Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology

The nature of the chemical bond—1992

Pauling, L. C. (1992) · Journal of Chemical Education · doi:10.1021/ed069p519 · Cited by 13,235

Microdetermination of Phosphorus

Chen, P. S., Toribara, T. Y., & Warner, H. R. (1956) · Analytical Chemistry · doi:10.1021/ac60119a033 · Cited by 7,200

Catalysis in chemistry and enzymology

Jencks, W. P. (1969) · Medical Entomology and Zoology · Cited by 3,217

Histochemistry of Hepatic Phosphatases at a Physiologic pH: With Special Reference to the Demonstration of Bile Canaliculi

Wachstein, M., & Meisel, E. (1957) · American Journal of Clinical Pathology · doi:10.1093/ajcp/27.1.13 · Cited by 1,810

Estimation of Plasma Phosphatase by Determination of Hydrolysed Phenol with Amino-antipyrine

Kind, P. R., & King, E. J. (1954) · Journal of Clinical Pathology · doi:10.1136/jcp.7.4.322 · Cited by 1,658

Coupling of enzymes to proteins with glutaraldehyde

Avraméas, S. (1969) · Immunochemistry · doi:10.1016/0019-2791(69)90177-3 · Cited by 1,441

A fine-structure genetic and chemical study of the enzyme alkaline phosphatase of E. Coli I. Purification and characterization of alkaline phosphatase

Garen, A., & Levinthal, C. (1960) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(60)91282-8 · Cited by 1,401

A new micromethod for the colorimetric determination of inorganic phosphate

Itaya, K., & Ui, M. (1966) · Clinica Chimica Acta · doi:10.1016/0009-8981(66)90114-8 · Cited by 829

Microtechnical Demonstration of Phosphatase in Tissue Sections.

Gömöri, G. (1939) · Experimental Biology and Medicine · doi:10.3181/00379727-42-10786 · Cited by 742

The Catalytic and Regulatory Properties of Enzymes

Koshland, D. E., & Neet, K. (1968) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.37.070168.002043 · Cited by 610

Modulation of Phosphate/Pyrophosphate Metabolism to Regenerate the Periodontium: A Novel In Vivo Approach

Rodrigues, T. L., Nagatomo, K. J., Foster, B. L., Nociti, F. H., & Somerman, M. J. (2011) · Journal of Periodontology · doi:10.1902/jop.2011.110103 · Cited by 31

Proteoliposomes as matrix vesicles' biomimetics to study the initiation of skeletal mineralization

Simão, A. M., Yadav, M. C., Ciancaglini, P., & Millán, J. L. (2010) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2010007500008 · Cited by 31

Tissue Nonspecific Alkaline Phosphatase (TNAP) Regulates Cranial Base Growth and Synchondrosis Maturation

Nam, H. K., Sharma, M., Liu, J., & Hatch, N. E. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00161 · Cited by 31

Homoarginine Supplementation Prevents Left Ventricular Dilatation and Preserves Systolic Function in a Model of Coronary Artery Disease

Rodionov, R. N., Begmatov, H., Jarzebska, N., Patel, K., Mills, M. T., Ghani, Z., Khakshour, D., Tamboli, P., Patel, M. N., Abdalla, M., et al. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.012486 · Cited by 31

A ratiometric fluorescent probe for alkaline phosphatase with high sensitivity

Yang, Y. Y., Chen, Z., Pan, R., Shiwei, Z., Shengtao, Y., Yao, T., Weilong, Z., Liyue, W., Weiping, Z., Yufang, X., et al. (2019) · Chinese Chemical Letters · doi:10.1016/j.cclet.2019.04.037 · Cited by 31

Phosphotyrosyl-Protein Phosphatases

Foulkes, J. G. (1983) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-69075-4_5 · Cited by 31

Design, synthesis and biological evaluation of trinary benzocoumarin-thiazoles-azomethines derivatives as effective and selective inhibitors of alkaline phosphatase

