Yoga in Sedentary Adults with Arthritis: Effects of a Randomized Controlled Pragmatic Trial
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Abstract
Objective.: To evaluate the effect of Integral-based hatha yoga in sedentary people with arthritis. Methods.: There were 75 sedentary adults aged 18+ years with rheumatoid arthritis (RA) or knee osteoarthritis randomly assigned to 8 weeks of yoga (two 60-min classes and 1 home practice/wk) or waitlist. Poses were modified for individual needs. The primary endpoint was physical health [Medical Outcomes Study Short Form-36 (SF-36) physical component summary (PCS)] adjusted for baseline; exploratory adjusted outcomes included fitness, mood, stress, self-efficacy, SF-36 health-related quality of life (HRQOL), and RA disease activity. In everyone completing yoga, we explored longterm effects at 9 months. Results.: Participants were mostly female (96%), white (55%), and college-educated (51%), with a mean (SD) age of 52 years (12 yrs). Average disease duration was 9 years and 49% had RA. At 8 weeks, yoga was associated with significantly higher PCS (6.5, 95% CI 2.0–10.7), walking capacity (125 m, 95% CI 15–235), positive affect (5.2, 95% CI 1.4–8.9), and lower Center for Epidemiologic Studies Depression Scale (−3.0, 95% CI −4.8 – −1.3). Significant improvements (p < 0.05) were evident in SF-36 role physical, pain, general health, vitality, and mental health scales. Balance, grip strength, and flexibility were similar between groups. Twenty-two out of 28 in the waitlist group completed yoga. Among all yoga participants, significant (p < 0.05) improvements were observed in mean PCS, flexibility, 6-min walk, and all psychological and most HRQOL domains at 8 weeks with most still evident 9 months later. Of 7 adverse events, none were associated with yoga. Conclusion.: Preliminary evidence suggests yoga may help sedentary individuals with arthritis safely increase physical activity, and improve physical and psychological health and HRQOL. Clinical Trials NCT00349869 .
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There is sufficient evidence to recommend deployment of Tai Chi, yoga, and exercise therapies including coordination/stabilization, strengthening/resistance, and aerobic/cardiorespiratory activities within the VHA.
“The workgroup found there is sufficient evidence to recommend deployment of three types of exercise within the VHA: Tai Chi, 15 -17 yoga, 18 -20 and exercise therapies including coordination/ stabilization, strengthening/resistance, and aerobic/ cardiorespiratory activities. 17 , 21 -25”
From A Research Agenda for Advancing Non-pharmacological Management of Chronic Musculoskeletal Pain: Findings from a VHA State-of-the-art Conference (2018) · cites this paper as [20]
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- Authors
- Moonaz, S. H., Bingham, C. O., Wissow, L., & Bartlett, S. J.
- Affiliations
- Johns Hopkins University (US)
- Venue
- The Journal of Rheumatology
- Publisher
- The Journal of Rheumatology
- Published
- 2015-04-01
- Volume
- 42
- Issue
- 7
- Pages
- 1194-1202
- ISSN
- 0315-162X (ISSN-L)
- 1499-2752
- PMC
- PMC4490021
- OpenAlex
- W2122769618
- Cited by
- 98
- References
- 57
- Citations by year
- 2026: 2 · 2025: 11 · 2024: 9 · 2023: 13 · 2022: 7 · 2021: 10 · 2020: 12 · 2019: 7 · 2018: 11 · 2017: 10 · 2016: 4 · 2015: 2
- FWCI
- 6.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journal of Rheumatology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke (R21NS048593)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (T32AR048522)
- National Center for Complementary and Integrative Health (F31AT003362)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Keywords
- hatha yoga, arthritis, rheumatoid arthritis, knee osteoarthritis, sedentary adults, physical activity, health-related quality of life, physical function, depression, mood, pain, self-efficacy, disease activity, long-term effects
- MeSH terms
- Adult, Aged, Arthritis, Rheumatoid, Female, Humans, Male, Middle Aged, Quality of Life, Yoga, Treatment Outcome, Osteoarthritis, Knee, Sedentary Behavior
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