effects of exercise and physical activity promotion: meta-analysis informing the 2018 EULAR recommendations for physical activity in people with rheumatoid arthritis, spondyloarthritis and hip/knee osteoarthritis
Osthoff, A.-K. R., Juhl, C. B., Knittle, K. P., Dagfinrud, H. S., Hurkmans, E. J., Braun, J., Schoones, J. W., Vlieland, T. P. M. V., & Niedermann, K. (2018) · RMD Open · doi:10.1136/rmdopen-2018-000713 · Cited by 168
The Effects of Aromatherapy Massage and Reflexology on Pain and Fatigue in Patients with Rheumatoid Arthritis: A Randomized Controlled Trial
Metin, Z. G., & Özdemir, L. (2016) · Pain Management Nursing · doi:10.1016/j.pmn.2016.01.004 · Cited by 154
Exercise-induced hypoalgesia: A meta-analysis of exercise dosing for the treatment of chronic pain
Polaski, A. M., Phelps, A. L., Kostek, M. C., Szucs, K. A., & Kolber, B. J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0210418 · Cited by 156
A Systematic Review of Biological Mechanisms of Fatigue in Chronic Illness
Matura, L. A., Malone, S. K., Jaime-Lara, R. B., & Riegel, B. J. (2018) · Biological Research For Nursing · doi:10.1177/1099800418764326 · Cited by 150
EULAR recommendations for the non-pharmacological management of systemic lupus erythematosus and systemic sclerosis
Parodis, I., Girard-Guyonvarc’h, C., Arnaud, L., Distler, O., Domján, A., van den Ende, C. H. M., Fligelstone, K., Kocher, A., Larosa, M., Lau, M., et al. (2023) · Annals of the Rheumatic Diseases · doi:10.1136/ard-2023-224416 · Cited by 140
Fatigue in inflammatory rheumatic diseases: current knowledge and areas for future research
Davies, K., Dures, E. K., & Ng, W. (2021) · Nature Reviews Rheumatology · doi:10.1038/s41584-021-00692-1 · Cited by 147
Management of fatigue in rheumatoid arthritis
Pope, J. E. (2020) · RMD Open · doi:10.1136/rmdopen-2019-001084 · Cited by 137
Fatigue in Rheumatoid Arthritis
Katz, P. (2017) · Current Rheumatology Reports · doi:10.1007/s11926-017-0649-5 · Cited by 133
The Effect of Exercise on Sleep and Fatigue in Rheumatoid Arthritis: A Randomized Controlled Study
Durcan, L., Wilson, F., & Cunnane, G. (2014) · The Journal of Rheumatology · doi:10.3899/jrheum.131282 · Cited by 121
Anti-Inflammatory Diets and Fatigue
Haß, U., Herpich, C., & Norman, K. (2019) · Nutrients · doi:10.3390/nu11102315 · Cited by 122
Psychological correlates of fatigue in rheumatoid arthritis: A systematic review
Matcham, F., Ali, S., Hotopf, M. H., & Chalder, T. (2015) · Clinical Psychology Review · doi:10.1016/j.cpr.2015.03.004 · Cited by 116
Self-citation
Role of Sleep Disturbance, Depression, Obesity, and Physical Inactivity in Fatigue in Rheumatoid Arthritis
Katz, P., Margaretten, M. E., Trupin, L. S., Schmajuk, G., Yazdany, J., & Yelin, E. H. (2015) · Arthritis Care & Research · doi:10.1002/acr.22577 · Cited by 122
The evidence base for psychological interventions for rheumatoid arthritis: a systematic review of reviews
Prothero, L., Barley, E., Galloway, J., Georgopoulou, S., & Sturt, J. (2018) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2018.03.008 · Cited by 115
Biologic interventions for fatigue in rheumatoid arthritis.