Channar, P. A., Irum, H., Mahmood, A., Shabir, G., Zaib, S., Saeed, A., Ashraf, Z., Larik, F. A., Lecka, J., Sévigny, J., et al. (2019) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2019.103137 · Cited by 30

Dental defects in the primary dentition associated with hypophosphatasia from biallelic ALPL mutations

Kramer, K., Chavez, M. B., Tran, A. T., Farah, F., Tan, M. H., Kolli, T. N., dos Santos, E. J. L., Wimer, H. F., Millán, J. L., Suva, L. J., et al. (2020) · Bone · doi:10.1016/j.bone.2020.115732 · Cited by 30

Hypophosphatasia and How Alkaline Phosphatase Promotes Mineralization

Whyte, M. P. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804182-6.00028-9 · Cited by 29

Systemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis

Brichacek, A. L., Benkovic, S. A., Chakraborty, S., Nwafor, D. C., Wang, W., Jun, S., Dakhlallah, D. A., Geldenhuys, W. J., Pinkerton, A. B., Millán, J. L., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-55154-2 · Cited by 29

Efficient one-pot synthesis of 5-perfluoroalkylpyrazoles by cyclization of hydrazone dianions

Ngo, T. N., Ejaz, S. A., Hung, T. Q., Dang, T. T., Iqbal, J., Lecka, J., Sévigny, J., & Langer, P. (2015) · Organic & Biomolecular Chemistry · doi:10.1039/c5ob01151e · Cited by 29

Characterization of a xenogeneic antiserum raised against the fetal germ cells of the mouse: Cross-reactivity with embryonal carcinoma cells

Heath, J. K. (1978) · Cell · doi:10.1016/0092-8674(78)90105-8 · Cited by 29

Calcifying Human Aortic Smooth Muscle Cells Express Different Bone Alkaline Phosphatase Isoforms, Including the Novel B1x Isoform

Haarhaus, M. L., Arnqvist, H. J., & Magnusson, P. (2013) · Journal of Vascular Research · doi:10.1159/000346161 · Cited by 28

Photophysics and phosphate fluorescence sensing by poly(phenylene ethynylene) conjugated polyelectrolytes with branched ammonium side groups

Li, Z., Acharya, R., Wang, S., & Schanze, K. S. (2018) · Journal of Materials Chemistry C · doi:10.1039/c7tc05081j · Cited by 28

Purification and Properties of a Phosphorylase (Phosphoprotein) Phosphatase Associated with an Alkaline Phosphatase of Mr 35000 from Bovine Adrenal Cortex

Li, H. (1979) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1979.tb04251.x · Cited by 28

Intestinal Alkaline Phosphatase Deficiency Leads to Lipopolysaccharide Desensitization and Faster Weight Gain

Yang, Y., Millán, J. L., Mecsas, J. C., & Guillemin, K. J. (2014) · Infection and Immunity · doi:10.1128/iai.02520-14 · Cited by 28

In situ electrochemical analysis of alkaline phosphatase activity in 3D cell cultures

Caviglia, C., Carletto, R. P., Roni, S. D., Hassan, Y. M., Hemanth, S., Dufva, M., & Keller, S. S. (2020) · Electrochimica Acta · doi:10.1016/j.electacta.2020.136951 · Cited by 27

Molecular basis of perinatal hypophosphatasia with tissue‐nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406

Numa‐Kinjoh, N., Ishida, Y., Nasu, M., Sohda, M., Misumi, Y., Noda, T., & Oda, K. (2008) · FEBS Journal · doi:10.1111/j.1742-4658.2008.06414.x · Cited by 27

Hybrid compounds from chalcone and 1,2-benzothiazine pharmacophores as selective inhibitors of alkaline phosphatase isozymes

Ashraf, A., Ejaz, S. A., Rahman, S. U., Siddiqui, W. A., Arshad, M. N., Lecka, J., Sévigny, J., Zayed, M. E. M., Asiri, A. M., Iqbal, J., et al. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.09.063 · Cited by 27

Development of a highly thermostable immunoassay based on a nanobody-alkaline phosphatase fusion protein for carcinoembryonic antigen detection

