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Immune Response against Protozoan Parasites

Olatunde, Ahmed, Ogunro, Olalekan, Tijjani, Habibu, Obidola, Shakirdeen Mayowa, Akpaki, Mustapha Abdullahi, Yadav, Archana, Nigam, Manisha, Mishra, Abhay Prakash·2023·Parasitic Infections
DOI 10.1002/9781119878063.ch4
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Abstract

Parasitic protozoans such as Trypanosoma and Plasmodium cause many of the most prevalent and dreadful diseases in humans. The survival of these parasitic protozoans relies on the successful evasion of the host organism immune system. These include invasion and replication with host cells, as well as alterations of their surface proteins. In some cases, products from parasitic protozoans are responsible for immunosuppression observed in the host organism and it is associated with antigenic mimicry, which is usually linked to diseases induced by these parasites. Other immune responses to protozoans includes activation of T cells and inflammatory cascade of host organism. The evasion strategies used by parasitic protozoans differ depending on the stage of their life cycle, the route of entry into host organisms and the environment in which they exist. Therefore, this chapter highlights the various immune response mechanisms to parasitic protozoans.

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Metadata

Authors
Olatunde, A., Ogunro, O., Tijjani, H., Obidola, S. M., Akpaki, M. A., Yadav, A., Nigam, M., & Mishra, A. P.
Venue
Parasitic Infections
Publisher
Wiley
Published
2023-07-20
Pages
73-99
DOI
10.1002/9781119878063.ch4
Cited by
5
References
0
Language
en

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CoChat. (2026). Citation check: Immune Response against Protozoan Parasites. https://app.cochat.ai/papers/10.1002/9781119878063.ch4
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Olatunde, A., Ogunro, O., Tijjani, H., Obidola, S. M., Akpaki, M. A., Yadav, A., Nigam, M., & Mishra, A. P. (2023). Immune Response against Protozoan Parasites. Parasitic Infections. https://doi.org/10.1002/9781119878063.ch4