Almeida, C., Choy, E., Hewlett, S., Kirwan, J., Cramp, F., Chalder, T., Pollock, J., & Christensen, R. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008334.pub2 · Cited by 103
Self-citation
Effect of Aerobic Exercise Training on Fatigue in Rheumatoid Arthritis: A Meta‐Analysis
Dartel, S. A. A. R.-V., Repping‐Wuts, H., Flendrie, M., Bleijenberg, G., Metsios, G. S., van den Hout, W. B., van den Ende, C. H. M., Neuberger, G. B., Reid, A., van Riel, P. L. C. M., et al. (2015) · Arthritis Care & Research · doi:10.1002/acr.22561 · Cited by 106
Suppressing Inflammation in Rheumatoid Arthritis: Does Patient Global Assessment Blur the Target? A Practice‐Based Call for a Paradigm Change
Ferreira, R. J. O., Duarte, C. C. M., Ndosi, M. E., de Wit, M. P. T., Gossec, L., & da Silva, J. A. P. (2017) · Arthritis Care & Research · doi:10.1002/acr.23284 · Cited by 104
Yoga in Sedentary Adults with Arthritis: Effects of a Randomized Controlled Pragmatic Trial
Moonaz, S. H., Bingham, C. O., Wissow, L., & Bartlett, S. J. (2015) · The Journal of Rheumatology · doi:10.3899/jrheum.141129 · Cited by 98
Effectiveness of Occupational Therapy Interventions for Adults With Rheumatoid Arthritis: A Systematic Review
Siegel, P., Tencza, M., Apodaca, B., & Poole, J. L. (2016) · American Journal of Occupational Therapy · doi:10.5014/ajot.2017.023176 · Cited by 98
Benefits outweigh the risks: a consensus statement on the risks of physical activity for people living with long-term conditions
Reid, H., Ridout, A. J., Tomaz, S. A., Kelly, P., & Jones, N. (2022) · British Journal of Sports Medicine · doi:10.1136/bjsports-2021-104281 · Cited by 97
Interventions for fatigue in inflammatory bowel disease
Farrell, D., Artom, M., Czuber-Dochan, W., Jelsness-Jørgensen, L. P., Norton, C., & Savage, E. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012005.pub2 · Cited by 89
Nonpharmacological treatment in established rheumatoid arthritis
Küçükdeveci, A. A. (2019) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2019.101482 · Cited by 85
Fatigue in rheumatoid arthritis; a persistent problem: a large longitudinal study
van Steenbergen, H. W., Tsonaka, R., Huizinga, T. W. J., Boonen, A. E. R. C. H., & Mil, A. H. M. V. D. H. (2015) · RMD Open · doi:10.1136/rmdopen-2014-000041 · Cited by 85
Effects of Person-Centered Physical Therapy on Fatigue-Related Variables in Persons With Rheumatoid Arthritis: A Randomized Controlled Trial
Feldthusen, C., Dean, E., Forsblad‐d’Elia, H., & Mannerkorpi, K. (2015) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2015.09.022 · Cited by 82
The Experience of people with rheumatoid arthritis living with fatigue: a qualitative metasynthesis
Primdahl, J., Hegelund, A., Lorenzen, A. G., Loeppenthin, K., Dures, E. K., & Esbensen, B. A. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-024338 · Cited by 80
The Role of Physical Exercise in Chronic Musculoskeletal Pain: Best Medicine—A Narrative Review
la Corte‐Rodríguez, H. D., Román-Belmonte, J. M., Luis, C. R., Madrid-Gonzalez, J., & Rodriguez-Merchan, E. C. (2024) · Healthcare · doi:10.3390/healthcare12020242 · Cited by 93
Do Interventions with Diet or Dietary Supplements Reduce the Disease Activity Score in Rheumatoid Arthritis? A Systematic Review of Randomized Controlled Trials
Nelson, J., Sjöblom, H., Gjertsson, I., Ulven, S. M., Lindqvist, H. M., & Bärebring, L. (2020) · Nutrients · doi:10.3390/nu12102991 · Cited by 81
Effects of diet on the outcomes of rheumatic and musculoskeletal diseases (RMDs): systematic review and meta-analyses informing the 2021 EULAR recommendations for lifestyle improvements in people with RMDs
Gwinnutt, J. M., Wieczorek, M., Rodríguez‐Carrio, J., Balanescu, A. R., Bischoff-Ferrari, H. A., Boonen, A. E. R. C. H., Cavalli, G., de Souza, S., de Thurah, A. L., Dorner, T. E., et al. (2022) · RMD Open · doi:10.1136/rmdopen-2021-002167 · Cited by 86