Lin, J., Yu, J., Wang, H., Xu, Y., Li, F., Chen, X., Liang, Y., Tang, J., Li-li, W., Zhou, Z., et al. (2020) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-020-02456-4 · Cited by 26

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage

Zeiner, J., Loukovaara, S., Losenkova, K., Zuccarini, M., Korhonen, A., Lehti, K., Kauppinen, A., Kaarniranta, K., Müller, C. E., Jalkanen, S., et al. (2019) · Journal of Molecular Medicine · doi:10.1007/s00109-018-01734-0 · Cited by 26

Role of GDP in formyl‐peptide‐receptor‐induced activation of guanine‐nucleotide‐binding proteins in membranes of HL 60 cells

Wieland, T., KREISS, J., Gierschik, P., & Jakobs, K. H. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb16891.x · Cited by 26

Influence of the diversified structural variations at the imine functionality of 4-bromophenylacetic acid derived hydrazones on alkaline phosphatase inhibition: synthesis and molecular modelling studies

Khan, I. A., Ibrar, A., Ejaz, S. A., Khan, S. U., Shah, S. J. A., Hameed, S., Simpson, J., Lecka, J., Sévigny, J., & Iqbal, J. (2015) · RSC Advances · doi:10.1039/c5ra14836g · Cited by 25

Effects of GPI-anchored TNAP on the dynamic structure of model membranes

Garcia, A. F., Simão, A. M., Bolean, M., Hoylaerts, M., Millán, J. L., Ciancaglini, P., & Costa-Filho, A. J. (2015) · Physical Chemistry Chemical Physics · doi:10.1039/c5cp02377g · Cited by 25

A novel highly fluorescent S, N, O co-doped carbon dots for biosensing and bioimaging of copper ions in live cells

Dai, Y., Liu, Z., Bai, Y., Chen, Z., Qin, J., & Feng, F. (2018) · RSC Advances · doi:10.1039/c8ra09298b · Cited by 25

Characterization of a phosphoenzyme intermediate in the reaction of phosphoglycolate phosphatase.

Seal, S. N., & Rose, Z. B. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76454-0 · Cited by 25

Human placental alkaline phosphatase

Chang, T., HUANG, S., Huang, T.-M., & Chang, G. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb17282.x · Cited by 25

Functional assay of the mutant tissue-nonspecific alkaline phosphatase gene using U2OS osteoblast-like cells

Orimo, H., Goseki‐Sone, M., Hosoi, T., & Shimada, T. (2008) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2008.03.015 · Cited by 24

Hypophosphatasia update: recent advances in diagnosis and treatment

Cole, D. (2008) · Clinical Genetics · doi:10.1111/j.1399-0004.2007.00958.x · Cited by 24

Disulfide bonds are critical for tissue-nonspecific alkaline phosphatase function revealed by analysis of mutant proteins bearing a C201-Y or C489-S substitution associated with severe hypophosphatasia

Satou, Y., Al‐Shawafi, H. A., Sultana, S., Makita, S., Sohda, M., & Oda, K. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.01.007 · Cited by 24

The Substrate Specificity of Pantethinase

Duprè, S., Rosei, M. A., Bellussi, L. M., Grosso, E. D., & Cavallini, D. (1973) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1973.tb03173.x · Cited by 24

Distinct Alkaline Phosphatase in Serum of Patients with Lymphatic Leukemia and Infectious Mononucleosis

Neumann, H. G., Moran, E. M., Russell, R. M., & Rosenberg, I. H. (1974) · Science · doi:10.1126/science.186.4159.151 · Cited by 24

Acid phosphatase activity in Pinus pinea – Tuber albidum ectomycorrhizal association

Pasqualini, S., Panara, F., & Antonielli, M. (1992) · Canadian Journal of Botany · doi:10.1139/b92-173 · Cited by 24

The relationship between cholinephosphate phosphatase (alkaline phosphatase) and phosphatidylcholine biosynthesis in HeLa cells

Paddon, H. B., & Vance, D. E. (1977) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(77)90175-8 · Cited by 24

