Notes on Subgroup Analyses and Meta‐Regression
Abstract
This chapter contains sections titled: Introduction Computational model Multiple comparisons Software Analyses of subgroups and regression analyses are observational Statistical power for subgroup analyses and meta-regression Summary points
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Several subgroups, such as intervention durations for ALM, included fewer than six RCTs, which may not have adequate power for detecting differences among subgroups.
“Finally, inadequate statistical power for subgroup analyses was noted. Several subgroups (such as intervention durations for ALM) included a small number of RCTs (less than six), which may not have adequate power for detecting differences among subgroups [71,72]; the results of such subgroup analyses should be cautiously interpreted.”
Cites
Improved tests for a random effects meta‐regression with a single covariate
Knapp, G., & Hartung, J. (2003) · Statistics in Medicine · doi:10.1002/sim.1482 · Cited by 2,075 · see citing works
Controlling the risk of spurious findings from meta-regression
Higgins, J. P. T., & Thompson, S. G. (2004) · Statistics in Medicine · doi:10.1002/sim.1752 · Cited by 1,267 · see citing works
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Kasper, L. J., Alderson, R. M., & Hudec, K. L. (2012) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.07.001 · Cited by 414 · see citing works
Liao, C.-D., Chen, H.-C., Huang, S.-W., & Liou, T.-H. (2019) · Nutrients · doi:10.3390/nu11081713 · Cited by 189 · see citing works
Methods for second order meta-analysis and illustrative applications
Schmidt, F. L., & Oh, I.-S. (2013) · Organizational Behavior and Human Decision Processes · doi:10.1016/j.obhdp.2013.03.002 · Cited by 151 · see citing works
Correia, J. C., Waqas, A., Assal, J.-P., Davies, M. J., Somers, F., Golay, A., & Pataky, Z. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2022.996528 · Cited by 104 · see citing works
- Authors
- Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R.
- Affiliations
- Biostat (United States) (US)
- Northwestern University (US)
- Baruch College (US)
- Venue
- Introduction to Meta‐Analysis
- Publisher
- Wiley
- Published
- 2009-03-11
- Pages
- 205-212
- OpenAlex
- W1514150466
- Cited by
- 13
- References
- 2
- Citations by year
- 2025: 1 · 2023: 2 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 1 · 2014: 2 · 2013: 1 · 2012: 1
- Type
- other
- Language
- en
- Open access
- closed
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Keywords
- subgroup analysis, meta-regression, statistical power, multiple comparisons, computational model, observational studies
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