Fatigue interventions in long term, physical health conditions: A scoping review of systematic reviews
Hulme, K., Safari, R., Thomas, S., Mercer, T. H., White, C. M., van der Linden, M. L., & Moss-Morris, R. E. (2018) · PLoS ONE · doi:10.1371/journal.pone.0203367 · Cited by 79
Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT)
HEWLETT, S. E., Almeida, C., Ambler, N., Blair, P. S., Choy, E., Dures, E. K., Hammond, A., Hollingworth, W., Kadir, B., Kirwan, J., et al. (2019) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2018-214469 · Cited by 75
Self-citation
A biopsychosocial network model of fatigue in rheumatoid arthritis: a systematic review
Geenen, R., & Dures, E. K. (2019) · Lara D. Veeken · doi:10.1093/rheumatology/kez403 · Cited by 73
Predictors of fatigue in rheumatoid arthritis
Druce, K. L., & Basu, N. (2019) · Lara D. Veeken · doi:10.1093/rheumatology/kez346 · Cited by 72
Predictors of Fatigue in Rheumatoid Arthritis Patients in Remission or in a Low Disease Activity State
Olsen, C. L., Lie, E., Kvien, T. K., & Zangi, H. A. (2015) · Arthritis Care & Research · doi:10.1002/acr.22787 · Cited by 69
Celecoxib for rheumatoid arthritis
Fidahić, M., Kadić, A. J., Radić, M., & Puljak, L. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012095.pub2 · Cited by 68
Psychosocial management of chronic pain in patients with rheumatoid arthritis: Challenges and solutions
Sharpe, L. (2016) · Journal of Pain Research · doi:10.2147/jpr.s83653 · Cited by 64
“These results are interesting because, although there has been an increase in recent years in research targeting fatigue as a primary outcome, a Cochrane review 28 found that the evidence for psychosocial interventions effectively targeting fatigue remains low.”
Targets for Health Interventions for Inflammatory Bowel Disease-fatigue
Artom, M., Czuber‐Dochan, W., Sturt, J. A., & Norton, C. S. (2016) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjw029 · Cited by 64
Improvement of Fatigue and Quality of Life in Patients with Quiescent Inflammatory Bowel Disease Following a Personalized Exercise Program
van Erp, L. W., Roosenboom, B., Komdeur, P., Dijkstra-Heida, W., Wisse, J., Horje, C. S. H. T., Liem, C. S., van Cingel, R. E. H., Wahab, P. J., & Groenen, M. J. M. (2020) · Digestive Diseases and Sciences · doi:10.1007/s10620-020-06222-5 · Cited by 62
Determining Pathways to Improvements in Fatigue in Rheumatoid Arthritis: Results From the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
Druce, K. L., Jones, G. T., Macfarlane, G. J., & Basu, N. (2015) · Arthritis & Rheumatology · doi:10.1002/art.39238 · Cited by 61
Effectiveness of self-management interventions in inflammatory arthritis: a systematic review informing the 2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis
Marques, A., Santos, E. J. F., Nikiphorou, E., Bosworth, A., & Carmona, L. (2021) · RMD Open · doi:10.1136/rmdopen-2021-001647 · Cited by 57
Effectiveness of Aquatic Exercises in Women With Rheumatoid Arthritis
Siqueira, U. S., Valente, L. G. O., de Mello, M. T., Szejnfeld, V. L., & Pinheiro, M. M. (2016) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000000564 · Cited by 57
Ideal food pyramid for patients with rheumatoid arthritis: A narrative review
Rondanelli, M., Perdoni, F., Peroni, G., Caporali, R. F., Gasparri, C., Riva, A., Petrangolini, G., Faliva, M. A., Infantino, V., Naso, M., et al. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.08.020 · Cited by 62
Consensus statement on a framework for the management of comorbidity and extra-articular manifestations in rheumatoid arthritis
Loza, E., Lajas, C., Andreu, J. L., Balsa, A., González‐Álvaro, I., Illera, Ó., Jover, J. Á., Mateo, I., Orte, J., Rivera, J., et al. (2014) · Rheumatology International · doi:10.1007/s00296-014-3196-7 · Cited by 52
A mixed-methods systematic review of post-viral fatigue interventions: Are there lessons for long Covid?