Regulating the Rate of Molecular Self‐Assembly for Targeting Cancer Cells

Zhou, J., Du, X., & Xu, B. (2016) · Angewandte Chemie · doi:10.1002/ange.201600753 · Cited by 23

Pendant-drop method coupled to ultraviolet-visible spectroscopy: A useful tool to investigate interfacial phenomena

Andrade, M. A. R., Favarin, B. Z., Derradi, R., Bolean, M., Simão, A. M., Millán, J. L., Ciancaglini, P., & Ramos, A. P. (2016) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2016.05.085 · Cited by 23

Dry-reagent strips for testing milk pasteurization

Sharma, S., Sehgal, N., & Kumar, A. (2003) · LWT · doi:10.1016/s0023-6438(03)00061-6 · Cited by 23

Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site

Stec, B., Cheltsov, A. V., & Millán, J. L. (2010) · Acta Crystallographica Section F Structural Biology and Crystallization Communications · doi:10.1107/s1744309110019767 · Cited by 23

Effects of terminal mismatches on RNA stability: thermodynamics of duplex formation for ACCGGGp, ACCGGAp, and ACCGGCp

Hickey, D. R., & Turner, D. H. (1985) · Biochemistry · doi:10.1021/bi00336a028 · Cited by 23

Assay Format as a Critical Success Factor for Identification of Novel Inhibitor Chemotypes of Tissue-Nonspecific Alkaline Phosphatase from High-Throughput Screening

Chung, T. D. Y., Sergienko, E. A., & Millán, J. L. (2010) · Molecules · doi:10.3390/molecules15053010 · Cited by 22

Cell‐Compatible Nanoprobes for Imaging Intracellular Phosphatase Activities

Wang, J., Zhou, J., He, H., Wu, D., Du, X., & Xu, B. (2018) · ChemBioChem · doi:10.1002/cbic.201800495 · Cited by 22

Anti-proliferative effect of levamisole on human myeloma cell linesin vitro

Ramanadham, M., & Nageshwari, B. (2010) · Journal of Immunotoxicology · doi:10.3109/1547691x.2010.514871 · Cited by 22

Kinetic aspects of alkaline phosphatase refolding in the presence of α-cyclodextrin

Yazdanparast, R., & Khodagholi, F. (2005) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2005.11.018 · Cited by 22

New Pd(II) schiff base complexes derived from ortho-vanillin and -tyrosine or -glutamic acid: Synthesis, characterization, crystal structures and biological properties

Muche, S., Harms, K., Biernasiuk, A., Malm, A., Popiołek, Ł. P., Hordyjewska, A., Olszewska, A., & Hołyńska, M. (2018) · Polyhedron · doi:10.1016/j.poly.2018.05.056 · Cited by 21

Tetramisole and Levamisole Suppress Neuronal Activity Independently from Their Inhibitory Action on Tissue Non-specific Alkaline Phosphatase in Mouse Cortex

Nowak, L. G., Rosay, B., Czégé, D., & Fonta, C. (2015) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-017-7197-9_12 · Cited by 21

Molecular characterization of tissue-nonspecific alkaline phosphatase with an Ala to Thr substitution at position 116 associated with dominantly inherited hypophosphatasia

Ishida, Y., Komaru, K., & Oda, K. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.12.002 · Cited by 21

Aberrant interchain disulfide bridge of tissue‐nonspecific alkaline phosphatase with an Arg433→Cys substitution associated with severe hypophosphatasia

Nasu, M., Ito, M., Ishida, Y., Numa‐Kinjoh, N., Komaru, K., Nomura, S., & Oda, K. (2006) · FEBS Journal · doi:10.1111/j.1742-4658.2006.05550.x · Cited by 21

Analysis of human bone alkaline phosphatase isoforms: Comparison of isoelectric focusing and ion-exchange high-performance liquid chromatography

Sharp, C. A., Linder, C. H., & Magnusson, P. (2007) · Clinica Chimica Acta · doi:10.1016/j.cca.2006.12.024 · Cited by 21

Allosteric modulation of pyrophosphatase activity of rat osseous plate alkaline phosphatase by magnesium ions

Leone, F. A., de Rezende, L. A., Ciancaglini, P., & Pizauro, J. M. (1998) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(97)00077-0 · Cited by 21

Hydrolysis of Extracellular ATP by Vascular Smooth Muscle Cells Transdifferentiated into Chondrocytes Generates Pi but Not PPi

Buchet, R., Tribes, C., Rouaix, V., Doumèche, B., Fiore, M., Wu, Y., Magne, D., & Mebarek, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22062948 · Cited by 20

An asparagine at position 417 of tissue-nonspecific alkaline phosphatase is essential for its structure and function as revealed by analysis of the N417S mutation associated with severe hypophosphatasia

Sultana, S., Al‐Shawafi, H. A., Makita, S., Sohda, M., Amizuka, N., Takagi, R., & Oda, K. (2013) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2013.04.016 · Cited by 20

Detection of a phosphorylated glycine-serine linker in an IgG-based fusion protein

Tyshchuk, O., Völger, H. R., Ferrara, C., Bulau, P., Koll, H., & Mølhøj, M. (2016) · mAbs · doi:10.1080/19420862.2016.1236165 · Cited by 20

Ontogeny of alkaline phosphatase activity in infant intestines and breast milk

Yang, Y., Rader, E. J., Peters-Carr, M., Bent, R. C., Smilowitz, J. T., Guillemin, K. J., & Rader, B. A. (2019) · BMC Pediatrics · doi:10.1186/s12887-018-1379-1 · Cited by 20

Vitamin B6 cofactors conjugated ovalbumin-stabilized gold nanoclusters: Application in alkaline phosphatase activity detection and generating white-light emission

Upadhyay, Y., Kumar, R., Kumar, S. K. A., & Sahoo, S. K. (2020) · Microchemical Journal · doi:10.1016/j.microc.2020.104859 · Cited by 20

GENETIC AND NON-GENETIC VARIATION OF HUMAN ACID PHOSPHATASES

Sensabaugh, G. F. (1975) · Elsevier eBooks · doi:10.1016/b978-0-12-472701-4.50028-0 · Cited by 20

A sensitive fluorescence biosensor for alkaline phosphatase activity based on the Cu(II)-dependent DNAzyme

Zhao, M., Guo, Y., Wang, L., Luo, F., Lin, C., Lin, Z., & Chen, G. (2016) · Analytica Chimica Acta · doi:10.1016/j.aca.2016.10.033 · Cited by 19

Loss of tissue-nonspecific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

Nwafor, D. C., Chakraborty, S., Brichacek, A. L., Jun, S., Gambill, C. A., Wang, W., Engler-Chiurazzi, E. B., Dakhlallah, D. A., Pinkerton, A. B., Millán, J. L., et al. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.11.016 · Cited by 20

Activity of Hydrolytic Enzymes in Various Regions of Normal Human Brain Tissue

Prabha, M., Ravi, V., & Swamy, N. R. (2012) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-012-0273-0 · Cited by 19

Association of serum alkaline phosphatase with mortality in non-selected European patients with CKD5D: an observational, three-centre survival analysis

Beige, J., Wendt, R. T., Girndt, M., Queck, K.-H., Fiedler, R., & Jehle, P. M. (2014) · BMJ Open · doi:10.1136/bmjopen-2013-004275 · Cited by 19

Organic–inorganic collagen/iota‐carrageenan/hydroxyapatite hybrid membranes are bioactive materials for bone regeneration

Nogueira, L. F. B., Maniglia, B. C., Tapia‐Blácido, D. R., & Ramos, A. P. (2019) · Journal of Applied Polymer Science · doi:10.1002/app.48004 · Cited by 19

Between a rock and a hard place: Regulation of mineralization in the periodontium

Andras, N. L., Mohamed, F. F., Chu, E. Y., & Foster, B. L. (2022) · genesis · doi:10.1002/dvg.23474 · Cited by 18