Fowler‐Davis, S., Platts, K., Thelwell, M., Woodward, A., & Harrop, D. (2021) · PLoS ONE · doi:10.1371/journal.pone.0259533 · Cited by 51
The Longitudinal Course of Fatigue in Rheumatoid Arthritis: Results from the Norfolk Arthritis Register
Druce, K. L., Jones, G. T., Macfarlane, G. J., Verstappen, S. M. M., & Basu, N. (2015) · The Journal of Rheumatology · doi:10.3899/jrheum.141498 · Cited by 50
Current trends in theranostics for rheumatoid arthritis
Madav, Y., Barve, K. H., & Prabhakar, B. R. (2020) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2020.105240 · Cited by 50
Effectiveness of non-pharmacological and non-surgical interventions for rheumatoid arthritis: an umbrella review
Santos, E. J. F., Duarte, C. C. M., Marques, A., Cardoso, D., Apóstolo, J., da Silva, J. A. P., & Barbieri‐Figueiredo, M. D. C. (2019) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-d-18-00020 · Cited by 48
2018 Chinese guidelines for the diagnosis and treatment of rheumatoid arthritis
Tian, X., Wang, Q., Li, M., Zhao, Y., Zhang, Z., Huang, C., Liu, Y., Xu, H., Chen, Y., Wu, L., et al. (2021) · Rheumatology and Immunology Research · doi:10.2478/rir-2021-0002 · Cited by 49
Non-pharmacological treatment in difficult-to-treat rheumatoid arthritis
Majnik, J., Császár-Nagy, N., Böcskei, G., Bender, T., & Nagy, G. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.991677 · Cited by 47
Practical Guideline for Fatigue Management in Inflammatory Bowel Disease
Kreijne, J. E., Lie, M. R. K. L., Vogelaar, L., & van der Woude, C. J. (2015) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjv168 · Cited by 48
The extra-articular impacts of rheumatoid arthritis: moving towards holistic care
Scott, I. C., Machin, A. R., Mallen, C. D., & Hider, S. (2018) · BMC Rheumatology · doi:10.1186/s41927-018-0039-2 · Cited by 47
Efficacy of non-pharmacological interventions: a systematic review informing the 2023 EULAR recommendations for the management of fatigue in people with inflammatory rheumatic and musculoskeletal diseases
Santos, E. J. F., Farisoğulları, B., Dures, E. K., Geenen, R., & Machado, P. (2023) · RMD Open · doi:10.1136/rmdopen-2023-003350 · Cited by 45
The mediation role of work-life balance stress and chronic fatigue in the relationship between workaholism and depression among Chinese male workers in Hong Kong
Yang, X., Qiu, D., Lau, M. M. C., & Lau, J. T. F. (2020) · Journal of Behavioral Addictions · doi:10.1556/2006.2020.00026 · Cited by 49
Understanding Fatigue in Sjögren’s Syndrome: Outcome Measures, Biomarkers and Possible Interventions
Mæland, E., Miyamoto, S. T., Hammenfors, D., Valim, V., & Jonsson, M. V. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.703079 · Cited by 43
Fatigue in Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Comparison of Mechanisms, Measures and Management
Dey, M., Parodis, I., & Nikiphorou, E. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10163566 · Cited by 47
The role of non-pharmacological interventions in the management of rheumatoid-arthritis-related fatigue
Cramp, F. L. (2019) · Lara D. Veeken · doi:10.1093/rheumatology/kez310 · Cited by 41
Self-citation
Unmet Needs in IBD: the Case of Fatigue
Hindryckx, P., Laukens, D., D’Amico, F., & Danese, S. (2017) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-017-8641-4 · Cited by 41
Moderate-to-high intensity exercise with person-centered guidance influences fatigue in older adults with rheumatoid arthritis
Kucharski, D., Lange, E., Ross, A. B., Svedlund, S., Feldthusen, C., Önnheim, K., Mannerkorpi, K., & Gjertsson, I. (2019) · Rheumatology International · doi:10.1007/s00296-019-04384-8 · Cited by 40
The Effectiveness of Psychological Interventions for Rheumatoid Arthritis (RA): A Systematic Review and Meta-Analysis