Delivery of Alkaline Phosphatase Promotes Periodontal Regeneration in Mice

Nagasaki, A., Nagasaki, K., Kear, B. D., Tadesse, W. D., Thumbigere‐Math, V., Millán, J. L., Foster, B. L., & Somerman, M. J. (2021) · Journal of Dental Research · doi:10.1177/00220345211005677 · Cited by 18

Selective inhibition of cancer cells by enzyme-induced gain of function of phosphorylated melittin analogues

Li, Q., Chen, P., Hu, Z., Cao, Y. Y., Chen, L., Chen, Y., Zhao, Y., & Li, Y. (2017) · Chemical Science · doi:10.1039/c7sc03217j · Cited by 18

A simple, sensitive, and label-free assay for alkaline phosphatase activity based on target-promoted exponential strand displacement amplification

Lee, C. Y., Park, K. S., & Park, H. G. (2018) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2018.02.054 · Cited by 18

Circulating and tissue-derived isoforms of bone alkaline phosphatase in Paget's disease of bone

Magnusson, P., Davie, M. W. J., & Sharp, C. A. (2010) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365511003642527 · Cited by 18

1-alpha,25-Dihydroxyvitamin D 3 up-regulates the expression of 2 types of human intestinal alkaline phosphatase alternative splicing variants in Caco-2 cells and may be an important regulator of their expression in gut homeostasis

Noda, S., Yamada, A., Nakaoka, K., & Goseki‐Sone, M. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.07.005 · Cited by 18

The catalytic mechanism of bovine intestinal 5'-nucleotide phosphodiesterase. pH and inhibition studies.

Moe, O. A., & Butler, L. G. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32314-7 · Cited by 18

Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies

Iqbal, J., El–Gamal, M. I., Ejaz, S. A., Lecka, J., Sévigny, J., & Oh, C. (2018) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2018.1428193 · Cited by 17

Dental manifestations of hypophosphatasia: translational and clinical advances

dos Santos, E. J. L., Mohamed, F. F., Kramer, K., & Foster, B. L. (2024) · JBMR Plus · doi:10.1093/jbmrpl/ziae180 · Cited by 16

A novel ratiometric fluorescent sensing method based on MnO2 nanosheet for sensitive detection of alkaline phosphatase in serum

Zuo, Q., Chen, Y., Chen, Z., & Yu, R. (2019) · Talanta · doi:10.1016/j.talanta.2019.120528 · Cited by 16

Applications of fluorescent materials in the detection of alkaline phosphatase activity

Guo, J., Yu, H., & Cui, T. (2020) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.34693 · Cited by 16

Molecular phenotype of tissue-nonspecific alkaline phosphatase with a proline (108) to leucine substitution associated with dominant odontohypophosphatasia

Numa‐Kinjoh, N., Komaru, K., Ishida, Y., Sohda, M., & Oda, K. (2015) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2015.05.006 · Cited by 16

The Combination of Intestinal Alkaline Phosphatase Treatment with Moderate Physical Activity Alleviates the Severity of Experimental Colitis in Obese Mice via Modulation of Gut Microbiota, Attenuation of Proinflammatory Cytokines, Oxidative Stress Biomarkers and DNA Oxidative Damage in Colonic Mucosa

Wójcik-Grzybek, D., Hubalewska‐Mazgaj, M., Surmiak, M., Śliwowski, Z., Dobrut, A., Młodzińska, A., Wojcik, A., Kwiecień, S., Magierowski, M., Mazur-Biały, A. I., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23062964 · Cited by 15

Protective Effect of Alkaline Phosphatase Supplementation on Infant Health

Wu, H., Wang, Y., Li, H., Meng, L., Zheng, N., & Wang, J. (2022) · Foods · doi:10.3390/foods11091212 · Cited by 16

Diversity oriented synthesis of 6-nitro- and 6-aminoquinolones and their activity as alkaline phosphatase inhibitors

Miliutina, M., Ivanov, A., Ejaz, S. A., Iqbal, J., Villinger, A., Iaroshenko, V. O., & Langer, P. (2015) · RSC Advances · doi:10.1039/c5ra10948e · Cited by 16

Hydrolysis and Isomerization of trans,trans‐Farnesyl Diphosphate by Andrographis Tissue‐Culture Enzymes

Mackie, H., & Overton, K. H. (1977) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1977.tb11646.x · Cited by 16

Fructose 1,6-bisphosphatase from rabbit liver. [18O]Phosphate-water exchange as a probe of the catalytic mechanism

Sharp, T. R., & Benkovic, S. J. (1979) · Biochemistry · doi:10.1021/bi00580a036 · Cited by 16

Enzymatically Formed Peptide Assemblies Sequestrate Proteins and Relocate Inhibitors to Selectively Kill Cancer Cells

He, H., Liu, S., Wu, D., & Xu, B. (2020) · Angewandte Chemie · doi:10.1002/ange.202006290 · Cited by 15

Glycosylation‐deficient mutations in tissue‐nonspecific alkaline phosphatase impair its structure and function and are linked to infantile hypophosphatasia

Komaru, K., Satou, Y., Al‐Shawafi, H. A., Numa‐Kinjoh, N., Sohda, M., & Oda, K. (2016) · FEBS Journal · doi:10.1111/febs.13663 · Cited by 15

Tissue nonspecific alkaline phosphatase promotes calvarial progenitor cell cycle progression and cytokinesis via Erk1,2

Nam, H. K., Veselá, I., Siismets, E. M., & Hatch, N. E. (2018) · Bone · doi:10.1016/j.bone.2018.10.013 · Cited by 15

Tissue non-specific alkaline phosphatase activity and mineralization capacity of bi-allelic mutations from severe perinatal and asymptomatic hypophosphatasia phenotypes: Results from an in vitro mutagenesis model

Uday, S., Matsumura, T., Saraff, V., Saito, S., Orimo, H., & Högler, W. (2019) · Bone · doi:10.1016/j.bone.2019.05.031 · Cited by 15

Electrochemical Detection and Capillary Electrophoresis: Comparative Studies for Alkaline Phosphatase (ALP) Release from Living Cells

Balbaied, T., Hogan, A. M., & Moore, E. (2020) · Biosensors · doi:10.3390/bios10080095 · Cited by 15

A dimerization defect caused by a glycine substitution at position 420 by serine in tissue‐nonspecific alkaline phosphatase associated with perinatal hypophosphatasia

Makita, S., Al‐Shawafi, H. A., Sultana, S., Sohda, M., Nomura, S., & Oda, K. (2012) · FEBS Journal · doi:10.1111/febs.12022 · Cited by 15

Vitamin D-restricted high-fat diet down-regulates expression of intestinal alkaline phosphatase isozymes in ovariectomized rats

Nakaoka, K., Yamada, A., Noda, S., & Goseki‐Sone, M. (2018) · Nutrition Research · doi:10.1016/j.nutres.2018.03.001 · Cited by 15

Is alkaline phosphatase biomimeticaly immobilized on titanium able to propagate the biomineralization process?

Andrade, M. A. R., Derradi, R., Simão, A. M., Millán, J. L., Ramos, A. P., Ciancaglini, P., & Bolean, M. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.01.014 · Cited by 15

Polyoxyethylene 9-lauryl ether-solubilized alkaline phosphatase: Synergistic stimulation by zinc and magnesium ions

Ciancaglini, P., Pizauro, J. M., & Leone, F. A. (1992) · International Journal of Biochemistry · doi:10.1016/0020-711x(92)90335-x · Cited by 15

Ultrastructure and histochemistry, of the stomach of Asplanchna sieboldi

Wurdak, E. (1987) · Springer eBooks · doi:10.1007/978-94-009-4059-8_48 · Cited by 15

Purification of RNA 3′‐terminal‐phosphate cyclase from HeLa cells

Vicente, Ó., & Filipowicz, W. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14300.x · Cited by 15

Cell Membrane Enzymes II.