Nagy, Z., Szigedi, E., Takács, S., & Császár-Nagy, N. (2023) · Life · doi:10.3390/life13030849 · Cited by 39
Determinants of happiness and quality of life in patients with rheumatoid arthritis: a structural equation modelling approach
Santos, E. J. F., Duarte, C. C. M., Ferreira, R. J. O., Pinto, A. M., Geenen, R., & da Silva, J. A. P. (2018) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2017-212934 · Cited by 39
One in five patients with rapidly and persistently controlled early rheumatoid arthritis report poor well-being after 1 year of treatment
der Elst, K. V., Verschueren, P., Cock, D. D., Groef, A. D., Stouten, V., Pazmiño, S., Vriezekolk, J. E., Joly, J., Moons, P., & Westhovens, R. (2020) · RMD Open · doi:10.1136/rmdopen-2019-001146 · Cited by 39
Remotely delivered cognitive behavioural and personalised exercise interventions for fatigue severity and impact in inflammatory rheumatic diseases (LIFT): a multicentre, randomised, controlled, open-label, parallel-group trial
Bachmair, E., Martin, K. R., Aucott, L. S., Dhaun, N., Dures, E. K., Emsley, R., Gray, S. R., Kidd, E., Кумар, В., Lovell, K., et al. (2022) · The Lancet Rheumatology · doi:10.1016/s2665-9913(22)00156-4 · Cited by 39
Depression, disability and sleep disturbance are the main explanatory factors of fatigue in rheumatoid arthritis: a path analysis model
Silva, C. F. R., Duarte, C. C. M., Ferreira, R. J. O., Santos, E. J. F., & da Silva, J. A. P. (2020) · Clinical and Experimental Rheumatology · doi:10.55563/clinexprheumatol/hkhbad · Cited by 37
Cluster Randomised Trials in Cochrane Reviews: Evaluation of Methodological and Reporting Practice
Richardson, M., Garner, P., & Donegan, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151818 · Cited by 37
‘It's when you're not doing too much you feel tired’: A qualitative exploration of fatigue in end‐stage kidney disease
Picariello, F., Moss-Morris, R. E., Macdougall, I. C., & Chilcot, J. (2017) · British Journal of Health Psychology · doi:10.1111/bjhp.12289 · Cited by 41
Examining the efficacy of social-psychological interventions for the management of fatigue in end-stage kidney disease (ESKD): a systematic review with meta-analysis
Picariello, F., Hudson, J. L., Moss-Morris, R. E., Macdougall, I. C., & Chilcot, J. (2017) · Health Psychology Review · doi:10.1080/17437199.2017.1298045 · Cited by 34
Motivational interviewing: relevance in the treatment of rheumatoid arthritis?
Georgopoulou, S., Prothero, L., Lempp, H. K., Galloway, J. B., & Sturt, J. A. (2015) · Rheumatology · doi:10.1093/rheumatology/kev379 · Cited by 33
Managing fatigue in patients with primary Sjögren’s syndrome: challenges and solutions
Miyamoto, S. T., Lendrem, D. W., Ng, W., Hackett, K. L., & Valim, V. (2019) · Open Access Rheumatology Research and Reviews · doi:10.2147/oarrr.s167990 · Cited by 33
Fatigue independently predicts different work disability dimensions in etanercept-treated rheumatoid arthritis and ankylosing spondylitis patients
Druce, K. L., Aikman, L., Dilleen, M., Burden, A., Szczypa, P., & Basu, N. (2018) · Arthritis Research & Therapy · doi:10.1186/s13075-018-1598-8 · Cited by 36
Celecoxib for rheumatoid arthritis
Fidahić, M., Kadić, A. J., Radić, M., & Puljak, L. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012095 · Cited by 32
Complementary and Alternative Medicine Use in Rheumatoid Arthritis: Considerations for the Pharmacological Management of Elderly Patients
Zhao, S. S., Otieno, F., Akpan, A., & Moots, R. J. (2017) · Drugs & Aging · doi:10.1007/s40266-017-0443-0 · Cited by 30
Future of Rehabilitation Interventions for Rheumatic Patients in the Mediterranean Region
Akıncı, A., & Kılıç, G. (2017) · Mediterranean Journal of Rheumatology · doi:10.31138/mjr.28.2.70 · Cited by 28
A prospective study of fatigue trajectories among in‐centre haemodialysis patients