Kramers, M. T. C., Catovsky, D., & Foà, R. (1978) · British Journal of Haematology · doi:10.1111/j.1365-2141.1978.tb03644.x · Cited by 15

Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes

Millán, J. (2006) · Cited by 14

Genetics of Hypophosphatasia

Mornet, É. (2013) · Clinical Reviews in Bone and Mineral Metabolism · doi:10.1007/s12018-013-9140-7 · Cited by 14

Cloning of an alkaline phosphatase gene from the moderately thermophilic bacterium Meiothermus ruber and characterization of the recombinant enzyme

Yurchenko, J. V., Budilov, A. V., Deyev, S. M., Khromov, I. S., & Sobolev, A. Y. (2003) · Molecular Genetics and Genomics · doi:10.1007/s00438-003-0899-y · Cited by 14

Presentation of functional groups on self-assembled supramolecular peptide nanofibers mimicking glycosaminoglycans for directed mesenchymal stem cell differentiation

Yaşa, Ö., Uysal, Ö., Ekiz, M. Ş., Guler, M. O., & Tekinay, A. B. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb00708f · Cited by 14

Synthesis and computational studies of highly selective inhibitors of human recombinant tissue non-specific alkaline phosphatase (h-TNAP): A therapeutic target against vascular calcification

Andleeb, H., Hussain, M., Ejaz, S. A., Sévigny, J., Farman, M., Yasinzai, M., Zhang, J., Iqbal, J., & Hameed, S. (2020) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2020.103999 · Cited by 14

A case of lethal hypophosphatasia providing new insights into the perinatal benign form of hypophosphatasia and expression of the ALPL gene

Heath, I. B., Chabrol, E., Fox, M., Drexler, K., Petit, C., Taillandier, A., de Mazancourt, P., Serre, J., & Mornet, É. (2007) · Clinical Genetics · doi:10.1111/j.1399-0004.2007.00902.x · Cited by 14

In vivo biological activity of retinoids partially correlates to their affinity to recombinant retinoic‐acid receptor α and recombinant‐cellular retinoic‐acid‐binding protein I

Keidel, S., Szardenings, M., & Mueller, W. H. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb17627.x · Cited by 14

Inhibitors of Green Crab (Scylla Serrata) Alkaline Phosphatase

Chen, Q.-X., & Hai‐Meng, Z. H. O. U. (1999) · Journal of enzyme inhibition · doi:10.3109/14756369909030320 · Cited by 14

Thiophosphorylation of Alkaline Phosphatase

Fernley, H. N. (1973) · Nature New Biology · doi:10.1038/newbio241110a0 · Cited by 14

Physiologic Concentrations of Bile Salts Inhibit Rat Hepatic Alkaline Phosphatase but Not the Intestinal Isoenzyme

Martins, M. J., Negrão, M. R., Hipólito-Reis, C., & Azevedo, I. (2000) · Clinical Biochemistry · doi:10.1016/s0009-9120(00)00174-0 · Cited by 14

Fluorogenic assay of alkaline phosphatase activity based on the modulation of excited-state intramolecular proton transfer

Park, J., Helal, A., Kim, H.-S., & Kim, Y. (2012) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2012.07.021 · Cited by 13

Alkaline Phosphatases

Millán, J. L. (2006) · Elsevier eBooks · doi:10.1016/b978-012088562-6/50010-8 · Cited by 4

Biology of Human Alkaline Phosphatases with Special Reference to Cancer

Millán, J. L., Fishman, W. H., & Stinson, R. A. (1995) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408369509084680 · Cited by 118

Oncodevelopmental expression and structure of alkaline phosphatase genes.

Millán, J. L. (1988) · PubMed · Cited by 64

Multisystemic Functions of Alkaline Phosphatases

Buchet, R., Millán, J. L., & Magne, D. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-562-0_3 · Cited by 200

Alkaline phosphatase as a reporter of cancerous transformation

Millán, J. (1992) · Clinica Chimica Acta · doi:10.1016/0009-8981(92)90343-o · Cited by 36