Picariello, F., Norton, S., Moss-Morris, R. E., Macdougall, I. C., & Chilcot, J. (2019) · British Journal of Health Psychology · doi:10.1111/bjhp.12395 · Cited by 30
Reducing fatigue in pediatric rheumatic conditions: a systematic review
Kant‐Smits, K., van Brussel, M., Nijhof, S. L., & van der Net, J. J. (2021) · Pediatric Rheumatology · doi:10.1186/s12969-021-00580-8 · Cited by 27
Sleep and physical activity: a cross-sectional objective profile of people with rheumatoid arthritis
McKenna, S. G., Tierney, M., O’Neill, A., Fraser, A. D., & Kennedy, N. (2018) · Rheumatology International · doi:10.1007/s00296-018-4009-1 · Cited by 27
Fatigue in patients with rheumatic and musculoskeletal diseases: a scoping review on definitions, measurement instruments, determinants, consequences and interventions
Beckers, E., Hermans, K., van Tubergen, A. M., & Boonen, A. E. R. C. H. (2023) · RMD Open · doi:10.1136/rmdopen-2023-003056 · Cited by 26
Sleep and rheumatic diseases
Boeselt, T., Koczulla, A. R., Nell, C., Beutel, B., Guenter, K., Cassel, W., Hildebrandt, O., Koehler, U., & Kroenig, J. (2019) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2019.101434 · Cited by 25
Predictors of response to TNF inhibitors in rheumatoid arthritis: an individual patient data pooled analysis of randomised controlled trials
Law-Wan, J., Sparfel, M.-A., Derolez, S., Azzopardi, N., Goupille, P., Detert, J., Mulleman, D., & Bejan‐Angoulvant, T. (2021) · RMD Open · doi:10.1136/rmdopen-2021-001882 · Cited by 26
Nonpharmacological interventions for subthreshold depression in adults: A systematic review and network meta-analysis
He, R., Wei, J., Huang, K., Yang, H., Chen, Y., Liu, Z., Ma, L., Jia, Y., & Chen, L. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114897 · Cited by 29
Group cognitive–behavioural programme to reduce the impact of rheumatoid arthritis fatigue: the RAFT RCT with economic and qualitative evaluations
HEWLETT, S. E., Almeida, C., Ambler, N., Blair, P. S., Choy, E., Dures, E. K., Hammond, A., Hollingworth, W., Kadir, B., Kirwan, J., et al. (2019) · Health Technology Assessment · doi:10.3310/hta23570 · Cited by 28
Self-citation
Influence of Blue Mussel (Mytilus edulis) Intake on Disease Activity in Female Patients with Rheumatoid Arthritis: The MIRA Randomized Cross-Over Dietary Intervention
Lindqvist, H. M., Gjertsson, I., Eneljung, T., & Winkvist, A. (2018) · Nutrients · doi:10.3390/nu10040481 · Cited by 26
The feasibility of an exercise intervention to improve sleep (time, quality and disturbance) in people with rheumatoid arthritis: a pilot RCT
McKenna, S. G., Donnelly, A., Esbensen, B. A., Comber, L., Ng, W. L., Anjum, A. M., Fraser, A. D., & Kennedy, N. (2021) · Rheumatology International · doi:10.1007/s00296-020-04760-9 · Cited by 27
Fatigue in rheumatoid arthritis
Choy, E., & Dures, E. K. (2019) · Lara D. Veeken · doi:10.1093/rheumatology/kez314 · Cited by 25
Self-citation
Developing a group intervention to manage fatigue in rheumatoid arthritis through modifying physical activity
Salmon, V. E., HEWLETT, S. E., Walsh, N. E., Kirwan, J., Morris, M., Urban, M., & Cramp, F. L. (2019) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-019-2558-4 · Cited by 26
Self-citation
Fatigue in inflammatory arthritis
Dures, E. K., Cramp, F. L., Hackett, K., & Primdahl, J. (2020) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2020.101526 · Cited by 24
Self-citation
Feel the Fatigue and Be Active Anyway: Physical Activity on High‐Fatigue Days Protects Adults With Arthritis From Decrements in Same‐Day Positive Mood
Hegarty, R. S. M., Conner, T. S., Stebbings, S. M., & Treharne, G. J. (2015) · Arthritis Care & Research · doi:10.1002/acr.22582 · Cited by 24
Economic evaluations of educational, physical, and psychological treatments for fibromyalgia: a systematic review with meta-analysis
Cabral, C. M. N., Miyamoto, G. C., Franco, K. F. M., & Bosmans, J. E. (2021) · Pain · doi:10.1097/j.pain.0000000000002233 · Cited by 24
Validity and reliability of functional assessment of chronic illness treatment-fatigue scale in Turkish patients with type 2 diabetes
Çınar, D., & Yava, A. (2018) · Endocrinología Diabetes y Nutrición · doi:10.1016/j.endinu.2018.01.010 · Cited by 23
Perceived Versus Performance Fatigability in Patients With Rheumatoid Arthritis
Marrelli, K. M., Cheng, A. J., Brophy, J. D., & Power, G. A. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01395 · Cited by 24
Associations between fatigue and physical capacity in people moderately affected by rheumatoid arthritis
Demmelmaier, I., Pettersson, S., Nordgren, B., Dufour, A. B., & Opava, C. H. (2018) · Rheumatology International · doi:10.1007/s00296-018-4140-z · Cited by 22
Correlations of fatigue in Danish patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis
Esbensen, B. A., Stallknecht, S. E., Madsen, M. E., Hagelund, L. M., & Pilgaard, T. (2020) · PLoS ONE · doi:10.1371/journal.pone.0237117 · Cited by 24
Sarilumab: patient-reported outcomes in rheumatoid arthritis
Crotti, C., Biggioggero, M., Becciolini, A., & Favalli, E. G. (2018) · Patient Related Outcome Measures · doi:10.2147/prom.s147286 · Cited by 21
Effects of a Resilience‐Building Energy Management Program on Fatigue and Other Symptoms in Systemic Sclerosis: A Randomized Controlled Trial
Murphy, S. L., Chen, Y. T., Alore, M., Hicks, S., Pape, A., Hassett, A. L., Kratz, A. L., Whibley, D., Harper, A. E., Huang, S., et al. (2023) · Arthritis Care & Research · doi:10.1002/acr.25253 · Cited by 22
Interventions for fatigue in inflammatory bowel disease
Farrell, D., Savage, E., Norton, C. S., Jelsness‐Jørgensen, L., Czuber‐Dochan, W., & Artom, M. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012005 · Cited by 20

Authors: Cramp, F., Hewlett, S., Almeida, C., Kirwan, J. R., Choy, E. H., Chalder, T., Pollock, J., & Christensen, R.
Affiliations: University of the West of England (GB)
Bristol Royal Infirmary (GB)
Cardiff University (GB)
King's College London (GB)
Copenhagen University Hospital (DK)
ORCID: Cramp, Fiona
Hewlett, Sarah
Almeida, Celia
Kirwan, John R
Choy, Ernest HS
Chalder, Trudie
Pollock, Jon
Christensen, Robin
Venue: Cochrane Database of Systematic Reviews
Publisher: Wiley
Published: 2013-08-23
Volume: 2013
Issue: 8
Pages: CD008322-CD008322
ISSN: 1361-6137 (ISSN-L)
1465-1858
DOI: 10.1002/14651858.cd008322.pub2
PMC: PMC11748118
OpenAlex: W1916406953
Cited by: 221
References: 106
Citations by year: 2026: 4 · 2025: 10 · 2024: 19 · 2023: 18 · 2022: 17 · 2021: 22 · 2020: 19 · 2019: 26 · 2018: 24 · 2017: 18 · 2016: 12 · 2015: 24 · 2014: 7
FWCI: 2.33
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Cochrane Database of Systematic Reviews (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Bristol Research (University of Bristol) (submittedVersion)
Explore Bristol Research (submittedVersion)
UWE Research Repository (UWE Bristol) (submittedVersion, cc-by)
Topics: Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords: rheumatoid arthritis, non-pharmacological treatment, physical activity, psychosocial interventions, cognitive behavioral therapy, relaxation training, herbal medicine, omega-3 fatty acids, Mediterranean diet, reflexology, fatigue management, symptom burden, quality of life, anxiety, sleep disorders, risk of bias, harm, cost-effectiveness
MeSH terms: Adult, Arthritis, Rheumatoid, Exercise Therapy, Fatigue, Humans, Middle Aged, Psychotherapy, Reflexotherapy, Fatty Acids, Omega-3, Diet, Mediterranean, Pain Management

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Non-pharmacological interventions for fatigue in rheumatoid arthritis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks